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View Structure Prediction Details

Protein: TIR2
Organism: Saccharomyces cerevisiae
Length: 251 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TIR2.

Description E-value Query
Range
Subject
Range
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
3.0E-42 [46..248] [664..856]
gi|840706 - gi|840706|dbj|BAA09333.1| trans-sialidase [Trypanosoma cruzi]
1.0E-40 [3..248] [687..941]
gi|9695347 - gi|9695347|gb|AAF97432.1|U23947_9 VsaC1 [Mycoplasma pulmonis]
1.0E-35 [5..244] [72..317]
OTOGL_MOUSE - Otogelin OS=Mus musculus GN=Otog PE=1 SV=1
5.0E-35 [48..239] [1565..1784]
gi|15828996 - gi|15828996|ref|NP_326356.1| lipoprotein VSAC (fragment) [Mycoplasma pulmonis UAB CTIP]
gi|14089939, gi|... - pir||E90577 lipoprotein vsaC [imported] - Mycoplasma pulmonis (strain UAB CTIP) (fragment), gi|14089...
4.0E-33 [7..242] [315..556]
gi|11545212 - gi|11545212|gb|AAG37800.1|AF198437_1 hypothetical telomeric SfiI fragment 20 protein 3 [Theileria pa...
1.0E-27 [23..230] [21..256]
SPBPJ4664.02 - glycoprotein
YHU2_SCHPO - Uncharacterized threonine-rich GPI-anchored glycoprotein PJ4664.02 OS=Schizosaccharomyces pombe (str...
5.0E-26 [2..240] [1868..2113]

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Predicted Domain #1
Region A:
Residues: [1-119]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAYIKIALLA AIAALASAQT QEEIDELNVI LNDVKSNLQE YISLAEDSSS GFSLSSLPSG  60
   61 VLDIGLALAS ATDDSYTTLY SEVDFAAVSK MLTMVPWYSS RLLPELESLL GTSTTAASS

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 57.958607
Match: PF00660
Description: Seripauperin and TIP1 family

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.834 N/A N/A a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.813 N/A N/A a.13.1 alpha-2-Macroglobulin receptor associated protein (RAP) domain 1
View Download 0.749 N/A N/A f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.725 N/A N/A a.7.7 BAG domain
View Download 0.712 N/A N/A a.45.1 Glutathione S-transferase (GST), C-terminal domain

Predicted Domain #2
Region A:
Residues: [120-251]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TEASSAATSS AVASSSETTS SAVASSSEAT SSAVASSSEA SSSAATSSAV ASSSEATSST  60
   61 VASSTKAASS TKASSSAVSS AVASSTKASA ISQISDGQVQ ATSTVSEQTE NGAAKAVIGM 120
  121 GAGVMAAAAM LL

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.634 0.260 response to stress d.14.1 Ribosomal protein S5 domain 2-like
View Download 0.385 0.000 response to stress d.198.1 Type III secretory system chaperone
View Download 0.583 0.000 response to stress a.85.1 Hemocyanin, N-terminal domain
View Download 0.485 0.000 response to stress a.69.1 C-terminal domain of alpha and beta subunits of F1 ATP synthase
View Download 0.481 N/A N/A d.198.2 Arp2/3 complex subunits
View Download 0.384 N/A N/A d.232.1 Mago nashi protein
View Download 0.358 N/A N/A b.76.2 Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain
View Download 0.341 N/A N/A a.118.9 ENTH/VHS domain
View Download 0.333 N/A N/A b.1.10 Clathrin adaptor appendage domain
View Download 0.299 N/A N/A d.224.1 SufE-like
View Download 0.286 N/A N/A a.1.1 Globin-like
View Download 0.278 N/A N/A a.3.1 Cytochrome c
View Download 0.256 N/A N/A a.78.1 Fatty acid responsive transcription factor FadR, C-terminal domain
View Download 0.239 N/A N/A d.203.1 DsrC, the gamma subunit of dissimilatory sulfite reductase
View Download 0.228 N/A N/A d.74.3 RBP11-like subunits of RNA polymerase
View Download 0.218 N/A N/A d.6.1 Prion-like


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle