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View Structure Prediction Details

Protein: LAS17
Organism: Saccharomyces cerevisiae
Length: 633 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for LAS17.

Description E-value Query
Range
Subject
Range
FP1_MYTGA - Adhesive plaque matrix protein OS=Mytilus galloprovincialis GN=FP1 PE=2 SV=1
3.0E-47 [58..628] [101..672]
FP1_MYTCO - Adhesive plaque matrix protein OS=Mytilus coruscus GN=FP1 PE=2 SV=1
9.0E-46 [59..630] [196..777]
TCNA_TRYCR - Sialidase OS=Trypanosoma cruzi GN=TCNA PE=2 SV=1
6.0E-45 [121..630] [595..1111]
SLP1_CLOTM, SLAP... - (Q06852) Cell surface glycoprotein 1 precursor (Outer layer protein B) (S-layer protein 1), Cell sur...
2.0E-42 [77..612] [813..1367]
FP1_MYTED - Adhesive plaque matrix protein (Fragment) OS=Mytilus edulis GN=FP1 PE=1 SV=1
4.0E-42 [58..627] [235..821]
LAS17_YEAST - Proline-rich protein LAS17 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=LAS17 PE=1 SV...
LAS17 - Actin assembly factor, activates the Arp2/3 protein complex that nucleates branched actin filaments;...
8.0E-42 [1..633] [1..633]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
6.0E-41 [87..631] [71..613]
MUC1 - mucin 1, cell surface associated
6.0E-41 [87..631] [71..613]

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Predicted Domain #1
Region A:
Residues: [1-154]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGLLNSSDKE IIKRALPKAS NKIIDVTVAR LYIAYPDKNE WQYTGLSGAL ALVDDLVGNT  60
   61 FFLKLVDING HRGVIWDQEL YVNFEYYQDR TFFHTFEMEE CFAGLLFVDI NEASHFLKRV 120
  121 QKRERYANRK TLLNKNAVAL TKKVREEQKS QVVH

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 49.455932
Match: PF00568
Description: WH1 domain

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [155-426]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GPRGESLIDN QRKRYNYEDV DTIPTTKHKA PPPPPPTAET FDSDQTSSFS DINSTTASAP  60
   61 TTPAPALPPA SPEVRKEETH PKHSLPPLPN QFAPLPDPPQ HNSPPQNNAP SQPQSNPFPF 120
  121 PIPEIPSTQS ATNPFPFPVP QQQFNQAPSM GIPQQNRPLP QLPNRNNRPV PPPPPMRTTT 180
  181 EGSGVRLPAP PPPPRRGPAP PPPPHRHVTS NTLNSAGGNS LLPQATGRRG PAPPPPPRAS 240
  241 RPTPNVTMQQ NPQQYNNSNR PFGYQTNSNM SS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [427-633]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PPPPPVTTFN TLTPQMTAAT GQPAVPLPQN TQAPSQATNV PVAPPPPPAS LGQSQIPQSA  60
   61 PSAPIPPTLP STTSAAPPPP PAFLTQQPQS GGAPAPPPPP QMPATSTSGG GSFAETTGDA 120
  121 GRDALLASIR GAGGIGALRK VDKSQLDKPS VLLQEARGES ASPPAAAGNG GTPGGPPASL 180
  181 ADALAAALNK RKTKVGAHDD MDNGDDW

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 11.97
Match: 1deqA
Description: Fibrinogen
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [525-633]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PPQMPATSTS GGGSFAETTG DAGRDALLAS IRGAGGIGAL RKVDKSQLDK PSVLLQEARG  60
   61 ESASPPAAAG NGGTPGGPPA SLADALAAAL NKRKTKVGAH DDMDNGDDW

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle