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View Structure Prediction Details

Protein: FIG4
Organism: Saccharomyces cerevisiae
Length: 879 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FIG4.

Description E-value Query
Range
Subject
Range
FIG4_MOUSE - Polyphosphoinositide phosphatase OS=Mus musculus GN=Fig4 PE=1 SV=1
819.0 [0..23] [708..5]
gi|110225894, gi... - gi|149027752|gb|EDL83246.1| rCG38206, isoform CRA_b [Rattus norvegicus], gi|114052238|ref|NP_0010405...
815.0 [0..23] [708..5]
gi|44982439, gi|... - gi|45187678|ref|NP_983901.1| ADL195Cp [Ashbya gossypii ATCC 10895], gi|44982439|gb|AAS51725.1| ADL19...
gi|44982439 - gi|44982439|gb|AAS51725.1| ADL195Cp [Ashbya gossypii ATCC 10895]
812.0 [0..21] [764..27]
gi|73973735, gi|... - gi|73973735|ref|XP_532259.2| PREDICTED: similar to SAC domain-containing protein 3 isoform 1 [Canis ...
810.0 [0..23] [708..5]
gi|50308085, gi|... - gi|50308085|ref|XP_454043.1| unnamed protein product [Kluyveromyces lactis], gi|49643178|emb|CAG9913...
gi|49643178 - gi|49643178|emb|CAG99130.1| KLLA0E02113p [Kluyveromyces lactis]
809.0 [0..20] [856..17]
gi|167830421, gi... - gi|167830421|ref|NP_001108096.1| FIG4 homolog [Pan troglodytes], gi|114608993|ref|XP_518683.2| PREDI...
807.0 [0..26] [708..95]
FIG4 - FIG4 homolog, SAC1 lipid phosphatase domain containing (S. cerevisiae)
805.0 [0..23] [708..5]
gi|92096743, gi|... - gi|92096743|gb|AAI14695.1| FIG4 homolog (S. cerevisiae) [Bos taurus], gi|115496568|ref|NP_001069482....
805.0 [0..21] [708..3]

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Predicted Domain #1
Region A:
Residues: [1-95]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNNDAMEHTL GGGILTTSGS KQRKTSKFVM GKYTLYETKD RMYIVGSNKR ETMFRILEID  60
   61 LTVPRGELTV LEDNVFFTRN EIMNVLASLE EATED

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [96-430]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GLHKKITGYG LLGFIKFTCW YYLIMVTKYS QVAVIGGHGI YHIDGIDIIP ITNNYKKPEK  60
   61 SSDEARLLNI FKDLDLTKTF YFSYTYDITN TLQTNILREK LKAVDRCDIT IPCGITDYNE 120
  121 MFVWNNNLLS PIFACIDTVF DWFQCIIHGF IDQVNVSVLG KSIYITLIAR RSHHFAGARF 180
  181 LKRGVNNKGH VANEVETEQI VTDMILTPFH QPGNGFFDSD RYTSFVQHRG SIPLYWTQDA 240
  241 SNLTTKPPIR INVVDPFFSP AALHFDNLFQ RYGGGTIQIL NLIKTKEKTP RETKLLWEFE 300
  301 QCIDYLNEFL PTLKKLDYTS WDMSRASKQD GQGVI

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 184.769551
Match: PF02383
Description: SacI homology domain

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [431-593]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EFLEKYAVNT VTTTGIFHNG PDFASTKIQE GICRSNCIDC LDRTNAAQFV IGKRALGCQL  60
   61 KSLGIIDNSY LEYDSDIVNI LTELFHDLGD TIALQYGGSH LVNTMETYRK INQWSSHSRD 120
  121 MIESIKRFYS NSFVDAQRQD AINLFLGHYS WREGFPSLWE MNT

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.950 N/A N/A a.216.1 Description not found.

Predicted Domain #4
Region A:
Residues: [594-879]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DFYLHNAYSL NMPKRSYIHW WNDYNIKSVK ELINEELIAT GNDVTREKII KNVRGYPGAF  60
   61 DNYWNEYYLP RSVTWIRDLF AYNMNSTRRY HNALSKQDKA MSPFTSRKQS WLNNKLKMIT 120
  121 SSKSLEKAEG RVVETTDLDR DTSPKQELEL YEHYLHIISD RSQKLEEKMN SFSYSKYPIF 180
  181 ISHESSEIPP MRKVIGEPLV DIAEDFTDVY DDDDDGDDEN DEMTTEALLI APDHVSVDEK 240
  241 FYEKVLNVDD YKPALDDYSA VIHIKPDNLQ LYRDLCFSKD IQLDFQ

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle