YRC Public Data Repository - Protein Structure Prediction

Protein:	CWC25
Organism:	Saccharomyces cerevisiae
Length:	179 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CWC25.

Description	E-value	Query Range	Subject Range
CWC25 - Heat-stable protein required for the first step of pre-mRNA splicing; component of a complex contain... CWC25_YEAST - Pre-mRNA-splicing factor CWC25 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=CWC25 PE=...	8.0E-54	[1..179]	[1..179]
Y4919_ARATH - Uncharacterized zinc finger CCHC domain-containing protein At4g19190 OS=Arabidopsis thaliana GN=At4g...	3.0E-37	[4..132]	[41..167]
CWC25_SCHPO - Pre-mRNA-splicing factor cwf25 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=cwf25 PE=1 ... cwf25 - complexed with Cdc5 protein Cwf25	1.0E-24	[1..152]	[1..149]
Cwc25-PA - The gene Cwc25 is referred to in FlyBase by the symbol Dmel\Cwc25 (CG2843, FBgn0031452). It is a pro...	6.0E-20	[1..97]	[1..96]
CWC25 - CWC25 spliceosome-associated protein homolog (S. cerevisiae)	2.0E-19	[1..96]	[1..90]
gi\|21312952, gi\|... - gi\|21312952\|ref\|NP_080462.1\| coiled-coil domain containing 49 [Mus musculus], gi\|12836581\|dbj\|BAB237...	5.0E-19	[1..96]	[1..90]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	6.0E-18	[1..85]	[1..77]

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Predicted Domain #1

Region A:
Residues: [1-179]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGSGDLNLLK SWNPKLMKNR KKVWETEQDL ITEQQKLNTR LKEIEKEREL NELLNESSKD  60
   61 KPETLKNDLA LKKSGLEWMY QDAKLSDEKE DYLLGKKKLD SSILNQPATP PVRAATTISA 120
  121 SGAATSISSQ KKKSKLLKDD PMSKFKVTKQ QRRTPDSTKK RAMSQRGKPL SKPAPDLDY

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits