YRC Public Data Repository - Protein Structure Prediction

Protein:	TIM18
Organism:	Saccharomyces cerevisiae
Length:	192 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TIM18.

Description	E-value	Query Range	Subject Range
TIM18 - Component of the mitochondrial TIM22 complex involved in insertion of polytopic proteins into the in...	2.0E-79	[1..192]	[1..192]
sdh4 - TIM22 inner membrane protein import complex anchor subunit Tim18 DHSD_SCHPO - Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial OS=Schizosaccharomyce...	9.0E-44	[48..181]	[63..186]
DHSD_BOVIN - (Q95123) Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial precursor (C...	4.0E-37	[67..180]	[52..157]
gi\|28194393 - gi\|28194393\|gb\|AAO33541.1\|AF475093_1 liver regeneration-related protein 1 [Rattus norvegicus] gi\|12850891 - gi\|12850891\|dbj\|BAB28885.1\| unnamed protein product [Mus musculus]	6.0E-35	[67..180]	[53..158]
SDHD - succinate dehydrogenase complex, subunit D, integral membrane protein gi\|123999468, gi... - gi\|61361457\|gb\|AAX42051.1\| succinate dehydrogenase complex subunit D integral membrane protein [synt...	2.0E-33	[67..180]	[53..158]
DHSD_ASCSU - Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial OS=Ascaris suum PE=1 ...	4.0E-33	[57..180]	[41..155]
sdhd-1 - status:Confirmed UniProt:O62215 protein_id:CAB04259.1	2.0E-29	[54..178]	[33..142]

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Predicted Domain #1

Region A:
Residues: [1-192]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLLFPGLKPV LNASTVIVNP VRAVFPGLVL STKRSFYSIN RLNAENKIND IANTSKEASS  60
   61 SVQMFKPPEF SQFKDSYQKD YERIAKYTLI PLTMVPFYAS FTGGVINPLL DASLSSIFLI 120
  121 YLQYGFTSCI IDYIPKGKYP RWHKLALYCL YGGSMLSLYG IYELETKNNG FVDLVKKLWN 180
  181 ENDDHLYIFG RN

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits