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View Structure Prediction Details

Protein: MRPL17
Organism: Saccharomyces cerevisiae
Length: 281 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MRPL17.

Description E-value Query
Range
Subject
Range
gi|190409226 - gi|190409226|gb|EDV12491.1| 60S ribosomal protein L17, mitochondrial precursor [Saccharomyces cerevi...
MRPL17 - Mitochondrial ribosomal protein of the large subunit
RM17_YEAST - 54S ribosomal protein L17, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN...
1.0E-96 [1..281] [1..281]
MRPL46 - mitochondrial ribosomal protein L46
2.0E-77 [9..280] [30..278]
mrpl17 - mitochondrial ribosomal protein subunit L17
RM17_SCHPO - 54S ribosomal protein L17, mitochondrial OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=m...
1.0E-72 [2..280] [17..266]
RM46_MOUSE - 39S ribosomal protein L46, mitochondrial OS=Mus musculus GN=Mrpl46 PE=1 SV=1
7.0E-68 [9..281] [28..277]
gi|220947842, gi... - gi|220957220|gb|ACL91153.1| mRpL46-PA [synthetic construct], gi|220947842|gb|ACL86464.1| mRpL46-PA [...
mRpL46-PA - The gene mitochondrial ribosomal protein L46 is referred to in FlyBase by the symbol Dmel\mRpL46 (CG...
2.0E-59 [9..279] [11..258]
gi|24111323, gi|... - gi|24111323|gb|AAN46785.1| At1g14620/T5E21_15 [Arabidopsis thaliana], gi|22022540|gb|AAM83228.1| At1...
5.0E-47 [124..273] [69..229]

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Predicted Domain #1
Region A:
Residues: [1-143]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKVNLMLKRG LATATATASS APPKIKVGVL LSRIPIIKSE LNELEKKYYE YQSELEKRLM  60
   61 WTFPAYFYFK KGTVAEHKFL SLQKGPISKK NGIWFPRGIP DIKHGRERST KQEVKLSDDS 120
  121 TVAFSNNQKE QSKDDVNRPV IPN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.346 c.47.1 Thioredoxin-like

Predicted Domain #2
Region A:
Residues: [144-281]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DRITEADRSN DMKSLERQLS RTLYLLVKDK SGTWKFPNFD LSDESKPLHV HAENELKLLS  60
   61 GDQIYTWSVS ATPIGVLQDE RNRTAEFIVK SHILAGKFDL VASKNDAFED FAWLTKGEIS 120
  121 EYVPKDYFNK TEFLLADN

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 7.74
Match: 1kt9A
Description: Diadenosine tetraphosphate hydrolase (Ap4A hydrolase)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 1.38338559299412 bayes_pls_golite062009
binding 0.881558273069274 bayes_pls_golite062009
nucleic acid binding 0.495924061190848 bayes_pls_golite062009
RNA binding 0.44030858339937 bayes_pls_golite062009
protein binding 0.358912650308843 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle