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View Structure Prediction Details

Protein: WRS1
Organism: Saccharomyces cerevisiae
Length: 432 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for WRS1.

Description E-value Query
Range
Subject
Range
SYWC_RABIT - Tryptophan--tRNA ligase, cytoplasmic OS=Oryctolagus cuniculus GN=WARS PE=2 SV=3
0.0 [3..407] [65..465]
gi|32709 - gi|32709|emb|CAA44450.1| IFP53 [Homo sapiens]
0.0 [3..414] [61..468]
gi|71059845, gi|... - gi|71059845|emb|CAJ18466.1| Wars [Mus musculus], gi|34328206|ref|NP_035840.2| tryptophanyl-tRNA synt...
0.0 [4..407] [66..465]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [3..407] [65..465]
WRS1 - Cytoplasmic tryptophanyl-tRNA synthetase, aminoacylates tryptophanyl-tRNA
SYWC_YEAST - Tryptophan--tRNA ligase, cytoplasmic OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=WRS...
0.0 [1..432] [1..432]
SYW_BOVIN - (P17248) Tryptophanyl-tRNA synthetase (EC 6.1.1.2) (Tryptophan--tRNA ligase) (TrpRS)
0.0 [3..412] [66..470]

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Predicted Domain #1
Region A:
Residues: [1-287]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSNDETVEKV TQQVSELKST DVKEQVVTPW DVEGGVDEQG RAQNIDYDKL IKQFGTKPVN  60
   61 EETLKRFKQV TGREPHHFLR KGLFFSERDF TKILDLYEQG KPFFLYTGRG PSSDSMHLGH 120
  121 MIPFVFTKWL QEVFDVPLVI ELTDDEKFLF KHKLTINDVK NFARENAKDI IAVGFDPKNT 180
  181 FIFSDLQYMG GAFYETVVRV SRQITGSTAK AVFGFNDSDC IGKFHFASIQ IATAFPSSFP 240
  241 NVLGLPDKTP CLIPCAIDQD PYFRVCRDVA DKLKYSKPAL LHSRFFP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 103.09691
Match: 1jiiA_
Description: Tyrosyl-tRNA synthetase (TyrRS)
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [288-432]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ALQGSTTKMS ASDDTTAIFM TDTPKQIQKK INKYAFSGGQ VSADLHRELG GNPDVDVAYQ  60
   61 YLSFFKDDDV FLKECYDKYK SGELLSGEMK KLCIETLQEF VKAFQERRAQ VDEETLDKFM 120
  121 VPHKLVWGEK ERLVAPKPKT KQEKK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 103.09691
Match: 1jiiA_
Description: Tyrosyl-tRNA synthetase (TyrRS)
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle