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View Structure Prediction Details

Protein: RGA1
Organism: Saccharomyces cerevisiae
Length: 1007 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RGA1.

Description E-value Query
Range
Subject
Range
gi|1835220 - gi|1835220|emb|CAA62445.1| Rga1p (Dbm1p) [Saccharomyces cerevisiae]
886.0 [0..1] [1007..1]
gi|7657353, gi|6... - gi|7657353|ref|NP_056557.1| myosin IXb [Mus musculus], gi|6002741|gb|AAF00118.1|AF143683_1 unconvent...
486.0 [0..196] [1002..1072]
gi|65305717 - gi|65305717|emb|CAI61985.1| myosin 9b [Rattus norvegicus]
473.0 [0..194] [1002..1101]
rga3 - GTPase activating protein Rga3
RGA3_SCHPO - Probable Rho-type GTPase-activating protein 3 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843)...
444.0 [0..11] [1005..17]
gi|1147783, gi|1... - gi|1147783|gb|AAC50402.1| myosin-IXb, pir||A59256 myosin-IXb [similarity] - human
429.0 [0..145] [1002..1085]

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Predicted Domain #1
Region A:
Residues: [1-70]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASTAPNEQF PSCVRCKEFI TTGHAYELGC DRWHTHCFAC YKCEKPLSCE SDFLVLGTGA  60
   61 LICFDCSDSC 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 35.491979
Match: 1b8tA
Description: Cysteine-rich (intestinal) protein, CRP, CRIP
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [71-130]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KNCGKKIDDL AIILSSSNEA YCSDCFKCCK CGENIADLRY AKTKRGLFCL SCHEKLLAKR  60
   61 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 35.491979
Match: 1b8tA
Description: Cysteine-rich (intestinal) protein, CRP, CRIP
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [131-238]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KYYEEKKRRL KKNLPSLPTP VIDNGHTDEV SASAVLPEKT FSRPASLVNE IPSGSEPSKD  60
   61 IETNSSDIVP HFITGYNDSD DNSGSSKFGS NVSIDVIGPE ENSTEHVN

[Run NCBI BLAST on this sequence.]

Detection Method: ab initio
Confidence: 11.62
Match:
Description: No description for 1ldvA was found.

Predicted Domain #4
Region A:
Residues: [239-616]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DDVKEEAEAP SANMSLNVAT DPTLSCKEPP SHSRNLLNKT PLRNSSGQYL AKSPSSYRQG  60
   61 IIVNDSLEES DQIDPPNNSS RNASELLTSV LHSPVSVNMK NPKGSNTDIF NTGEISQMDP 120
  121 SLSRKVLNNI VEETNALQRP VVEVVKEDRS VPDLAGVQQE QAEKYSYSNN SGKGRKISRS 180
  181 LSRRSKDLMI NLKSRATGKQ DSNVKLSPAS KVTSRRSQDL MRDNDSHTGL DTPNSNSTSL 240
  241 DILVNNQKSL NYKRFTDNGT LRVTSGKETA LEEQKNHSFK SPSPIDHLLQ SPATPSNVSM 300
  301 YRTPPLDSSL TFDRRNGSSY SNQNYSIPSW QKTPKTQLEN SDNFEEQKET LYENSESRND 360
  361 PSLDKEIVTA EHYLKQLK

[Run NCBI BLAST on this sequence.]

Detection Method: ab initio
Confidence: 11.89
Match:
Description: No description for 1i3qA was found.

Predicted Domain #5
Region A:
Residues: [617-739]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 INLKELESQR EELMKEITEM KSMKEALRRH IESYNSEKNK LYLDSNELSN NPPMINEISL  60
   61 GESPPVKHVA TASSVARSSV KPKFWKFFSS AKPQTEQSIQ GVSTNNTNSI VKSAPVLLSA 120
  121 PSS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [740-878]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GSNSGRLEIS PPVLQNPNEF SDVRLVPIEN DANMGQSKDG EEYLDGSNLY GSSLVARCNY  60
   61 ENNEIPMILS VCIDFIESDE ENMRSEGIYR KSGSQLVIEE IEKQFSAWKV QQNTETPNIL 120
  121 TEQDLNVVTG VLKRYLRKL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 191.29073
Match: 1am4A
Description: p50 RhoGAP domain
Matching Structure (courtesy of the PDB):

Predicted Domain #7
Region A:
Residues: [879-1007]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PNPIFTFQIY EPLMRLVKSK KMMENLPFVG GKLSLEAKNS DTYMSSKSAL KNILEDLPRE  60
   61 HYRVLRVLSE HIEKVTRYSH WNRMTLYNLA LVFAPGLIRD FSGEKDIIDM KERNYIVAFI 120
  121 FGNYKDILT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 191.29073
Match: 1am4A
Description: p50 RhoGAP domain
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle