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View Structure Prediction Details

Protein: PEX11
Organism: Saccharomyces cerevisiae
Length: 236 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PEX11.

Description E-value Query
Range
Subject
Range
gi|207341480 - gi|207341480|gb|EDZ69527.1| YOL147Cp-like protein [Saccharomyces cerevisiae AWRI1631]
gi|190407206 - gi|190407206|gb|EDV10473.1| peroxisomal membrane protein PMP27 [Saccharomyces cerevisiae RM11-1a]
PEX11 - Peroxisomal membrane protein required for peroxisome proliferation and medium-chain fatty acid oxida...
PEX11_YEAST - Peroxisomal membrane protein PMP27 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PEX11...
gi|151945489 - gi|151945489|gb|EDN63730.1| peroxin [Saccharomyces cerevisiae YJM789]
1.0E-65 [1..236] [1..236]
PX11D_ARATH - Peroxisomal membrane protein 11D OS=Arabidopsis thaliana GN=PEX11D PE=1 SV=2
2.0E-60 [15..232] [15..226]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
3.0E-60 [15..231] [15..225]
gi|8489788 - gi|8489788|gb|AAF75750.1|AF261140_1 unknown [Lycopersicon esculentum]
1.0E-56 [16..232] [15..225]
PX11A_CANBO - Peroxisomal membrane protein PMP30A OS=Candida boidinii GN=PEX11A PE=1 SV=1
9.0E-51 [1..236] [1..254]
PEX11A - peroxisomal biogenesis factor 11 alpha
gi|157928610, gi... - gi|60823999|gb|AAX36664.1| peroxisomal biogenesis factor 11A [synthetic construct], gi|157928610|gb|...
1.0E-50 [13..229] [2..234]
PX11C_MOUSE - Peroxisomal membrane protein 11C OS=Mus musculus GN=Pex11g PE=1 SV=2
1.0E-49 [14..231] [6..228]
PX11A_RAT - Peroxisomal membrane protein 11A OS=Rattus norvegicus GN=Pex11a PE=1 SV=1
3.0E-49 [13..229] [2..233]

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Predicted Domain #1
Region A:
Residues: [1-115]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVCDTLVYHP SVTRFVKFLD GSAGREKVLR LLQYLARFLA VQNSSLLARQ LQAQFTTVRK  60
   61 FLRFLKPLNH LQAAAKFYDN KLASDNVVRV CNVLKNIFFA AYLSLDQVNL LRILK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.620 a.24.3 Cytochromes
View Download 0.728 a.2.7 tRNA-binding arm
View Download 0.661 f.17.1 F1F0 ATP synthase subunit C
View Download 0.651 a.2.7 tRNA-binding arm
View Download 0.608 a.78.1 Fatty acid responsive transcription factor FadR, C-terminal domain
View Download 0.581 f.18.1 F1F0 ATP synthase subunit A
View Download 0.574 a.2.6 Effector domain of the protein kinase pkn/prk1
View Download 0.568 a.7.1 Spectrin repeat
View Download 0.566 d.67.3 Ribosome recycling factor, RRF
View Download 0.550 f.17.2 Cytochrome c oxidase subunit II-like, transmembrane region
View Download 0.538 a.47.2 t-snare proteins
View Download 0.534 a.47.2 t-snare proteins
View Download 0.534 f.32.1 a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)
View Download 0.529 a.7.2 Enzyme IIa from lactose specific PTS, IIa-lac
View Download 0.520 a.78.1 Fatty acid responsive transcription factor FadR, C-terminal domain
View Download 0.498 a.23.1 HSC20 (HSCB), C-terminal oligomerisation domain
View Download 0.489 a.7.1 Spectrin repeat
View Download 0.480 a.2.6 Effector domain of the protein kinase pkn/prk1
View Download 0.462 a.7.1 Spectrin repeat
View Download 0.453 a.24.16 Nucleotidyltransferase substrate binding subunit/domain
View Download 0.448 f.14.1 Voltage-gated potassium channels
View Download 0.446 a.7.1 Spectrin repeat
View Download 0.444 a.47.2 t-snare proteins
View Download 0.441 a.112.1 Description not found.
View Download 0.438 f.14.1 Voltage-gated potassium channels
View Download 0.435 a.24.9 alpha-catenin/vinculin
View Download 0.426 a.24.9 alpha-catenin/vinculin
View Download 0.425 a.7.2 Enzyme IIa from lactose specific PTS, IIa-lac
View Download 0.424 a.2.11 Fe,Mn superoxide dismutase (SOD), N-terminal domain
View Download 0.418 a.24.16 Nucleotidyltransferase substrate binding subunit/domain
View Download 0.409 a.71.1 Endoplasmic reticulum protein ERP29, C-domain
View Download 0.407 d.67.3 Ribosome recycling factor, RRF
View Download 0.397 a.7.1 Spectrin repeat
View Download 0.391 a.7.2 Enzyme IIa from lactose specific PTS, IIa-lac
View Download 0.390 a.2.7 tRNA-binding arm
View Download 0.389 a.7.1 Spectrin repeat
View Download 0.380 a.24.17 Group V grass pollen allergen
View Download 0.374 a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.360 a.7.8 GAT domain
View Download 0.357 a.24.16 Nucleotidyltransferase substrate binding subunit/domain
View Download 0.356 a.77.1 DEATH domain
View Download 0.355 e.37.1 Bifunctional dehydrogenase/ferrochelatase Met8p, dimerisation and C-terminal domains
View Download 0.353 a.100.1 6-phosphogluconate dehydrogenase C-terminal domain-like
View Download 0.352 a.24.16 Nucleotidyltransferase substrate binding subunit/domain
View Download 0.352 a.24.3 Cytochromes
View Download 0.350 a.24.16 Nucleotidyltransferase substrate binding subunit/domain
View Download 0.347 a.2.11 Fe,Mn superoxide dismutase (SOD), N-terminal domain
View Download 0.336 b.88.1 Mss4-like
View Download 0.334 a.29.3 Acyl-CoA dehydrogenase C-terminal domain-like
View Download 0.331 a.24.17 Group V grass pollen allergen
View Download 0.330 a.24.10 Histidine-containing phosphotransfer domain, HPT domain
View Download 0.325 a.90.1 Transcription factor STAT-4 N-domain
View Download 0.325 a.2.6 Effector domain of the protein kinase pkn/prk1
View Download 0.322 a.24.10 Histidine-containing phosphotransfer domain, HPT domain
View Download 0.321 a.24.9 alpha-catenin/vinculin
View Download 0.320 a.73.1 Retrovirus capsid protein, N-terminal core domain
View Download 0.320 a.1.1 Globin-like
View Download 0.317 a.71.1 Endoplasmic reticulum protein ERP29, C-domain
View Download 0.313 a.7.2 Enzyme IIa from lactose specific PTS, IIa-lac
View Download 0.311 a.2.11 Fe,Mn superoxide dismutase (SOD), N-terminal domain
View Download 0.309 f.15.1 Small-conductance potassium channel
View Download 0.308 a.24.17 Group V grass pollen allergen
View Download 0.303 a.61.1 Retroviral matrix proteins
View Download 0.302 a.24.4 Hemerythrin
View Download 0.302 a.75.1 Ribosomal protein S7
View Download 0.301 a.24.14 FAT domain of focal adhesion kinase
View Download 0.300 d.58.44 Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
View Download 0.298 a.151.1 Glutamyl tRNA-reductase dimerization domain
View Download 0.298 a.24.9 alpha-catenin/vinculin
View Download 0.293 a.57.1 Protein HNS-dependent expression A; HdeA
View Download 0.292 a.24.9 alpha-catenin/vinculin
View Download 0.291 a.70.1 N-terminal domain of the delta subunit of the F1F0-ATP synthase
View Download 0.289 f.14.1 Voltage-gated potassium channels
View Download 0.285 f.13.1 Family A G protein-coupled receptor-like
View Download 0.281 a.24.16 Nucleotidyltransferase substrate binding subunit/domain
View Download 0.281 a.7.5 Tubulin chaperone cofactor A
View Download 0.276 a.7.1 Spectrin repeat
View Download 0.274 a.118.11 Cytochrome c oxidase subunit E
View Download 0.271 a.24.3 Cytochromes
View Download 0.267 a.61.1 Retroviral matrix proteins
View Download 0.266 a.70.1 N-terminal domain of the delta subunit of the F1F0-ATP synthase
View Download 0.266 a.118.11 Cytochrome c oxidase subunit E
View Download 0.265 f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.263 a.24.4 Hemerythrin
View Download 0.262 a.74.1 Cyclin-like
View Download 0.261 d.20.1 UBC-like
View Download 0.258 f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.258 f.17.2 Cytochrome c oxidase subunit II-like, transmembrane region
View Download 0.257 a.7.5 Tubulin chaperone cofactor A
View Download 0.252 f.31.1 Photosystem I reaction center subunit XI, PsaL
View Download 0.251 a.71.1 Endoplasmic reticulum protein ERP29, C-domain
View Download 0.251 a.24.10 Histidine-containing phosphotransfer domain, HPT domain
View Download 0.251 a.24.17 Group V grass pollen allergen
View Download 0.249 a.39.2 Insect pheromon/odorant-binding proteins
View Download 0.247 a.24.16 Nucleotidyltransferase substrate binding subunit/domain
View Download 0.247 a.1.1 Globin-like
View Download 0.247 f.14.1 Voltage-gated potassium channels
View Download 0.247 a.7.1 Spectrin repeat
View Download 0.244 f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.244 d.58.44 Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
View Download 0.243 d.67.3 Ribosome recycling factor, RRF
View Download 0.242 f.23.16 Subunit III of photosystem I reaction centre, PsaF
View Download 0.239 a.2.11 Fe,Mn superoxide dismutase (SOD), N-terminal domain
View Download 0.239 a.118.11 Cytochrome c oxidase subunit E
View Download 0.238 d.227.1 OsmC-like
View Download 0.238 a.60.10 Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain
View Download 0.238 a.130.1 Chorismate mutase II
View Download 0.237 e.20.1 Heat shock protein 70kD (HSP70), C-terminal substrate-binding fragment
View Download 0.234 d.67.3 Ribosome recycling factor, RRF
View Download 0.234 a.7.1 Spectrin repeat
View Download 0.232 a.71.1 Endoplasmic reticulum protein ERP29, C-domain
View Download 0.232 a.39.1 EF-hand
View Download 0.231 a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.231 f.17.1 F1F0 ATP synthase subunit C
View Download 0.231 f.17.1 F1F0 ATP synthase subunit C
View Download 0.229 a.22.1 Histone-fold
View Download 0.226 f.31.1 Photosystem I reaction center subunit XI, PsaL
View Download 0.225 a.29.3 Acyl-CoA dehydrogenase C-terminal domain-like
View Download 0.224 a.24.9 alpha-catenin/vinculin
View Download 0.223 a.2.7 tRNA-binding arm
View Download 0.223 f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.222 a.26.1 4-helical cytokines
View Download 0.222 a.2.6 Effector domain of the protein kinase pkn/prk1
View Download 0.220 f.1.4 Bcl-2 inhibitors of programmed cell death
View Download 0.219 a.24.17 Group V grass pollen allergen
View Download 0.218 a.7.1 Spectrin repeat
View Download 0.218 a.35.1 lambda repressor-like DNA-binding domains
View Download 0.217 f.14.1 Voltage-gated potassium channels
View Download 0.217 a.79.1 Antitermination factor NusB
View Download 0.216 a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.216 d.202.1 Transcription factor NusA, N-terminal domain
View Download 0.214 f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.213 a.24.17 Group V grass pollen allergen
View Download 0.213 a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.210 a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.208 a.7.1 Spectrin repeat
View Download 0.208 a.118.11 Cytochrome c oxidase subunit E
View Download 0.208 f.17.1 F1F0 ATP synthase subunit C
View Download 0.208 f.1.4 Bcl-2 inhibitors of programmed cell death
View Download 0.207 i.11.1 Computational models partly based on NMR data
View Download 0.206 c.51.1 Anticodon-binding domain of Class II aaRS
View Download 0.205 a.2.5 Prefoldin
View Download 0.204 a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.203 a.73.1 Retrovirus capsid protein, N-terminal core domain
View Download 0.202 a.26.1 4-helical cytokines

Predicted Domain #2
Region A:
Residues: [116-236]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VIPVTVLTGK KIPRWSNWCW LFGLLSGLAM DLRKIQTSHA QIAAFVKAKS QSQGDEHEDH  60
   61 KKVLGKAYQD RYTALRRLFW DAADSFIVLN NLGYLSSNEE YVALSGVVTS ILGMQDMWKA 120
  121 T

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.547 0.068 peroxisomal membrane a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.887 0.066 peroxisomal membrane a.47.2 t-snare proteins
View Download 0.663 0.041 peroxisomal membrane d.67.3 Ribosome recycling factor, RRF
View Download 0.844 0.021 peroxisomal membrane a.29.5 alpha-ketoacid dehydrogenase kinase, N-terminal domain
View Download 0.521 N/A N/A a.24.3 Cytochromes
View Download 0.518 N/A N/A f.18.1 F1F0 ATP synthase subunit A
View Download 0.514 N/A N/A f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.506 N/A N/A a.24.1 Apolipoprotein
View Download 0.459 N/A N/A i.11.1 Computational models partly based on NMR data
View Download 0.452 N/A N/A a.1.1 Globin-like
View Download 0.424 N/A N/A a.47.2 t-snare proteins
View Download 0.404 N/A N/A a.7.5 Tubulin chaperone cofactor A
View Download 0.404 N/A N/A a.7.2 Enzyme IIa from lactose specific PTS, IIa-lac
View Download 0.402 N/A N/A a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.398 N/A N/A a.2.7 tRNA-binding arm
View Download 0.365 N/A N/A a.29.5 alpha-ketoacid dehydrogenase kinase, N-terminal domain
View Download 0.360 N/A N/A a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.357 N/A N/A a.2.5 Prefoldin
View Download 0.353 N/A N/A f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.343 N/A N/A a.25.1 Ferritin-like
View Download 0.341 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.331 N/A N/A a.24.4 Hemerythrin
View Download 0.331 N/A N/A a.100.1 6-phosphogluconate dehydrogenase C-terminal domain-like
View Download 0.326 N/A N/A f.21.2 Fumarate reductase respiratory complex transmembrane subunits
View Download 0.325 N/A N/A d.110.4 SNARE-like
View Download 0.321 N/A N/A a.7.1 Spectrin repeat
View Download 0.320 N/A N/A a.100.1 6-phosphogluconate dehydrogenase C-terminal domain-like
View Download 0.317 N/A N/A a.7.1 Spectrin repeat
View Download 0.314 N/A N/A a.130.1 Chorismate mutase II
View Download 0.314 N/A N/A f.21.2 Fumarate reductase respiratory complex transmembrane subunits
View Download 0.314 N/A N/A a.47.2 t-snare proteins
View Download 0.300 N/A N/A a.60.10 Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain
View Download 0.298 N/A N/A a.25.1 Ferritin-like
View Download 0.298 N/A N/A a.7.2 Enzyme IIa from lactose specific PTS, IIa-lac
View Download 0.294 N/A N/A a.29.2 Bromodomain
View Download 0.290 N/A N/A a.22.1 Histone-fold
View Download 0.289 N/A N/A d.110.4 SNARE-like
View Download 0.282 N/A N/A f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.282 N/A N/A a.7.2 Enzyme IIa from lactose specific PTS, IIa-lac
View Download 0.280 N/A N/A a.7.7 BAG domain
View Download 0.279 N/A N/A a.7.1 Spectrin repeat
View Download 0.278 N/A N/A a.19.1 Fertilization protein
View Download 0.275 N/A N/A f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.274 N/A N/A a.2.5 Prefoldin
View Download 0.274 N/A N/A a.2.11 Fe,Mn superoxide dismutase (SOD), N-terminal domain
View Download 0.274 N/A N/A f.1.4 Bcl-2 inhibitors of programmed cell death
View Download 0.273 N/A N/A a.7.1 Spectrin repeat
View Download 0.269 N/A N/A d.41.2 Quinolinic acid phosphoribosyltransferase (Nicotinate-nucleotide pyrophosphorylase, NadC), N-terminal domain
View Download 0.268 N/A N/A a.118.13 Arp2/3 complex 16 kDa subunit ARPC5
View Download 0.266 N/A N/A d.96.1 Tetrahydrobiopterin biosynthesis enzymes-like
View Download 0.262 N/A N/A f.18.1 F1F0 ATP synthase subunit A
View Download 0.249 N/A N/A a.7.5 Tubulin chaperone cofactor A
View Download 0.247 N/A N/A a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.244 N/A N/A a.7.4 Smac/diablo
View Download 0.244 N/A N/A a.7.7 BAG domain
View Download 0.243 N/A N/A a.63.1 Apolipophorin-III
View Download 0.243 N/A N/A a.100.1 6-phosphogluconate dehydrogenase C-terminal domain-like
View Download 0.242 N/A N/A a.2.7 tRNA-binding arm
View Download 0.240 N/A N/A a.25.2 Thermoplasma ferritin-like 4-helical bundle
View Download 0.240 N/A N/A f.18.1 F1F0 ATP synthase subunit A
View Download 0.240 N/A N/A a.72.1 Functional domain of the splicing factor Prp18
View Download 0.236 N/A N/A a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.235 N/A N/A a.1.1 Globin-like
View Download 0.235 N/A N/A a.1.1 Globin-like
View Download 0.234 N/A N/A a.48.1 N-terminal domain of cbl (N-cbl)
View Download 0.233 N/A N/A d.185.1 LuxS/MPP-like metallohydrolase
View Download 0.232 N/A N/A a.24.9 alpha-catenin/vinculin
View Download 0.232 N/A N/A a.24.14 FAT domain of focal adhesion kinase
View Download 0.226 N/A N/A a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.226 N/A N/A f.31.1 Photosystem I reaction center subunit XI, PsaL
View Download 0.224 N/A N/A f.18.1 F1F0 ATP synthase subunit A
View Download 0.223 N/A N/A a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.221 N/A N/A a.72.1 Functional domain of the splicing factor Prp18
View Download 0.220 N/A N/A a.47.2 t-snare proteins
View Download 0.219 N/A N/A f.21.2 Fumarate reductase respiratory complex transmembrane subunits
View Download 0.217 N/A N/A a.24.14 FAT domain of focal adhesion kinase
View Download 0.217 N/A N/A a.48.1 N-terminal domain of cbl (N-cbl)
View Download 0.216 N/A N/A f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.214 N/A N/A a.24.17 Group V grass pollen allergen
View Download 0.214 N/A N/A a.19.1 Fertilization protein
View Download 0.211 N/A N/A a.74.1 Cyclin-like
View Download 0.211 N/A N/A f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.209 N/A N/A a.1.1 Globin-like
View Download 0.207 N/A N/A i.11.1 Computational models partly based on NMR data
View Download 0.207 N/A N/A a.7.5 Tubulin chaperone cofactor A
View Download 0.206 N/A N/A d.80.1 Tautomerase/MIF
View Download 0.206 N/A N/A f.31.1 Photosystem I reaction center subunit XI, PsaL
View Download 0.204 N/A N/A a.29.3 Acyl-CoA dehydrogenase C-terminal domain-like
View Download 0.201 N/A N/A a.7.5 Tubulin chaperone cofactor A
View Download 0.201 N/A N/A a.24.3 Cytochromes
View Download 0.201 N/A N/A a.7.1 Spectrin repeat
View Download 0.200 N/A N/A a.60.10 Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle