YRC Public Data Repository - Protein Structure Prediction

Protein:	RPT5
Organism:	Saccharomyces cerevisiae
Length:	434 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RPT5.

Description	E-value	Query Range	Subject Range
Y1297_ARCFU - Cell division cycle protein 48 homolog AF_1297 OS=Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 ... Y1297_ARCFU, YC9... - (O28972) Cell division cycle protein 48 homolog AF1297, Cell division cycle protein 48 homolog AF_12...	0.0	[9..429]	[307..716]
gi\|18159541, gi\|... - gi\|18312110\|ref\|NP_558777.1\| AAA family ATPase, CDC48 subfamily protein [Pyrobaculum aerophilum str....	0.0	[12..433]	[307..707]
gi\|5106179, gi\|1... - gi\|5106179\|dbj\|BAA81490.1\| 699aa long hypothetical transitional endoplasmic reticulum ATPase [Aeropy... gi\|7435761 - pir\|\|B72479 probable transitional endoplasmic reticulum ATPase APE2474 - Aeropyrum pernix (strain K1...	0.0	[9..433]	[275..675]
gi\|7435751 - pir\|\|A69086 cell division control protein Cdc48 - Methanobacterium thermoautotrophicum (strain Delta... gi\|15679634, gi\|... - gi\|2622767\|gb\|AAB86112.1\| cell division control protein Cdc48 [Methanothermobacter thermautotrophicu...	0.0	[12..432]	[333..731]
gi\|18977335, gi\|... - gi\|18977335\|ref\|NP_578692.1\| cell division protein CDC48 [Pyrococcus furiosus DSM 3638], gi\|18893012...	0.0	[12..433]	[337..812]
gi\|3257095, gi\|1... - gi\|3257095\|dbj\|BAA29778.1\| 840aa long hypothetical cell division control protein (transitional endop... gi\|7435754 - pir\|\|H71114 probable cell division control protein (transitional endoplasmic reticulum ATPase) - Pyr...	0.0	[12..433]	[340..815]
YB56_METJA, Y115... - (Q58556) Cell division cycle protein 48 homolog MJ1156, Cell division cycle protein 48 homolog MJ115... Y1156_METJA - Cell division cycle protein 48 homolog MJ1156 OS=Methanocaldococcus jannaschii (strain ATCC 43067 / ...	0.0	[12..405]	[307..674]
gi\|15920392, gi\|... - gi\|15920392\|ref\|NP_376061.1\| hypothetical protein ST0209 [Sulfolobus tokodaii str. 7], gi\|15621174\|d...	0.0	[12..433]	[240..667]
gi\|190407446 - gi\|190407446\|gb\|EDV10713.1\| 26S protease regulatory subunit 6A [Saccharomyces cerevisiae RM11-1a] RPT5 - One of six ATPases of the 19S regulatory particle of the 26S proteasome involved in the degradation ... PRS6A_YEAST - 26S protease regulatory subunit 6A OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RPT5 ... gi\|151945739 - gi\|151945739\|gb\|EDN63980.1\| regulatory particle triple-a protein, or regulatory particle triphosphat...	0.0	[1..434]	[1..434]
gi\|7435762, gi\|5... - pir\|\|D75046 transitional endoplasmic reticulum atpase PAB1478 - Pyrococcus abyssi (strain Orsay), gi... gi\|5458778, gi\|1... - gi\|5458778\|emb\|CAB50265.1\| ATPase of the AAA+ family [Pyrococcus abyssi GE5], gi\|14521559\|ref\|NP_127...	0.0	[12..433]	[340..815]

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Predicted Domain #1

Region A:
Residues: [1-158]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATLEELDAQ TLPGDDELDQ EILNLSTQEL QTRAKLLDNE IRIFRSELQR LSHENNVMLE  60
   61 KIKDNKEKIK NNRQLPYLVA NVVEVMDMNE IEDKENSEST TQGGNVNLDN TAVGKAAVVK 120
  121 TSSRQTVFLP MVGLVDPDKL KPNDLVGVNK DSYLILDT

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [159-351]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LPSEFDSRVK AMEVDEKPTE TYSDVGGLDK QIEELVEAIV LPMKRADKFK DMGIRAPKGA  60
   61 LMYGPPGTGK TLLARACAAQ TNATFLKLAA PQLVQMYIGE GAKLVRDAFA LAKEKAPTII 120
  121 FIDELDAIGT KRFDSEKSGD REVQRTMLEL LNQLDGFSSD DRVKVLAATN RVDVLDPALL 180
  181 RSGRLDRKIE FPL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	559.10721
Match:	1e32A_
Description:	Membrane fusion atpase p97 N-terminal domain , P97-Nn; Membrane fusion atpase p97, D1 domain; Membrane fusion atpase p97 domain 2, P97-Nc
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [352-434]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PSEDSRAQIL QIHSRKMTTD DDINWQELAR STDEFNGAQL KAVTVEAGMI ALRNGQSSVK  60
   61 HEDFVEGISE VQARKSKSVS FYA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	559.10721
Match:	1e32A_
Description:	Membrane fusion atpase p97 N-terminal domain , P97-Nn; Membrane fusion atpase p97, D1 domain; Membrane fusion atpase p97 domain 2, P97-Nc
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits