YRC Public Data Repository - Protein Structure Prediction

Protein:	PFA4
Organism:	Saccharomyces cerevisiae
Length:	378 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PFA4.

Description	E-value	Query Range	Subject Range
PFA4_YEAST - Palmitoyltransferase PFA4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PFA4 PE=1 SV=1 gi\|151945627 - gi\|151945627\|gb\|EDN63868.1\| palmitoyltransferase [Saccharomyces cerevisiae YJM789] PFA4 - Palmitoyltransferase with autoacylation activity, required for palmitoylation of amino acid permease... gi\|190407339 - gi\|190407339\|gb\|EDV10606.1\| palmitoyltransferase [Saccharomyces cerevisiae RM11-1a]	0.0	[1..378]	[1..378]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	7.0E-50	[9..269]	[7..267]
ZDHC3_MOUSE - Palmitoyltransferase ZDHHC3 OS=Mus musculus GN=Zdhhc3 PE=1 SV=1	5.0E-49	[9..230]	[52..277]
gi\|114586456, gi... - gi\|114586456\|ref\|XP_001146867.1\| PREDICTED: DHHC1 protein isoform 6 [Pan troglodytes], gi\|114586454\|... gi\|119585133, gi... - gi\|206597477\|ref\|NP_001128651.1\| zinc finger, DHHC-type containing 3 isoform 1 [Homo sapiens], gi\|17... gi\|254071545, gi... - gi\|254071547\|gb\|ACT64533.1\| zinc finger, DHHC-type containing 3 protein [synthetic construct], gi\|25...	7.0E-49	[9..230]	[52..277]
ZDH23_ARATH - Probable protein S-acyltransferase 6 OS=Arabidopsis thaliana GN=PAT06 PE=2 SV=1	9.0E-49	[13..257]	[51..325]

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Predicted Domain #1

Region A:
Residues: [1-154]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPVKLRWPWL GIAIPTFLIS FIGYGAHYFI LSNFLSVPKQ ITFEFCLSMI WLSYYLAICT  60
   61 NPGRPLPNYK PPPDIWRNFC KKCQSYKPER SHHCKTCNQC VLMMDHHCPW TMNCVGFANY 120
  121 PHFLRFLFWI IVTTSVLFCI QAKRIYFIWQ QRHL

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	38.408935
Match:	PF01529
Description:	DHHC zinc finger domain

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term	Confidence	Notes
catalytic activity	0.481338897251745	bayes_pls_golite062009
binding	0.0373927717713547	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [155-378]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PGYFFKKSEL IFLTISSPLN SFVLLTITIL FLRCLFNQIL NGRSQIESWD MDRLESLFNS  60
   61 GRLTQKLIDN TWRIYPESRS FQNKKDAEEH LTKKRPRFDE LVNFPYDFDL YTNALLYLGP 120
  121 IHLWLWPYGV PTGDGNNFPK NGISKYEANS SLEDHILSLP WPPDGGKTNT VFNHGSSTIE 180
  181 MRNESGEQLI RTRLPQNGRH ASREKWYNDW GESLDDFGVD VDME

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [258-292]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FPYDFDLYTN ALLYLGPIHL WLWPYGVPTG DGNNF

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4

Region A:
Residues: [293-378]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PKNGISKYEA NSSLEDHILS LPWPPDGGKT NTVFNHGSST IEMRNESGEQ LIRTRLPQNG  60
   61 RHASREKWYN DWGESLDDFG VDVDME

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: