YRC Public Data Repository - Protein Structure Prediction

Protein:	PHA2
Organism:	Saccharomyces cerevisiae
Length:	368 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PHA2.

Description	E-value	Query Range	Subject Range
PHEA_ENTAG - P-protein OS=Enterobacter agglomerans GN=pheA PE=3 SV=1	3.0E-92	[13..362]	[78..378]
PHEA_SHIFL - P-protein OS=Shigella flexneri GN=pheA PE=3 SV=1 gi\|15832716, gi\|... - gi\|15832716\|ref\|NP_311489.1\| bifunctional chorismate mutase/prephenate dehydratase [Escherichia coli... gi\|24113938, gi\|... - gi\|24113938\|ref\|NP_708448.1\| bifunctional chorismate mutase/prephenate dehydratase [Shigella flexner... gi\|110806734, gi... - gi\|110806734\|ref\|YP_690254.1\| bifunctional chorismate mutase/prephenate dehydratase [Shigella flexne... gi\|238901759, gi... - gi\|238901759\|ref\|YP_002927555.1\| fused chorismate mutase P/prephenate dehydratase [Escherichia coli ... EG10707 - chorismate mutase and prephenate dehydratase, P-protein / Chorismate mutase and prephenate dehydrata... gi\|251785921, gi... - gi\|251785921\|ref\|YP_003000225.1\| hypothetical protein B21_02452 [Escherichia coli BL21], gi\|24237819... gi\|253323551, gi... - gi\|254289330\|ref\|YP_003055078.1\| fused chorismate mutase P/prephenate dehydratase [Escherichia coli ... gi\|30042255, gi\|... - gi\|30063999\|ref\|NP_838170.1\| bifunctional chorismate mutase/prephenate dehydratase [Shigella flexner... gi\|254162569, gi... - gi\|254162569\|ref\|YP_003045677.1\| fused chorismate mutase P/prephenate dehydratase [Escherichia coli ... PHEA_ECO57 - P-protein OS=Escherichia coli O157:H7 GN=pheA PE=3 SV=1 gi\|1800004, gi\|8... - gi\|89109400\|ref\|AP_003180.1\| fused chorismate mutase P and prephenate dehydratase [Escherichia coli ... gi\|254794545, gi... - gi\|254794545\|ref\|YP_003079382.1\| chorismate mutase-P and prephenate dehydratase [Escherichia coli O1... gi\|124527998, gi... - gi\|124527998\|ref\|ZP_01699351.1\| chorismate mutase [Escherichia coli B], gi\|124500890\|gb\|EAY48358.1\| ... gi\|168801716, gi... - gi\|189376177\|gb\|EDU94593.1\| chorismate mutase/prephenate dehydratase [Escherichia coli O157:H7 str. ... gi\|189370904, gi... - gi\|189370904\|gb\|EDU89320.1\| chorismate mutase/prephenate dehydratase [Escherichia coli O157:H7 str. ... gi\|170082203, gi... - gi\|170082203\|ref\|YP_001731523.1\| bifunctional chorismate mutase P and prephenate dehydratase [Escher... EG10707 - chorismate mutase and prephenate dehydratase, P-protein / Chorismate mutase and prephenate dehydrata... gi\|169754052, gi... - gi\|170019124\|ref\|YP_001724078.1\| bifunctional chorismate mutase/prephenate dehydratase [Escherichia ... gi\|195940193 - gi\|195940193\|ref\|ZP_03085575.1\| bifunctional chorismate mutase/prephenate dehydratase [Escherichia c... gi\|194416646, gi... - gi\|194435115\|ref\|ZP_03067351.1\| chorismate mutase/prephenate dehydratase [Shigella dysenteriae 1012]... gi\|208733388, gi... - gi\|208812111\|ref\|ZP_03253440.1\| P-protein [Escherichia coli O157:H7 str. EC4045], gi\|208733388\|gb\|ED... gi\|208806829, gi... - gi\|208806829\|ref\|ZP_03249166.1\| P-protein [Escherichia coli O157:H7 str. EC4206], gi\|208726630\|gb\|ED... gi\|189354540, gi... - gi\|189354540\|gb\|EDU72959.1\| chorismate mutase/prephenate dehydratase [Escherichia coli O157:H7 str. ... gi\|188014013, gi... - gi\|188014013\|gb\|EDU52135.1\| chorismate mutase/prephenate dehydratase [Escherichia coli O157:H7 str. ... gi\|168771704, gi... - gi\|189359604\|gb\|EDU78023.1\| chorismate mutase/prephenate dehydratase [Escherichia coli O157:H7 str. ... gi\|189367221, gi... - gi\|189367221\|gb\|EDU85637.1\| chorismate mutase/prephenate dehydratase [Escherichia coli O157:H7 str. ... gi\|189003474, gi... - gi\|189003474\|gb\|EDU72460.1\| chorismate mutase/prephenate dehydratase [Escherichia coli O157:H7 str. ... gi\|187770623, gi... - gi\|187770623\|gb\|EDU34467.1\| chorismate mutase/prephenate dehydratase [Escherichia coli O157:H7 str. ... gi\|157162073, gi... - gi\|75196612\|ref\|ZP_00706682.1\| COG0077: Prephenate dehydratase [Escherichia coli HS], gi\|157162073\|r... gi\|209160459, gi... - gi\|209399059\|ref\|YP_002272070.1\| P-protein [Escherichia coli O157:H7 str. EC4115], gi\|209160459\|gb\|A... gi\|208821481, gi... - gi\|208821481\|ref\|ZP_03261801.1\| P-protein [Escherichia coli O157:H7 str. EC4042], gi\|208741604\|gb\|ED... gi\|217326797, gi... - gi\|217326797\|ref\|ZP_03442880.1\| P-protein [Escherichia coli O157:H7 str. TW14588], gi\|217319164\|gb\|E... PHEA_ECOLI - P-protein [Includes: Chorismate mutase (EC 5.4.99.5) (CM); Prephenate dehydratase (EC 4.2.1.51) (PDT... gi\|194421707, gi... - gi\|83585233\|ref\|ZP_00923882.1\| COG0077: Prephenate dehydratase [Escherichia coli 101-1], gi\|19443934...	8.0E-91	[13..362]	[78..378]
gi\|25292745 - gi\|25292745\|pir\|\|B85906 chorismate mutase-P and prephenate dehydratase [imported] - Escherichia coli... gi\|12517021, gi\|... - gi\|15803121\|ref\|NP_289152.1\| bifunctional chorismate mutase/prephenate dehydratase [Escherichia coli...	1.0E-90	[13..362]	[78..378]
PHEA_PSEST - P-protein OS=Pseudomonas stutzeri GN=pheA PE=3 SV=2	6.0E-89	[15..362]	[66..363]
lcl\|NC_016856.1_... - [gene=pheA] [protein=bifunctional chorismate mutase/prephenate dehydratase] [protein_id=YP_005238788... gi\|204929691, gi... - gi\|204929691\|ref\|ZP_03220765.1\| P-protein [Salmonella enterica subsp. enterica serovar Javiana str. ... gi\|224469047, gi... - gi\|224584520\|ref\|YP_002638318.1\| chorismate mutase-P/prephenate dehydratase [Salmonella enterica sub... gi\|194735195, gi... - gi\|194735195\|ref\|YP_002115676.1\| P-protein [Salmonella enterica subsp. enterica serovar Schwarzengru... gi\|197215366, gi... - gi\|197251663\|ref\|YP_002147602.1\| P-protein [Salmonella enterica subsp. enterica serovar Agona str. S... gi\|194410082, gi... - gi\|194451778\|ref\|YP_002046671.1\| bifunctional chorismate mutase/prephenate dehydratase [Salmonella e... gi\|194457294, gi... - gi\|194470930\|ref\|ZP_03076914.1\| P-protein [Salmonella enterica subsp. enterica serovar Kentucky str.... gi\|195633269, gi... - gi\|195633269\|gb\|EDX51683.1\| P-protein [Salmonella enterica subsp. enterica serovar Newport str. SL31... gi\|194403833, gi... - gi\|194445170\|ref\|YP_002041929.1\| P-protein [Salmonella enterica subsp. enterica serovar Newport str.... gi\|168239435, gi... - gi\|197287848\|gb\|EDY27236.1\| P-protein [Salmonella enterica subsp. enterica serovar Schwarzengrund st... gi\|168244688, gi... - gi\|205336471\|gb\|EDZ23235.1\| P-protein [Salmonella enterica subsp. enterica serovar Heidelberg str. S... gi\|167992445, gi... - gi\|205329325\|gb\|EDZ16089.1\| P-protein [Salmonella enterica subsp. enterica serovar 4,[5],12:i:- str.... gi\|205331834, gi... - gi\|205331834\|gb\|EDZ18598.1\| P-protein [Salmonella enterica subsp. enterica serovar Kentucky str. CDC... gi\|16765982, gi\|... - gi\|16765982\|ref\|NP_461597.1\| bifunctional chorismate mutase/prephenate dehydratase [Salmonella typhi... gi\|62128872, gi\|... - gi\|62181239\|ref\|YP_217656.1\| bifunctional chorismate mutase/prephenate dehydratase [Salmonella enter...	3.0E-88	[13..362]	[78..378]
gi\|29142991, gi\|... - gi\|29142991\|ref\|NP_806333.1\| bifunctional chorismate mutase/prephenate dehydratase [Salmonella enter... gi\|213622692 - gi\|213622692\|ref\|ZP_03375475.1\| bifunctional chorismate mutase/prephenate dehydratase [Salmonella en... gi\|16761520 - gi\|16761520\|ref\|NP_457137.1\| bifunctional chorismate mutase/prephenate dehydratase [Salmonella enter... gi\|213580478 - gi\|213580478\|ref\|ZP_03362304.1\| bifunctional chorismate mutase/prephenate dehydratase [Salmonella en... gi\|213424872 - gi\|213424872\|ref\|ZP_03357622.1\| bifunctional chorismate mutase/prephenate dehydratase [Salmonella en... gi\|25292746, gi\|... - gi\|25292746\|pir\|\|AG0832 prephenate dehydratase (EC 4.2.1.51) - Salmonella enterica subsp. enterica s... gi\|213161004 - gi\|213161004\|ref\|ZP_03346714.1\| bifunctional chorismate mutase/prephenate dehydratase [Salmonella en... gi\|213999725 - gi\|213999725\|ref\|ZP_03410460.1\| bifunctional chorismate mutase/prephenate dehydratase [Salmonella en... gi\|213646595 - gi\|213646595\|ref\|ZP_03376648.1\| bifunctional chorismate mutase/prephenate dehydratase [Salmonella en...	8.0E-88	[13..362]	[78..378]
gi\|254241854, gi... - gi\|84326074\|ref\|ZP_00974104.1\| COG0077: Prephenate dehydratase [Pseudomonas aeruginosa 2192], gi\|254... gi\|126168059, gi... - gi\|84319993\|ref\|ZP_00968379.1\| COG0077: Prephenate dehydratase [Pseudomonas aeruginosa C3719], gi\|25... PHEA_PSEAE - P-protein OS=Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228) GN=pheA PE... gi\|107102696 - gi\|107102696\|ref\|ZP_01366614.1\| hypothetical protein PaerPA_01003762 [Pseudomonas aeruginosa PACS2] PHEA_PSEAE - P-protein OS=Pseudomonas aeruginosa GN=pheA PE=3 SV=1 gi\|116051155, gi... - gi\|46164072\|ref\|ZP_00204964.1\| COG0077: Prephenate dehydratase [Pseudomonas aeruginosa UCBPP-PA14], ...	3.0E-87	[16..362]	[67..363]
AROD4_ARATH - Arogenate dehydratase 4, chloroplastic OS=Arabidopsis thaliana GN=ADT4 PE=1 SV=1	3.0E-86	[1..360]	[90..410]
gi\|42631447 - gi\|42631447\|ref\|ZP_00156985.1\| COG0077: Prephenate dehydratase [Haemophilus influenzae R2866] PHEA_HAEIN - P-protein OS=Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) GN=pheA PE=3 SV=1 gi\|145639335, gi... - gi\|145639335\|ref\|ZP_01794941.1\| chorismate mutase/prephenate dehydratase [Haemophilus influenzae Pit... PHEA_HAEIN - P-protein OS=Haemophilus influenzae GN=pheA PE=4 SV=1 gi\|144979660, gi... - gi\|145627885\|ref\|ZP_01783686.1\| chorismate mutase/prephenate dehydratase [Haemophilus influenzae 22....	2.0E-85	[13..363]	[78..379]

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Predicted Domain #1

Region A:
Residues: [1-45]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKIKILVDEY NTQKEQAKKV RKATSLYFRI HPSIMASKTL RVLFL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	3.30103
Match:	1ecmA_
Description:	Chorismate mutase domain of P-protein
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [46-260]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GPKGTYSHQA ALQQFQSTSD VEYLPAASIP QCFNQLENDT SIDYSVVPLE NSTNGQVVFS  60
   61 YDLLRDRMIK KALSLPAPAD TNRITPDIEV IAEQYVPITH CLISPIQLPN GIASLGNFEE 120
  121 VIIHSHPQVW GQVECYLRSM AEKFPQVTFI RLDCSSTSES VNQCIRSSTA DCDNILHLAI 180
  181 ASETAAQLHK AYIIEHSIND KLGNTTRFLV LKRRE

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	10.677781
Match:	PF00800
Description:	Prephenate dehydratase

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [261-368]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NAGDNEVEDT GLLRVNLLTF TTRQDDPGSL VDVLNILKIH SLNMCSINSR PFHLDEHDRN  60
   61 WRYLFFIEYY TEKNTPKNKE KFYEDISDKS KQWCLWGTFP RNERYYHK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	15.39794
Match:	1in9A_
Description:	No description for 1in9A_ was found.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits