YRC Public Data Repository - Protein Structure Prediction

Protein:	GAS5
Organism:	Saccharomyces cerevisiae
Length:	484 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GAS5.

Description	E-value	Query Range	Subject Range
gi\|18073451, gi\|... - gi\|49529260\|emb\|CAG62926.1\| unnamed protein product [Candida glabrata], gi\|18073451\|emb\|CAC83345.1\| ... gi\|50295070, gi\|... - gi\|50295070\|ref\|XP_449946.1\| hypothetical protein CAGL0M13849g [Candida glabrata CBS138], gi\|4952926...	0.0	[8..466]	[6..469]
PHR1_CANAL - pH-responsive protein 1 OS=Candida albicans GN=PHR1 PE=2 SV=2	0.0	[2..466]	[4..480]
gi\|10441337 - gi\|10441337\|gb\|AAG16996.1\|AF184908_1 pH-regulated protein 2 [Candida dubliniensis] gi\|241947959, gi... - gi\|241947959\|ref\|XP_002416702.1\| pH-regulated protein 2 [Candida dubliniensis CD36], gi\|223640040\|em...	0.0	[1..465]	[1..467]
EPD1_CANMA - Protein EPD1 OS=Candida maltosa GN=EPD1 PE=3 SV=1	0.0	[1..465]	[1..467]
gi\|3730 - gi\|3730\|emb\|CAA37512.1\| glycolipid-anchored surface protein [Saccharomyces cerevisiae] gi\|190408533 - gi\|190408533\|gb\|EDV11798.1\| cell surface glycoprotein 115-120 kDa [Saccharomyces cerevisiae RM11-1a] gi\|151946016 - gi\|151946016\|gb\|EDN64248.1\| glycophospholipid-anchored surface protein [Saccharomyces cerevisiae YJM...	0.0	[1..466]	[1..469]

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Predicted Domain #1

Region A:
Residues: [1-59]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLLRSLTSAF VLSAGLAQAA SSSNSSTPSI EIKGNAFFNS ESGERFYIRG VDYQPGGSS

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [71-86]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 CDRDVPVLKD LGINTV

[Run NCBI BLAST on this sequence.]

Region C:
Residues: [208-328]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LAAEYFNCGD EADARIDMFG VNDYSWCGES SFVVSGYSTK MKLYQDYSVP VFLSEFGCNQ  60
   61 VKSSRPFTEI EAIYSTQMSS VFSGGLVYEY SNETNNYGLV QIDGDKVTKL TDFENLKNEY 120
  121 S

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	76.0
Match:	1bglA_
Description:	beta-Galactosidase, domains 2 and 4; beta-Galactosidase; beta-Galactosidase, domain 5; beta-Galactosidase, domain 3
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
glucan 1,3-beta-glucosidase activity	5.16200085143699	bayes_pls_golite062009
beta-glucosidase activity	4.53653290519942	bayes_pls_golite062009
glucosidase activity	3.91964201812391	bayes_pls_golite062009
hydrolase activity, acting on glycosyl bonds	3.79000828866544	bayes_pls_golite062009
hydrolase activity, hydrolyzing O-glycosyl compounds	2.75451815920409	bayes_pls_golite062009
hydrolase activity	2.29984224531667	bayes_pls_golite062009
catalytic activity	1.31308670684647	bayes_pls_golite062009
chitinase activity	0.592310173964326	bayes_pls_golite062009
binding	0.442009020636084	bayes_pls_golite062009
protein binding	0.105573220180415	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [60-70]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NLTDPLADAS V

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [87-207]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RVYTVDNSQD HSHCMKLLQE NGIYLILDVN TPTSAISRYD PACSYNADYL QNVFATIDTF  60
   61 ADYDNVLGFF AGNEVINSVN TTNTATYVKA VVRDMKKYIK ARKYRQIPVG YSAADIVANR 120
  121 Q

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	76.0
Match:	1bglA_
Description:	beta-Galactosidase, domains 2 and 4; beta-Galactosidase; beta-Galactosidase, domain 5; beta-Galactosidase, domain 3
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [329-484]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KVSNPEGNGG YSTSNNYSTC PDYEKGVWEA NNTLPAMPSA ASAYFTSGAG SPMGTGIATQ  60
   61 QSCDAKDDDD EEDDDTSSSS SSSSSSSSSA SSSSESSSST SKASSSSPSA SETSLLKSAA 120
  121 SATSSSQSSS KSKGAAGIIE IPLIFRALAE LYNLVL

[Run NCBI BLAST on this sequence.]

Detection Method:	ORFEUS
Confidence:	9.57
Match:	1ldvA
Description:	No description for 1ldvA was found.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: