YRC Public Data Repository - Protein Structure Prediction

Protein:	ERG24
Organism:	Saccharomyces cerevisiae
Length:	438 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ERG24.

Description	E-value	Query Range	Subject Range
gi\|19527034, gi\|... - gi\|27502750\|gb\|AAH42522.1\| Lbr protein [Mus musculus], gi\|19527034\|ref\|NP_598576.1\| lamin B receptor...	0.0	[7..438]	[213..626]
gi\|168277676 - gi\|168277676\|dbj\|BAG10816.1\| lamin-B receptor [synthetic construct] gi\|119590148, gi... - gi\|439434\|gb\|AAA59495.1\| integral nuclear envelope inner membrane protein [Homo sapiens], gi\|1890533...	0.0	[8..438]	[203..615]
LBR_RAT - Lamin-B receptor OS=Rattus norvegicus GN=Lbr PE=1 SV=1	0.0	[7..438]	[207..620]
gi\|545906 - gi\|545906\|gb\|AAB30203.1\| sterol delta 14 reductase; Erg24p [Saccharomyces cerevisiae]	0.0	[1..438]	[1..438]
LBR_CHICK - Lamin-B receptor OS=Gallus gallus GN=LBR PE=1 SV=1	0.0	[6..431]	[194..601]
ERG24_FUSSO - Delta(14)-sterol reductase OS=Fusarium solani subsp. pisi PE=3 SV=1 gi\|1134869, gi\|3... - sp\|Q01447\|ER24_FUSSO Delta(14)-sterol reductase (C-14 sterol reductase) (Sterol C14-reductase), gi\|1...	0.0	[3..438]	[7..485]
ERG24_NEUCR - Delta(14)-sterol reductase OS=Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1... ER24_NEUCR, ERG2... - Delta(14)-sterol reductase OS=Neurospora crassa GN=erg-3 PE=3 SV=1, (P38670) Delta(14)-sterol reduct...	0.0	[2..438]	[11..490]
gi\|147907078, gi... - gi\|4995923\|emb\|CAB44317.1\| lamin B receptor [Xenopus laevis], gi\|147907078\|ref\|NP_001079301.1\| lamin...	0.0	[6..438]	[211..620]

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Predicted Domain #1

Region A:
Residues: [1-438]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVSALNPRTT EFEFGGLIGA LGISIGLPVF TIILNQMIRP DYFIKGFFQN FDIVELWNGI  60
   61 KPLRYYLGNR ELWTVYCLWY GILAVLDVIL PGRVMKGVQL RDGSKLSYKI NGIAMSTTLV 120
  121 LVLAIRWKLT DGQLPELQYL YENHVSLCII SILFSFFLAT YCYVASFIPL IFKKNGNGKR 180
  181 EKILALGGNS GNIIYDWFIG RELNPRLGPL DIKMFSELRP GMLLWLLINL SCLHHHYLKT 240
  241 GKINDALVLV NFLQGFYIFD GVLNEEGVLT MMDITTDGFG FMLAFGDLSL VPFTYSLQAR 300
  301 YLSVSPVELG WVKVVGILAI MFLGFHIFHS ANKQKSEFRQ GKLENLKSIQ TKRGTKLLCD 360
  361 GWWAKSQHIN YFGDWLISLS WCLATWFQTP LTYYYSLYFA TLLLHRQQRD EHKCRLKYGE 420
  421 NWEEYERKVP YKIIPYVY

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	299.619789
Match:	PF01222
Description:	Ergosterol biosynthesis ERG4/ERG24 family

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits