YRC Public Data Repository - Protein Structure Prediction

Protein:	COQ3
Organism:	Saccharomyces cerevisiae
Length:	316 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for COQ3.

Description	E-value	Query Range	Subject Range
COQ3_RAT - (Q63159) Hexaprenyldihydroxybenzoate methyltransferase, mitochondrial precursor (EC 2.1.1.114) (Dihy...	1.0E-55	[5..314]	[1..273]
COQ3_CANAX - Ubiquinone biosynthesis O-methyltransferase, mitochondrial OS=Candida albicans GN=COQ3 PE=3 SV=1	2.0E-49	[1..315]	[2..326]
gi\|12052971, gi\|... - gi\|32171225\|ref\|NP_059117.2\| methyltransferase COQ3 [Homo sapiens], gi\|12052971\|emb\|CAB66660.1\| hypo...	4.0E-49	[33..314]	[85..332]
UBIE_VIBCH - Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE OS=Vibrio cholerae serotype O1 (strain ... UBIE_VIBCM - Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE OS=Vibrio cholerae serotype O1 (strain ... gi\|229508366, gi... - gi\|229508366\|ref\|ZP_04397870.1\| ubiquinone/menaquinone biosynthesis methyltransferase UbiE/COQ5 [Vib... gi\|229346129, gi... - gi\|229517066\|ref\|ZP_04406512.1\| ubiquinone/menaquinone biosynthesis methyltransferase UbiE/COQ5 [Vib... gi\|229520118, gi... - gi\|229520118\|ref\|ZP_04409546.1\| ubiquinone/menaquinone biosynthesis methyltransferase UbiE/COQ5 [Vib... gi\|229527169, gi... - gi\|229527169\|ref\|ZP_04416563.1\| ubiquinone/menaquinone biosynthesis methyltransferase UbiE/COQ5 [Vib... gi\|229369296, gi... - gi\|229606641\|ref\|YP_002877289.1\| ubiquinone/menaquinone biosynthesis methyltransferase UbiE/COQ5 [Vi... gi\|121587669, gi... - gi\|121587669\|ref\|ZP_01677432.1\| ubiquinone/menaquinone biosynthesis methlytransferase UbiE [Vibrio c... gi\|124115249, gi... - gi\|153214643\|ref\|ZP_01949519.1\| ubiquinone/menaquinone biosynthesis methlytransferase UbiE [Vibrio c... gi\|254851469, gi... - gi\|75829374\|ref\|ZP_00758679.1\| COG2226: Methylase involved in ubiquinone/menaquinone biosynthesis [V... gi\|153222877, gi... - gi\|153222877\|ref\|ZP_01953501.1\| ubiquinone/menaquinone biosynthesis methlytransferase UbiE [Vibrio c... gi\|153801700, gi... - gi\|153801700\|ref\|ZP_01956286.1\| ubiquinone/menaquinone biosynthesis methlytransferase UbiE [Vibrio c... gi\|116216422, gi... - gi\|75823221\|ref\|ZP_00752740.1\| COG2226: Methylase involved in ubiquinone/menaquinone biosynthesis [V... gi\|153818222, gi... - gi\|153818222\|ref\|ZP_01970889.1\| ubiquinone/menaquinone biosynthesis methlytransferase UbiE [Vibrio c... UBIE_VIBC3 - Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE OS=Vibrio cholerae serotype O1 (strain ... gi\|126520347, gi... - gi\|229508952\|ref\|ZP_04398442.1\| ubiquinone/menaquinone biosynthesis methyltransferase UbiE/COQ5 [Vib... gi\|121727801, gi... - gi\|75816414\|ref\|ZP_00746885.1\| COG2226: Methylase involved in ubiquinone/menaquinone biosynthesis [V... gi\|254291829, gi... - gi\|254291829\|ref\|ZP_04962613.1\| ubiquinone/menaquinone biosynthesis methlytransferase UbiE [Vibrio c... gi\|153829106, gi... - gi\|153829106\|ref\|ZP_01981773.1\| ubiquinone/menaquinone biosynthesis methlytransferase UbiE [Vibrio c... UBIE_VIBCH - Ubiquinone/menaquinone biosynthesis methyltransferase ubiE OS=Vibrio cholerae GN=ubiE PE=3 SV=1 gi\|149739586, gi... - gi\|153826648\|ref\|ZP_01979315.1\| ubiquinone/menaquinone biosynthesis methlytransferase UbiE [Vibrio c...	7.0E-49	[69..299]	[14..260]
UBIG_PSEAE - 3-demethylubiquinone-9 3-methyltransferase OS=Pseudomonas aeruginosa GN=ubiG PE=3 SV=1 UBIG_PSEAE - Ubiquinone biosynthesis O-methyltransferase OS=Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C...	6.0E-48	[38..314]	[2..230]
UBIG_RICCN - 3-demethylubiquinone-9 3-methyltransferase OS=Rickettsia conorii GN=ubiG PE=3 SV=1 UBIG_RICCN - Ubiquinone biosynthesis O-methyltransferase OS=Rickettsia conorii (strain ATCC VR-613 / Malish 7) GN...	2.0E-47	[38..314]	[2..282]
gi\|189378929, gi... - gi\|189378929\|gb\|EDU97345.1\| 3-demethylubiquinone-9 3-O-methyltransferase [Escherichia coli O157:H7 s... gi\|13362584, gi\|... - gi\|15832369\|ref\|NP_311142.1\| 3-demethylubiquinone-9 3-methyltransferase [Escherichia coli O157:H7 st... gi\|189372803, gi... - gi\|189372803\|gb\|EDU91219.1\| 3-demethylubiquinone-9 3-O-methyltransferase [Escherichia coli O157:H7 s... gi\|189001920, gi... - gi\|189001920\|gb\|EDU70906.1\| 3-demethylubiquinone-9 3-O-methyltransferase [Escherichia coli O157:H7 s... gi\|187771291, gi... - gi\|187771291\|gb\|EDU35135.1\| 3-demethylubiquinone-9 3-O-methyltransferase [Escherichia coli O157:H7 s... gi\|209765554, gi... - pir\|\|E85862 hypothetical protein ubiG [imported] - Escherichia coli (strain O157:H7, substrain EDL9... gi\|208818924, gi... - gi\|208818924\|ref\|ZP_03259244.1\| 3-demethylubiquinone-9 3-O-methyltransferase [Escherichia coli O157:... gi\|208811904, gi... - gi\|208811904\|ref\|ZP_03253233.1\| 3-demethylubiquinone-9 3-O-methyltransferase [Escherichia coli O157:... gi\|254794123, gi... - gi\|254794123\|ref\|YP_003078960.1\| bifunctional 3-demethylubiquinone-9 3-methyltransferase [Escherichi... gi\|208727784, gi... - gi\|208807983\|ref\|ZP_03250320.1\| 3-demethylubiquinone-9 3-O-methyltransferase [Escherichia coli O157:... gi\|12516567, gi\|... - gi\|15802779\|ref\|NP_288806.1\| 3-demethylubiquinone-9 3-methyltransferase [Escherichia coli O157:H7 ED... gi\|195935605 - gi\|195935605\|ref\|ZP_03080987.1\| 3-demethylubiquinone-9 3-methyltransferase [Escherichia coli O157:H7... UBIG_ECO57 - Ubiquinone biosynthesis O-methyltransferase OS=Escherichia coli O157:H7 GN=ubiG PE=3 SV=1 gi\|189362994, gi... - gi\|189362994\|gb\|EDU81413.1\| 3-demethylubiquinone-9 3-O-methyltransferase [Escherichia coli O157:H7 s... gi\|168761338, gi... - gi\|189368244\|gb\|EDU86660.1\| 3-demethylubiquinone-9 3-O-methyltransferase [Escherichia coli O157:H7 s... gi\|168754977, gi... - gi\|189357734\|gb\|EDU76153.1\| 3-demethylubiquinone-9 3-O-methyltransferase [Escherichia coli O157:H7 s... gi\|168749633, gi... - gi\|188016082\|gb\|EDU54204.1\| 3-demethylubiquinone-9 3-O-methyltransferase [Escherichia coli O157:H7 s... gi\|217327831, gi... - gi\|217327831\|ref\|ZP_03443914.1\| 3-demethylubiquinone-9 3-O-methyltransferase [Escherichia coli O157:... UBIG_ECO5E - Ubiquinone biosynthesis O-methyltransferase OS=Escherichia coli O157:H7 (strain EC4115 / EHEC) GN=ub...	2.0E-47	[29..313]	[1..238]
MENG_STAA1 - Demethylmenaquinone methyltransferase OS=Staphylococcus aureus (strain Mu3 / ATCC 700698) GN=menG PE... MENG_STAAW - Demethylmenaquinone methyltransferase OS=Staphylococcus aureus (strain MW2) GN=menG PE=3 SV=1 MENG_STAAE - Demethylmenaquinone methyltransferase OS=Staphylococcus aureus (strain Newman) GN=menG PE=3 SV=1 MENG_STAA9 - Demethylmenaquinone methyltransferase OS=Staphylococcus aureus (strain JH9) GN=menG PE=3 SV=1 gi\|269203096\|ref... - ubiquinone/menaquinone biosynthesis methyltransferase [Staphylococcus aureus subsp. aureus ED98] gi\|25304996 - pir\|\|G89925 menaquinone biosynthesis methyltransferase [imported] - Staphylococcus aureus (strain N3... MENG_STAAT - Demethylmenaquinone methyltransferase OS=Staphylococcus aureus (strain USA300 / TCH1516) GN=menG PE=... gi\|221140962 - gi\|221140962\|ref\|ZP_03565455.1\| ubiquinone/menaquinone biosynthesis methyltransferase [Staphylococcu... MENG_STAAS - Demethylmenaquinone methyltransferase OS=Staphylococcus aureus (strain MSSA476) GN=menG PE=3 SV=1 gi\|221138325 - gi\|221138325\|ref\|ZP_03563127.1\| ubiquinone/menaquinone biosynthesis methyltransferase [Staphylococcu... MENG_STAAM - Demethylmenaquinone methyltransferase OS=Staphylococcus aureus (strain Mu50 / ATCC 700699) GN=menG P... MENG_STAAN - Demethylmenaquinone methyltransferase OS=Staphylococcus aureus (strain N315) GN=menG PE=1 SV=1 gi\|251802063, gi... - gi\|251814398\|ref\|ZP_04828871.1\| ubiquinone/menaquinone biosynthesis methyltransferase [Staphylococcu... gi\|253315978 - gi\|253315978\|ref\|ZP_04839191.1\| ubiquinone/menaquinone biosynthesis methyltransferase [Staphylococcu... gi\|253732113, gi... - gi\|253732113\|ref\|ZP_04866278.1\| ubiquinone/menaquinone biosynthesis methyltransferase [Staphylococcu... gi\|253728822, gi... - gi\|253733282\|ref\|ZP_04867447.1\| ubiquinone/menaquinone biosynthesis methyltransferase [Staphylococcu... gi\|255006257 - gi\|255006257\|ref\|ZP_05144858.2\| ubiquinone/menaquinone biosynthesis methyltransferase [Staphylococcu... MENG_STAA2 - Demethylmenaquinone methyltransferase OS=Staphylococcus aureus (strain JH1) GN=menG PE=3 SV=1 MENG_STAAC - Demethylmenaquinone methyltransferase OS=Staphylococcus aureus (strain COL) GN=menG PE=3 SV=1	2.0E-47	[85..298]	[8..233]
gi\|148231\|gb\|AAA... - o251 [Escherichia coli] gi\|148231 - gi\|148231\|gb\|AAA67628.1\| o251 [Escherichia coli]	3.0E-47	[70..299]	[6..251]
gi\|205335576, gi... - gi\|205335576\|gb\|EDZ22340.1\| 3-demethylubiquinone-9 3-O-methyltransferase [Salmonella enterica subsp.... gi\|205329247, gi... - gi\|205329247\|gb\|EDZ16011.1\| 3-demethylubiquinone-9 3-O-methyltransferase [Salmonella enterica subsp.... gi\|168466028, gi... - gi\|195631312\|gb\|EDX49872.1\| 3-demethylubiquinone-9 3-O-methyltransferase [Salmonella enterica subsp.... gi\|205349469, gi... - gi\|205349469\|gb\|EDZ36100.1\| 3-demethylubiquinone-9 3-O-methyltransferase [Salmonella enterica subsp.... gi\|205338406, gi... - gi\|205338406\|gb\|EDZ25170.1\| 3-demethylubiquinone-9 3-O-methyltransferase [Salmonella enterica subsp.... gi\|168237290, gi... - gi\|197289661\|gb\|EDY29024.1\| 3-demethylubiquinone-9 3-O-methyltransferase [Salmonella enterica subsp.... UBIG_SALTY - 3-demethylubiquinone-9 3-methyltransferase OS=Salmonella typhimurium GN=ubiG PE=3 SV=2 gi\|204929263, gi... - gi\|204929263\|ref\|ZP_03220406.1\| 3-demethylubiquinone-9 3-O-methyltransferase [Salmonella enterica su... gi\|199604573, gi... - gi\|200387475\|ref\|ZP_03214087.1\| 3-demethylubiquinone-9 3-O-methyltransferase [Salmonella enterica su... UBIG_SALTY - 3-demethylubiquinone-9 3-methyltransferase OS=Salmonella typhimurium GN=ubiG PE=3 SV=2 gi\|194470335, gi... - gi\|194470335\|ref\|ZP_03076319.1\| 3-demethylubiquinone-9 3-O-methyltransferase [Salmonella enterica su... UBIG_SALHS - Ubiquinone biosynthesis O-methyltransferase OS=Salmonella heidelberg (strain SL476) GN=ubiG PE=3 SV=... UBIG_SALNS - Ubiquinone biosynthesis O-methyltransferase OS=Salmonella newport (strain SL254) GN=ubiG PE=3 SV=1 UBIG_SALTY - Ubiquinone biosynthesis O-methyltransferase OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC ... gi\|168817994, gi... - gi\|205345145\|gb\|EDZ31909.1\| 3-demethylubiquinone-9 3-O-methyltransferase [Salmonella enterica subsp.... UBIG_SALDC - Ubiquinone biosynthesis O-methyltransferase OS=Salmonella dublin (strain CT_02021853) GN=ubiG PE=3 S... gi\|197263792, gi... - gi\|197263792\|ref\|ZP_03163866.1\| 3-demethylubiquinone-9 3-O-methyltransferase [Salmonella enterica su... UBIG_SALA4 - Ubiquinone biosynthesis O-methyltransferase OS=Salmonella agona (strain SL483) GN=ubiG PE=3 SV=1 UBIG_SALSV - Ubiquinone biosynthesis O-methyltransferase OS=Salmonella schwarzengrund (strain CVM19633) GN=ubiG P... lcl\|NC_016856.1_... - [gene=ubiG] [protein=3-demethylubiquinone-9 3-methyltransferase] [protein_id=YP_005238346.1] [locati...	4.0E-47	[29..313]	[1..238]

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Predicted Domain #1

Region A:
Residues: [1-68]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGFIMLLRSR FLKVIHVRKQ LSACSRFAIQ TQTRCKSTDA SEDEVKHFQE LAPTWWDTDG  60
   61 SQRILHKM

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	5.39794
Match:	1fp1D_
Description:	Chalcone O-methyltransferase
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [69-316]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NLTRLDFVQR TVRNQVKIQN PEIFVPGFNY KEFLPEYVCD NIQREMQESI ETNLDKRPEV  60
   61 SVLDVGCGGG ILSESLARLK WVKNVQGIDL TRDCIMVAKE HAKKDPMLEG KINYECKALE 120
  121 DVTGQFDIIT CMEMLEHVDM PSEILRHCWS RLNPEKGILF LSTINRDLIS WFTTIFMGEN 180
  181 VLKIVPKGTH HLSKYINSKE ILAWFNDNYS GQFRLLDLKG TMYLPYQGWV EHDCSDVGNY 240
  241 FMAIQRLN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	35.0
Match:	1kp9A_
Description:	CmaA1
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits