YRC Public Data Repository - Protein Structure Prediction

Protein:	KRE5
Organism:	Saccharomyces cerevisiae
Length:	1365 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for KRE5.

Description	E-value	Query Range	Subject Range
gi\|171795 - gi\|171795\|gb\|AAA34725.1\| KRE5 protein precursor	1417.0	[0..16]	[1365..16]
UGGG1_MOUSE - UDP-glucose:glycoprotein glucosyltransferase 1 OS=Mus musculus GN=Uggt1 PE=1 SV=3	1354.0	[0..3]	[1313..28]
UGGG1_RAT - UDP-glucose:glycoprotein glucosyltransferase 1 OS=Rattus norvegicus GN=Ugcgl1 PE=1 SV=1	1344.0	[0..12]	[1313..13]
gi\|73984134 - gi\|73984134\|ref\|XP_533310.2\| PREDICTED: similar to UDP-glucose ceramide glucosyltransferase-like 1 i...	1340.0	[0..3]	[1313..176]
UGGT1 - UDP-glucose glycoprotein glucosyltransferase 1	1329.0	[0..12]	[1313..37]
gi\|114580782 - gi\|114580782\|ref\|XP_001141314.1\| PREDICTED: UDP-glucose ceramide glucosyltransferase-like 1 isoform ...	1327.0	[0..12]	[1313..37]
gi\|109104565 - gi\|109104565\|ref\|XP_001091250.1\| PREDICTED: UDP-glucose ceramide glucosyltransferase-like 1 isoform ...	1321.0	[0..3]	[1313..4]

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Predicted Domain #1

Region A:
Residues: [1-284]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRLLALVLLL LCAPLRAWTY SLRYGIPESA QVWSILVHLL GDVDNQLLTN LYPLVTGLDD  60
   61 EIDIQENLVA LTSNVLRERY DKEDVADLLE LYASLYPMGM IQHDISSNAE QDDANSSYFV 120
  121 LNGNRYEKPD DVFYLKSKDL TIQQKVPDVD VIQPYDVVIG TNSEAPILIL YGCPTVIDSD 180
  181 FEEFNRNLFM EAMNGEGKFR FIWRSTCSLD GKSVEYPLTH PLEITLQNGS RMSSIPQLKK 240
  241 ILYTVPKEIL VGADNDDQLH DLEPEELREL DLRVTSLISE FYQY

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [285-761]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KKDITATLNF TKSIVNNFPL ISKQLIKVSS VNKDIITSNE ELNSKGFDYN MLGLYINGQN  60
   61 WKITSLTPYN LLTALKTEYQ SLLKITNLLQ ELEPSKCILD SKFLLNKFSQ FSLGKLQNLQ 120
  121 PIKMDLHTIP GFSESVIYFN DIESDPQYDE LVNSVQAFFD KSKFGELPEI KQNWSEIIFV 180
  181 IDFARLEDSE VKEALGGLVR AVNVVSQGYP QRVGLLPFSS DSDKSVVNKI YELKNSTDNL 240
  241 TELKSFLETM LLADGLSANA KHSKHIPVPD VFHLLDELQI DETSIIINGE IYPFRKNAWN 300
  301 YLIAKVIKKD TEFIRKELSN SSPKNKQISV RDLLHYKSAN LRHNKYTPNY FADSVYSSVN 360
  361 NTALESVCSE RIGYYTKNEE YNLLHTITLV DDFGSIHALK RLRNLLHTSF VGVRIRIIHV 420
  421 GDISDIWYQL RGSLSQKDPI GSINTFIDAL KLKKVKSHTY KKSGLNQLGL HKWLPDI

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [762-1027]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PLFELQKGSF IALNGRFIHL DQNEVPETEH FEAIIKREAL RTIDSVFALD LLFPGFSQEI  60
   61 INPDLIEMIS SILTRLFYQG THIYNNGIDY TTESSLPRMD LSEFFRPNNL TMFEDGKSAS 120
  121 IDLLLILDPL EERTQMILSL VEQFRPLKFV NIQVILMPTL ELNIVPIRRI YVDDADIVKS 180
  181 ITSEDSRSDP EVDIEMDVPN SFIVDNNYRI KKLLIELHSF SSKTVLSTGN IDGMGGVCLA 240
  241 LVDSAGNIID KTTTMKTFGY GQFHTD

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #4

Region A:
Residues: [1028-1088]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KFLKGCYIKS CDSRYTVQSF STDGHPDFIP SDSLDILSYN PQKIAVKISE EPTHEEEYEE  60
   61 G

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

		MCM Score	SCOP Match	SCOP Description
View	Download	0.899	d.74.2	C-terminal domain of arginine repressor
View	Download	0.885	d.74.2	C-terminal domain of arginine repressor
View	Download	0.876	d.95.1	Glucose permease domain IIB
View	Download	0.857	d.95.1	Glucose permease domain IIB
View	Download	0.840	d.74.2	C-terminal domain of arginine repressor
View	Download	0.840	d.74.2	C-terminal domain of arginine repressor
View	Download	0.810	d.74.2	C-terminal domain of arginine repressor
View	Download	0.810	d.74.2	C-terminal domain of arginine repressor
View	Download	0.748	d.74.2	C-terminal domain of arginine repressor
View	Download	0.745	d.74.2	C-terminal domain of arginine repressor

Predicted Domain #5

Region A:
Residues: [1089-1365]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RNNDTIINIF TILESGPDEE ERYMQMILSI LSKCPETQKV NFFILDQPFI SDTLRKSCEY  60
   61 INSSDEMRGN VIFLNYEWPQ WLRPQRFSSR RRDVSRFLFL DVLLPQNISK VLYMSPTEVP 120
  121 LDPFDIFQFQ GLKRAPLGLF RMSGDGYWKE GYWEKMLREN NLEFYSTEPA FLVNLERFRE 180
  181 LDAGDKYRIH YQRISTDAMS LVNIGQDLVN NLQLEVPIRF LKGSYKKKLV INDECVSEWK 240
  241 KKINKFASSP GDEDVPGESV SSKYQDSDNA APLHDEL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	44.0
Match:	1g9rA
Description:	Galactosyltransferase LgtC
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits