YRC Public Data Repository - Protein Structure Prediction

Protein:	PEX6
Organism:	Saccharomyces cerevisiae
Length:	1030 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PEX6.

Description	E-value	Query Range	Subject Range
PEX6 - AAA-peroxin that heterodimerizes with AAA-peroxin Pex1p and participates in the recycling of peroxis... PEX6_YEAST - Peroxisomal ATPase PEX6 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PEX6 PE=1 SV=1	0.0	[1..1030]	[1..1030]
CDC48_SOYBN - Cell division cycle protein 48 homolog OS=Glycine max GN=CDC48 PE=2 SV=1	0.0	[192..1030]	[4..770]
CD48D_ARATH - Cell division control protein 48 homolog D OS=Arabidopsis thaliana GN=CDC48D PE=1 SV=1	0.0	[190..1030]	[2..768]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	0.0	[201..1030]	[45..802]
CDC48_CAPAN - Cell division cycle protein 48 homolog OS=Capsicum annuum GN=CAFP PE=2 SV=1	0.0	[190..1030]	[2..768]
PEX6_PICAN - Peroxisomal biogenesis factor 6 OS=Pichia angusta GN=PEX6 PE=1 SV=1 PEX6_PICAN - Peroxisomal biogenesis factor 6 OS=Pichia angusta GN=PEX6 PE=1 SV=1	0.0	[57..1029]	[75..1114]
TERA_XENLA - Transitional endoplasmic reticulum ATPase OS=Xenopus laevis GN=vcp PE=1 SV=2	0.0	[196..1030]	[3..765]

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Predicted Domain #1

Region A:
Residues: [1-190]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKASLTFSLS GIYAPCSISR DIYLEYGDKK AECLYGTIRL PQYGPGCTPG KIVHCVLDDS  60
   61 LPFCSIVVPS KLFGFMPTQP TMDFCYFEPI LDNVVPVLDS VTFLINEQLY SKLMDLPQEM 120
  121 QQIQFLHYKY NINSMETVVH SRDILTSGLC QILNCSPFPQ GLVDFTETQL ILVNDTEQKL 180
  181 SALKYANEDE

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [191-305]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EYALPKIGTN SALSIDLESL PCTISRDLLR PAPHINDDNS IYAFTDAETL LRLDVTSGSF  60
   61 ITVSNMGCVR LVKLFVLLLP NGFKKRTIYA PPKIIASFPD CSVVTISKSN IGHTD

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	593.457575
Match:	1e32A_
Description:	Membrane fusion atpase p97 N-terminal domain , P97-Nn; Membrane fusion atpase p97, D1 domain; Membrane fusion atpase p97 domain 2, P97-Nc
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [306-437]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IPIANQVFIS RVGGWLQSQK CFQNIILTTL KKFFSESKRI LCQNDLIPIA FDSSMADLNI  60
   61 AEENDESDDE DELGQYYKND SLVWFFVTSA ELDCFSKDNS HFIIDPNRTK LITTNITNRR 120
  121 PLPLSRSNLQ RY

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	593.457575
Match:	1e32A_
Description:	Membrane fusion atpase p97 N-terminal domain , P97-Nn; Membrane fusion atpase p97, D1 domain; Membrane fusion atpase p97 domain 2, P97-Nc
Matching Structure (courtesy of the PDB):

Predicted Domain #4

Region A:
Residues: [438-618]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YGFAETFYYD LHIFPYVRQL VNILETSFNC SQRGITLNAS VLLHSTTNNV GKATMVRFAS  60
   61 KYLGIHLLEI DCLSLTSNSR QLDSTSKIIG YIRAKCENVL PYASPAVIFL AHLDSILLDV 120
  121 NANQDPEAIK LQKSINFEMS KLLDDFTFKF PGTTFVGSVN NIDNVPSSFR SHMRFEILVP 180
  181 V

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	593.457575
Match:	1e32A_
Description:	Membrane fusion atpase p97 N-terminal domain , P97-Nn; Membrane fusion atpase p97, D1 domain; Membrane fusion atpase p97 domain 2, P97-Nc
Matching Structure (courtesy of the PDB):

Predicted Domain #5

Region A:
Residues: [619-707]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PSEAQRLRIF QWYLSSHELN RDVQQKVPVS YMDNISFSSL SSYSAGLTPL DIKSIVETAR  60
   61 MTATARFYQE SKKCGWLPQS ILITQEDLS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	593.457575
Match:	1e32A_
Description:	Membrane fusion atpase p97 N-terminal domain , P97-Nn; Membrane fusion atpase p97, D1 domain; Membrane fusion atpase p97 domain 2, P97-Nc
Matching Structure (courtesy of the PDB):

Predicted Domain #6

Region A:
Residues: [708-765]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KATSKARNEF SVSIGAPQIP NVTWDDIGGI DFVKGEILDT IDMPLKHPEL FTSGMKKR

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	5.522879
Match:	1iqpA_
Description:	Replication factor C
Matching Structure (courtesy of the PDB):

Predicted Domain #7

Region A:
Residues: [766-883]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SGILFYGPPG TGKTLMAKAI ATNFSLNFFS VKGPELLNMY IGESEANVRR VFQKAREAKP  60
   61 CVIFFDEIDS VAPKRGNQGD SGGVMDRIVS QLLAELDGMS TDADGVFVIG ATNRPDLL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	5.39794
Match:	1d2nA_
Description:	Hexamerization domain of N-ethylmalemide-sensitive fusion (NSF) protein
Matching Structure (courtesy of the PDB):

Predicted Domain #8

Region A:
Residues: [884-1030]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DEALLRPGRF DKLLYLGIPD TDTKQLNILE ALTRKFVLDN DVKLIELAKL CPFNYTGADF  60
   61 YALCSDAMLN AMSRIARMVE KKVSQHNELT GENISTRRWF DKIATKEDTK VVVKMEDFLK 120
  121 AQEQLTPSVS RAELNHYEAV RANFEGA

[Run NCBI BLAST on this sequence.]

Detection Method:	ORFEUS
Confidence:	14.61
Match:	1lv7A
Description:	AAA domain of cell division protein FtsH
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits