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View Structure Prediction Details

Protein: GCD1
Organism: Saccharomyces cerevisiae
Length: 578 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GCD1.

Description E-value Query
Range
Subject
Range
GLGL2_ARATH - Glucose-1-phosphate adenylyltransferase large subunit 2, chloroplastic OS=Arabidopsis thaliana GN=AP...
0.0 [24..497] [64..518]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [34..497] [38..481]
gi|13487785 - gi|13487785|gb|AAK27719.1|AF356003_1 ADP-glucose pyrophosphorylase large subunit CagpL2 [Cicer ariet...
0.0 [34..497] [77..521]
gi|5091608 - gi|5091608|gb|AAD39597.1|AC007858_11 10A19I.12 [Oryza sativa (japonica cultivar-group)]
0.0 [9..497] [60..529]
gi|556624 - gi|556624|emb|CAA55516.1| ADP-glucose pyrophosphorylase; glucose-1-phosphate adenylyltransferase [Be...
GLGL1_BETVU - Glucose-1-phosphate adenylyltransferase large subunit, chloroplastic/amyloplastic OS=Beta vulgaris G...
0.0 [34..497] [79..522]
gi|1778436 - gi|1778436|gb|AAB40724.1| ADP-glucose pyrophosphorylase large subunit [Lycopersicon esculentum]
0.0 [30..497] [68..518]
gi|229610847, gi... - gi|229610847|emb|CAX51355.1| large subunit of ADP-glucose pyrophosphorylase [Hordeum vulgare subsp. ...
GLGL1_HORVU - Glucose-1-phosphate adenylyltransferase large subunit 1, chloroplastic/amyloplastic OS=Hordeum vulga...
0.0 [9..497] [63..523]
GLGL2_WHEAT - Glucose-1-phosphate adenylyltransferase large subunit, chloroplastic/amyloplastic OS=Triticum aestiv...
0.0 [9..497] [62..522]

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Predicted Domain #1
Region A:
Residues: [1-345]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSIQAFVFCG KGSNLAPFTQ PDFPFQTQNK DSTAATSGDK LNELVNSALD STVINEFMQH  60
   61 STRLPKALLP IGNRPMIEYV LDWCDQADFK EISVVAPVDE IELIESGLTS FLSLRKQQFE 120
  121 LIYKALSNSN HSHHLQDPKK INFIPSKANS TGESLQKELL PRINGDFVIL PCDFVTDIPP 180
  181 QVLVDQFRNR DDNNLAMTIY YKNSLDSSID KKQQQKQKQQ QFFTVYSENE DSERQPILLD 240
  241 VYSQRDVTKT KYLQIRSHLL WNYPNLTVST KLLNSFIYFC SFELCQLLKL GPQSMSRQAS 300
  301 FKDPFTGNQQ QQNPPTTDDD EDRNHDDDDD YKPSATSIQP TYFKK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 84.154902
Match: 1hv9A_
Description: N-acetylglucosamine 1-phosphate uridyltransferase GlmU, C-terminal domain; N-acetylglucosamine 1-phosphate uridyltransferase GlmU, N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 1.88676710996045 bayes_pls_golite062009
nucleotidyltransferase activity 1.86990263440735 bayes_pls_golite062009
transferase activity 1.47184463413038 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.992215002450258 bayes_pls_golite062009
transferase activity, transferring hexosyl groups 0.796949457473955 bayes_pls_golite062009
acyltransferase activity 0.741838450922005 bayes_pls_golite062009
transferase activity, transferring acyl groups other than amino-acyl groups 0.717805296858439 bayes_pls_golite062009
UDP-glycosyltransferase activity 0.619458068514795 bayes_pls_golite062009
transferase activity, transferring acyl groups 0.555398952276587 bayes_pls_golite062009
binding 0.456682720062287 bayes_pls_golite062009
O-acyltransferase activity 0.319932817519902 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [346-578]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KNDLILDPIN CNKSLSKVFR DLSRRSWQHS KPREPIGIFI LPNETLFIRA NNLNAYMDAN  60
   61 RFVLKIKSQT MFTKNIQIQS AAIGADAIVD PKCQISAHSN VKMSVLGTQA NIGSRCRVAG 120
  121 SLLFPGVHLG DEVILENCII GPMAKIGSKC KLSNCYIEGH YVVEPKNNFK GETLANVYLD 180
  181 EDEEDELIYD DSVIAGESEI AEETDSDDRS DEDSDDSEYT DEYEYEDDGL FER

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 84.154902
Match: 1hv9A_
Description: N-acetylglucosamine 1-phosphate uridyltransferase GlmU, C-terminal domain; N-acetylglucosamine 1-phosphate uridyltransferase GlmU, N-terminal domain
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle