YRC Public Data Repository - Protein Structure Prediction

Protein:	YOR059C
Organism:	Saccharomyces cerevisiae
Length:	450 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YOR059C.

Description	E-value	Query Range	Subject Range
YOR059C - Hypothetical protein YO059_YEAST - Putative lipase YOR059C OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YOR059C PE=1 SV=...	0.0	[1..450]	[1..450]
gi\|28922217, gi\|... - gi\|32412922\|ref\|XP_326941.1\| predicted protein [Neurospora crassa], gi\|28922217\|gb\|EAA31464.1\| conse... gi\|85098994 - gi\|85098994\|ref\|XP_960700.1\| hypothetical protein NCU06655 [Neurospora crassa OR74A]	2.0E-68	[3..309]	[10..304]
FAM135A - family with sequence similarity 135, member A	1.0E-50	[6..243]	[1249..1464]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	5.0E-50	[2..235]	[77..318]
gi\|222422961, gi... - gi\|30696012\|ref\|NP_851167.1\| unknown protein [Arabidopsis thaliana], gi\|222422961\|dbj\|BAH19465.1\| AT...	2.0E-49	[2..236]	[31..279]

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Predicted Domain #1

Region A:
Residues: [1-256]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTSDKHLFVL IHGLWGNYTH MESMRTILST TLKKEDVNDD MIYFLPKQNA MFKTFDGIEI  60
   61 IGYRTLIEVC EFIRDYKDGK ITKLSVMGYS QGGLVARFMI GKMLTEFKEL FEDIEPQLFI 120
  121 TMATPHLGVE FYNPTGIAYK SALYSALRTL GSTILGKSGR EMFIANSSNN ILVKLSQGEY 180
  181 LEALSLFKWR IAFANVKNDR TVAFYTAFIT DCDPFIDFDN KLKYTFEEKI PGSGYKGILP 240
  241 KIVDLNALNV NSHAPT

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	22.221849
Match:	1eh5A_
Description:	Palmitoyl protein thioesterase 1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
hydrolase activity	0.685577841077355	bayes_pls_golite062009
catalytic activity	0.629869101256762	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [257-450]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KPTKTYKKWG RTILIILVAT FLILPIALVM NGLGTAYSYI VTCKYRKMLS NGILHNEVRG  60
   61 KLGLTEQLKG YVTDAYGSII NSALDMDANY EASNSNLVNE EELPWKEFIQ KYTTINDGVW 120
  121 KSKFKKLPFD ENRKVILRNL NKLKWIRVPI YIKAVNAHGV IVARRGMDEN TAATGIACIE 180
  181 FTAQLLAYLM HKSN

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

		MCM Score	SCOP Match	SCOP Description
View	Download	0.323	a.126.1	Serum albumin-like
View	Download	0.323	a.126.1	Serum albumin-like

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: