| Protein: | PIK1 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 1066 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PIK1.
| Description | E-value | Query Range |
Subject Range |
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0.0 | [1..1066] | [1..1066] |
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0.0 | [11..1066] | [2..977] |
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0.0 | [10..1064] | [24..1120] |
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0.0 | [276..1019] | [3179..4023] |
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0.0 | [276..1019] | [3178..3991] |
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Region A: Residues: [1-121] |
1 11 21 31 41 51
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1 MHKASSSKKS FDDTIELKKN EQLLKLINSS EFTLHNCVEL LCKHSENIGI HYYLCQKLAT 60
61 FPHSELQFYI PQLVQVLVTM ETESMALEDL LLRLRAENPH FALLTFWQLQ ALLTDLSTDP 120
121 A
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| Detection Method: |  |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.554 | 0.170 | ascospore formation | a.118.1 | ARM repeat |
| View | Download | 0.597 | 0.021 | ascospore formation | a.85.1 | Hemocyanin, N-terminal domain |
| View | Download | 0.674 | 0.008 | ascospore formation | a.118.11 | Cytochrome c oxidase subunit E |
| View | Download | 0.524 | 0.006 | ascospore formation | a.60.5 | Barrier-to-autointegration factor, BAF |
| View | Download | 0.674 | N/A | N/A | a.118.11 | Cytochrome c oxidase subunit E |
| View | Download | 0.620 | N/A | N/A | a.118.11 | Cytochrome c oxidase subunit E |
| View | Download | 0.597 | N/A | N/A | a.85.1 | Hemocyanin, N-terminal domain |
| View | Download | 0.554 | N/A | N/A | a.118.1 | ARM repeat |
| View | Download | 0.524 | N/A | N/A | a.60.5 | Barrier-to-autointegration factor, BAF |
| View | Download | 0.517 | N/A | N/A | a.118.1 | ARM repeat |
| View | Download | 0.490 | N/A | N/A | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.459 | N/A | N/A | a.118.9 | ENTH/VHS domain |
| View | Download | 0.422 | N/A | N/A | a.80.1 | DNA polymerase III clamp loader subunits, C-terminal domain |
| View | Download | 0.406 | N/A | N/A | a.80.1 | DNA polymerase III clamp loader subunits, C-terminal domain |
| View | Download | 0.406 | N/A | N/A | a.85.1 | Hemocyanin, N-terminal domain |
| View | Download | 0.382 | N/A | N/A | a.78.1 | Fatty acid responsive transcription factor FadR, C-terminal domain |
| View | Download | 0.378 | N/A | N/A | a.95.1 | Influenza virus matrix protein M1 |
| View | Download | 0.377 | N/A | N/A | a.118.9 | ENTH/VHS domain |
| View | Download | 0.366 | N/A | N/A | a.22.1 | Histone-fold |
| View | Download | 0.359 | N/A | N/A | d.87.1 | FAD/NAD-linked reductases, dimerisation (C-terminal) domain |
| View | Download | 0.355 | N/A | N/A | a.3.1 | Cytochrome c |
| View | Download | 0.339 | N/A | N/A | a.118.13 | Arp2/3 complex 16 kDa subunit ARPC5 |
| View | Download | 0.335 | N/A | N/A | d.110.4 | SNARE-like |
| View | Download | 0.333 | N/A | N/A | d.14.1 | Ribosomal protein S5 domain 2-like |
| View | Download | 0.331 | N/A | N/A | a.52.1 | Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin |
| View | Download | 0.331 | N/A | N/A | a.118.8 | TPR-like |
| View | Download | 0.328 | N/A | N/A | d.58.39 | Glutamyl tRNA-reductase catalytic, N-terminal domain |
| View | Download | 0.320 | N/A | N/A | a.79.1 | Antitermination factor NusB |
| View | Download | 0.315 | N/A | N/A | a.118.8 | TPR-like |
| View | Download | 0.301 | N/A | N/A | a.1.1 | Globin-like |
| View | Download | 0.294 | N/A | N/A | a.118.18 | Cysteine rich protein B (HcpB) |
| View | Download | 0.293 | N/A | N/A | a.74.1 | Cyclin-like |
| View | Download | 0.286 | N/A | N/A | a.1.1 | Globin-like |
| View | Download | 0.280 | N/A | N/A | d.54.1 | Enolase N-terminal domain-like |
| View | Download | 0.278 | N/A | N/A | a.18.1 | T4 endonuclease V |
| View | Download | 0.273 | N/A | N/A | f.1.4 | Bcl-2 inhibitors of programmed cell death |
| View | Download | 0.268 | N/A | N/A | a.23.2 | Diol dehydratase, gamma subunit |
| View | Download | 0.267 | N/A | N/A | d.224.1 | SufE-like |
| View | Download | 0.263 | N/A | N/A | d.74.4 | Prokaryotic AspRS, insert domain |
| View | Download | 0.262 | N/A | N/A | a.70.1 | N-terminal domain of the delta subunit of the F1F0-ATP synthase |
| View | Download | 0.260 | N/A | N/A | a.84.1 | Scaffolding protein gpD of bacteriophage procapsid |
| View | Download | 0.249 | N/A | N/A | f.1.4 | Bcl-2 inhibitors of programmed cell death |
| View | Download | 0.247 | N/A | N/A | a.1.1 | Globin-like |
| View | Download | 0.244 | N/A | N/A | c.45.1 | (Phosphotyrosine protein) phosphatases II |
| View | Download | 0.239 | N/A | N/A | a.118.1 | ARM repeat |
| View | Download | 0.238 | N/A | N/A | a.118.12 | Ran-GTPase activating protein 1 (RanGAP1), C-terminal domain |
| View | Download | 0.235 | N/A | N/A | b.81.1 | Trimeric LpxA-like enzymes |
| View | Download | 0.234 | N/A | N/A | a.60.8 | HRDC-like |
| View | Download | 0.233 | N/A | N/A | a.65.1 | Annexin |
| View | Download | 0.232 | N/A | N/A | a.118.8 | TPR-like |
| View | Download | 0.228 | N/A | N/A | a.118.1 | ARM repeat |
| View | Download | 0.227 | N/A | N/A | a.73.1 | Retrovirus capsid protein, N-terminal core domain |
| View | Download | 0.223 | N/A | N/A | a.118.9 | ENTH/VHS domain |
| View | Download | 0.219 | N/A | N/A | d.108.1 | Acyl-CoA N-acyltransferases (Nat) |
| View | Download | 0.217 | N/A | N/A | d.51.1 | Eukaryotic type KH-domain (KH-domain type I) |
| View | Download | 0.214 | N/A | N/A | a.60.13 | Putative methyltransferase TM0872, insert domain |
| View | Download | 0.212 | N/A | N/A | a.73.1 | Retrovirus capsid protein, N-terminal core domain |
| View | Download | 0.210 | N/A | N/A | a.77.1 | DEATH domain |
| View | Download | 0.209 | N/A | N/A | a.46.1 | Methionine synthase domain |
| View | Download | 0.204 | N/A | N/A | c.64.1 | Pyruvate-ferredoxin oxidoreductase, PFOR, domain III |
| View | Download | 0.201 | N/A | N/A | a.72.1 | Functional domain of the splicing factor Prp18 |
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Region A: Residues: [122-434] |
1 11 21 31 41 51
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1 SYGFQVARRV LNNLQTNLFN TSSGSDKNVK IHENVAPALV LSSMIMSAIA FPQLSEVTKP 60
61 LVESQGRRQK AFVFKLARSA MKDFTKNMTL KNTLLNKKTS RSKRVSSNRS STPTSPIDLI 120
121 DPIKTKEDAS FRKSRHSEVK LDFDIVDDIG NQVFEERISS SIKLPKRKPK YLDNSYVHRT 180
181 YDGKNINRDG SISNTAKALD GNKGDYISPK GRNDENNEIG NNEDETGGET EEDADALNSD 240
241 HFTSSMPDLH NIQPRTSSAS SASLEGTPKL NRTNSQPLSR QAFKNSKKAN SSLSQEIDLS 300
301 QLSTTSKIKM LKA
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| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
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Region A: Residues: [435-692] |
1 11 21 31 41 51
| | | | | |
1 NYFRCETQFA IALETISQRL ARVPTEARLS ALRAELFLLN RDLPAEVDIP TLLPPNKKGK 60
61 LHKLVTITAN EAQVLNSAEK VPYLLLIEYL RDEFDFDPTS ETNERLLKKI SGNQGGLIFD 120
121 LNYMNRKENN ENRNESTLTS NNTRSSVYDS NSFNNGASRN EGLSSTSRSD SASTAHVRTE 180
181 VNKEEDLGDM SMVKVRNRTD DEAYRNALVI QSAANVPILP DDSQDRSPEL NFGSNLDEVL 240
241 IENGINSKNI HSQTDALA
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| Detection Method: | |
| Confidence: | 319.9897 |
| Match: | 1e8yA_ |
| Description: | Phoshoinositide 3-kinase (PI3K) helical domain; Phoshoinositide 3-kinase (PI3K); Phoshoinositide 3-kinase (PI3K), catalytic domain |
Matching Structure (courtesy of the PDB): |
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Region A: Residues: [693-846] |
1 11 21 31 41 51
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1 DQMRVSAVML AQLDKSPQQL SESTKQIRAQ IISSMKEVQD KFGYHDLEAL HGMAGERKLE 60
61 NDLMTGGIDT SYLGEDWATK KERIRKTSEY GHFENWDLCS VIAKTGDDLR QEAFAYQMIQ 120
121 AMANIWVKEK VDVWVKRMKI LITSANTGLV ETIT
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Region B: Residues: [989-1019] |
1 11 21 31 41 51
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1 KYADQIVSMC EIMQKDNMQP CFDAGEQTSV Q
|
| Detection Method: | |
| Confidence: | 319.9897 |
| Match: | 1e8yA_ |
| Description: | Phoshoinositide 3-kinase (PI3K) helical domain; Phoshoinositide 3-kinase (PI3K); Phoshoinositide 3-kinase (PI3K), catalytic domain |
| Matching Structure (courtesy of the PDB): |
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Region A: Residues: [847-988] |
1 11 21 31 41 51
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1 NAMSVHSIKK ALTKKMIEDA ELDDKGGIAS LNDHFLRAFG NPNGFKYRRA QDNFASSLAA 60
61 YSVICYLLQV KDRHNGNIMI DNEGHVSHID FGFMLSNSPG SVGFEAAPFK LTYEYIELLG 120
121 GVEGEAFKKF VELTKSSFKA LR
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Region B: Residues: [1020-1066] |
1 11 21 31 41 51
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1 LRQRFQLDLS EKEVDDFVEN FLIGKSLGSI YTRIYDQFQL ITQGIYS
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| Detection Method: | |
| Confidence: | 319.9897 |
| Match: | 1e8yA_ |
| Description: | Phoshoinositide 3-kinase (PI3K) helical domain; Phoshoinositide 3-kinase (PI3K); Phoshoinositide 3-kinase (PI3K), catalytic domain |
| Matching Structure (courtesy of the PDB): |
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