YRC Public Data Repository - Protein Structure Prediction

Protein:	SSP2
Organism:	Saccharomyces cerevisiae
Length:	371 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SSP2.

Description	E-value	Query Range	Subject Range
gi\|16033634 - gi\|16033634\|gb\|AAL13305.1\|AF418016_1 Ssp2p [Saccharomyces cerevisiae]	452.0	[0..1]	[371..1]
gi\|28883273, gi\|... - gi\|28883273\|gb\|AAO49720.1\| TIA-1 [Gallus gallus], gi\|118101449\|ref\|XP_001233232.1\| PREDICTED: simila...	265.0	[0..93]	[356..25]
gi\|54303906 - gi\|54303906\|gb\|AAV33303.1\| aging-associated gene 7 protein [Homo sapiens]	264.0	[0..93]	[356..27]
gi\|73998694 - gi\|73998694\|ref\|XP_865306.1\| PREDICTED: similar to Nucleolysin TIAR (TIA-1 related protein) isoform ...	264.0	[0..93]	[356..27]
gi\|149067624 - gi\|149067624\|gb\|EDM17176.1\| Tial1 cytotoxic granule-associated RNA binding protein-like 1 (mapped), ... gi\|148685700, gi... - gi\|148685700\|gb\|EDL17647.1\| Tial1 cytotoxic granule-associated RNA binding protein-like 1, isoform C...	264.0	[0..93]	[356..27]
gi\|76655193 - gi\|76655193\|ref\|XP_871761.1\| PREDICTED: similar to Nucleolysin TIAR (TIA-1 related protein) isoform ...	264.0	[0..93]	[356..27]

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Predicted Domain #1

Region A:
Residues: [1-154]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MYKNYYSNTE VYKKHKDSGS LRKKALRSRR SSFFSFFNDS SSSNGNEFIG FRRFAKAYLF  60
   61 GREIGSCGTD SYTPVGANVN KRRLKKEDKN DQQLWKRQHH SQGCFFPIDD DSNKQTEAAV 120
  121 NKFYENGEYV NQDLIFKGKV YSEESEVVDE KTAG

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

		MCM Score	SCOP Match	SCOP Description
View	Download	0.322	a.152.1	Antioxidant defence protein AhpD
View	Download	0.316	a.24.16	Nucleotidyltransferase substrate binding subunit/domain
View	Download	0.316	a.24.16	Nucleotidyltransferase substrate binding subunit/domain
View	Download	0.260	d.58.10	Acylphosphatase-like
View	Download	0.213	c.37.1	P-loop containing nucleoside triphosphate hydrolases
View	Download	0.213	c.37.1	P-loop containing nucleoside triphosphate hydrolases
View	Download	0.212	d.58.10	Acylphosphatase-like

Predicted Domain #2

Region A:
Residues: [155-371]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SQNPALLKTR SISLNDIPRG TGISSVLSQV RGGSLERIIV YRYDTPERSL HKVDLFFLNY  60
   61 EGAQSFMRYA KTNIFKVNGV QLKPEWIFLE STYENIMKEQ SVNRIIEEEK FISRCLIVKK 120
  121 SSTTAMPNKS NLNKGQTLEN IDIQELEKDF QNFGEVLEIT PIVSRKLCVS IFFYDISSAM 180
  181 RAMEEYEQKG SYLYNKYFKT WTIWYGKDIT DQPCIDL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	42.522879
Match:	1cvjA
Description:	Poly(A)-binding protein
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits