YRC Public Data Repository - Protein Structure Prediction

Protein:	GOR1
Organism:	Saccharomyces cerevisiae
Length:	350 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GOR1.

Description	E-value	Query Range	Subject Range
SERA_METJA - D-3-phosphoglycerate dehydrogenase OS=Methanocaldococcus jannaschii GN=serA PE=3 SV=1 SERA_METJA - D-3-phosphoglycerate dehydrogenase OS=Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / ...	0.0	[7..349]	[2..327]
GYAR_PYRFU - Glyoxylate reductase OS=Pyrococcus furiosus GN=gyaR PE=3 SV=1 GYAR_PYRFU - Glyoxylate reductase OS=Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1) GN=gyaR ...	8.0E-97	[3..348]	[1..331]
gi\|16758046, gi\|... - gi\|16758046\|ref\|NP_445787.1\| C-terminal binding protein 2 [Rattus norvegicus], gi\|149061321\|gb\|EDM11...	2.0E-96	[1..349]	[573..911]
GYAR_THELI - Glyoxylate reductase OS=Thermococcus litoralis GN=gyaR PE=1 SV=1 GYAR_THELN - Glyoxylate reductase OS=Thermococcus litoralis (strain ATCC 51850 / DSM 5473 / JCM 8560 / NS-C) GN=g...	2.0E-96	[3..348]	[1..331]
SERA_ARCFU - D-3-phosphoglycerate dehydrogenase OS=Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 /... SERA_ARCFU - D-3-phosphoglycerate dehydrogenase OS=Archaeoglobus fulgidus GN=serA PE=3 SV=1	1.0E-95	[9..350]	[3..328]
gi\|18858481, gi\|... - gi\|18858481\|ref\|NP_571790.1\| C-terminal binding protein 2 [Danio rerio], gi\|11933135\|dbj\|BAB19679.1\|...	4.0E-95	[1..349]	[30..368]
gi\|14601656, gi\|... - gi\|5105521\|dbj\|BAA80834.1\| 347aa long hypothetical D-3-phosphoglycerate dehydrogenase [Aeropyrum per... gi\|7431353 - pir\|\|E72568 probable D-3-phosphoglycerate dehydrogenase APE1831 - Aeropyrum pernix (strain K1)	2.0E-94	[3..348]	[14..345]
gi\|28372481, gi\|... - gi\|28372481\|ref\|NP_783643.1\| C-terminal binding protein 2 [Bos taurus], gi\|12034659\|gb\|AAG45953.1\|AF...	4.0E-94	[1..349]	[567..905]
gi\|7431368 - gi\|7431368\|pir\|\|H69229 phosphoglycerate dehydrogenase - Methanobacterium thermoautotrophicum (strain... SERA_METTH - D-3-phosphoglycerate dehydrogenase OS=Methanothermobacter thermautotrophicus (strain ATCC 29096 / DS...	6.0E-94	[1..350]	[1..329]
gi\|12746590, gi\|... - gi\|12746590\|ref\|NP_073713.1\| C-terminal binding protein 2 isoform 2 [Homo sapiens], gi\|12034653\|gb\|A...	6.0E-94	[1..349]	[570..908]

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Predicted Domain #1

Region A:
Residues: [1-114]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSKKPIVLKL GKDAFGDQAW GELEKIADVI TIPESTTREQ FLREVKDPQN KLSQVQVITR  60
   61 TARSVKNTGR FDEELALALP SSVVAVCHTG AGYDQIDVEP FKKRHIQVAN VPDL

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [306-350]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SVETRKKMEE LVVENAKNVI LTGKVLTIVP ELQNEDWPNE SKPLV

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	377.0103
Match:	1gdhA_
Description:	D-glycerate dehydrogenase
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [115-305]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VSNATADTHV FLLLGALRNF GIGNRRLIEG NWPEAGPACG SPFGYDPEGK TVGILGLGRI  60
   61 GRCILERLKP FGFENFIYHN RHQLPSEEEH GCEYVGFEEF LKRSDIVSVN VPLNHNTHHL 120
  121 INAETIEKMK DGVVIVNTAR GAVIDEQAMT DALRSGKIRS AGLDVFEYEP KISKELLSMS 180
  181 QVLGLPHMGT H

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	377.0103
Match:	1gdhA_
Description:	D-glycerate dehydrogenase
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits