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View Structure Prediction Details

Protein: PFY1
Organism: Saccharomyces cerevisiae
Length: 126 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PFY1.

Description E-value Query
Range
Subject
Range
PROF_ANACO - Profilin OS=Ananas comosus PE=1 SV=1
8.0E-51 [1..126] [1..131]
PROF1_RICCO - Profilin-1 OS=Ricinus communis GN=PRO1 PE=2 SV=1
1.0E-50 [1..125] [1..130]
PROF1_WHEAT, PRO... - Profilin-1 (Fragment) OS=Triticum aestivum GN=PRO1 PE=2 SV=1, (P49232) Profilin 1 (Fragment)
1.0E-50 [1..126] [1..131]
PROF_LITCN - Profilin OS=Litchi chinensis PE=1 SV=1
2.0E-50 [1..125] [1..130]
gi|125531458 - gi|125531458|gb|EAY78023.1| hypothetical protein OsI_33063 [Oryza sativa Indica Group]
PROFA_ORYSJ - Profilin-A OS=Oryza sativa subsp. japonica GN=Os10g0323600 PE=2 SV=1
PROFA_ORYSA, PRO... - Profilin-A - Oryza sativa (Rice), (Q9FUD1) Profilin A
5.0E-50 [1..125] [1..130]
PROF3_TOBAC - Profilin-3 OS=Nicotiana tabacum GN=PRO3 PE=2 SV=1
9.0E-50 [1..126] [1..133]
PROF1_HORVU - Profilin-1 OS=Hordeum vulgare GN=PRO1 PE=2 SV=1
gi|1229169 - gi|1229169|gb|AAA92503.1| profilin [Hordeum vulgare]
1.0E-49 [1..126] [1..131]
PROF3_HEVBR - Profilin-3 OS=Hevea brasiliensis PE=1 SV=1
1.0E-49 [1..125] [1..130]
PROF1_SOLLC - Profilin-1 OS=Solanum lycopersicum GN=PRO1 PE=2 SV=1
3.0E-49 [1..126] [1..133]

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Predicted Domain #1
Region A:
Residues: [1-126]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSWQAYTDNL IGTGKVDKAV IYSRAGDAVW ATSGGLSLQP NEIGEIVQGF DNPAGLQSNG  60
   61 LHIQGQKFML LRADDRSIYG RHDAEGVVCV RTKQTVIIAH YPPTVQAGEA TKIVEQLADY 120
  121 LIGVQY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 700.522879
Match: 1yprA_
Description: Profilin (actin-binding protein)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
actin binding 7.981958446142 bayes_pls_golite062009
cytoskeletal protein binding 6.51470611165788 bayes_pls_golite062009
actin monomer binding 3.80837480536839 bayes_pls_golite062009
binding 3.26636517628678 bayes_pls_golite062009
phosphatidylinositol-4,5-bisphosphate binding 3.24248939295046 bayes_pls_golite062009
protein binding 2.14534188091242 bayes_pls_golite062009
phosphoinositide binding 1.69872978885701 bayes_pls_golite062009
phospholipid binding 1.52027694872856 bayes_pls_golite062009
transporter activity 1.434681455285 bayes_pls_golite062009
transmembrane transporter activity 1.23300160340736 bayes_pls_golite062009
active transmembrane transporter activity 0.490905558612378 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle