YRC Public Data Repository - Protein Structure Prediction

Protein:	MDM12
Organism:	Saccharomyces cerevisiae
Length:	271 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MDM12.

Description	E-value	Query Range	Subject Range
gi\|1654330 - gi\|1654330\|gb\|AAB17867.1\| mitochondrial inheritance component Mdm12p [Saccharomyces cerevisiae]	494.0	[0..1]	[271..1]
MDM12_SCHPO - Mitochondrial distribution and morphology protein 12 OS=Schizosaccharomyces pombe (strain 972 / ATCC... mdm12 - Mdm10 /Mdm12 /Mmm1 complex subunit Mdm12	382.0	[0..1]	[265..1]
MDM12_CANGA - Mitochondrial distribution and morphology protein 12 OS=Candida glabrata GN=MDM12 PE=3 SV=1 MDM12_CANGA - Mitochondrial distribution and morphology protein 12 OS=Candida glabrata (strain ATCC 2001 / CBS 138...	292.0	[0..1]	[268..1]
gi\|1827502 - gi\|1827502\|dbj\|BAA12181.1\| unnamed protein product [Schizosaccharomyces pombe]	263.0	[0..1]	[168..1]
MDM12_ASHGO - Mitochondrial distribution and morphology protein 12 OS=Ashbya gossypii (strain ATCC 10895 / CBS 109... MDM12_ASHGO - Mitochondrial distribution and morphology protein 12 OS=Ashbya gossypii GN=MDM12 PE=3 SV=1	252.0	[0..1]	[269..1]
MDM12_KLULA - Mitochondrial distribution and morphology protein 12 OS=Kluyveromyces lactis GN=MDM12 PE=3 SV=1 MDM12_KLULA - Mitochondrial distribution and morphology protein 12 OS=Kluyveromyces lactis (strain ATCC 8585 / CBS...	240.0	[0..1]	[266..1]
gi\|83766053 - gi\|83766053\|dbj\|BAE56196.1\| unnamed protein product [Aspergillus oryzae] gi\|169767454 - gi\|169767454\|ref\|XP_001818198.1\| hypothetical protein [Aspergillus oryzae RIB40]	150.0	[0..1]	[263..1]
MDM12_CANAL - Mitochondrial distribution and morphology protein 12 OS=Candida albicans (strain SC5314 / ATCC MYA-2... MDM12_CANAL - Mitochondrial distribution and morphology protein 12 OS=Candida albicans GN=MDM12 PE=3 SV=1	139.0	[0..74]	[264..197]
MDM12_YARLI - Mitochondrial distribution and morphology protein 12 OS=Yarrowia lipolytica GN=MDM12 PE=3 SV=1 MDM12_YARLI - Mitochondrial distribution and morphology protein 12 OS=Yarrowia lipolytica (strain CLIB 122 / E 150...	135.0	[0..1]	[264..1]
gi\|50425413, gi\|... - gi\|50425413\|ref\|XP_461300.1\| hypothetical protein DEHA0F23419g [Debaryomyces hansenii CBS767], gi\|49...	128.0	[0..117]	[262..241]

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Predicted Domain #1

Region A:
Residues: [1-181]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSFDINWSTL ESDNRLNDLI RKHLNSYLQN TQLPSYVSNL RVLDFDLGKV GPAITLKEIT  60
   61 DPLDEFYDSI REEADQETEE NNDNKEDSEH ICPDRTIANH EGPKDDFEAP VVMPSPNDIQ 120
  121 FLLEVEYKGD LLVTIGADLV LNYPVEKFMT LPVKLSISDI GLHSLCIVAC LSKQLFLSFL 180
  181 C

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [182-271]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DVSDPALDDN QTVLDPKGPI LAATKPLERI SIVRSMKIET EIGEQYQGQG SVLRSVGELE  60
   61 QFLFTIFKDF LRKELAWPSW INLDFNDGDE

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

		MCM Score	SCOP Match	SCOP Description
View	Download	0.878	c.55.1	Actin-like ATPase domain

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits