YRC Public Data Repository - Protein Structure Prediction

Protein:	SUI1
Organism:	Saccharomyces cerevisiae
Length:	108 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SUI1.

Description	E-value	Query Range	Subject Range
SUI1_ANOGA - Protein translation factor SUI1 homolog OS=Anopheles gambiae GN=AGAP006459 PE=3 SV=1 gi\|58388730, gi\|... - gi\|58388730\|ref\|XP_316499.2\| AGAP006459-PA [Anopheles gambiae str. PEST], gi\|55239229\|gb\|EAA11885.2\|...	1.0E-34	[1..108]	[1..110]
gi\|198151109, gi... - gi\|198463085\|ref\|XP_002135439.1\| GA28326 [Drosophila pseudoobscura pseudoobscura], gi\|198151109\|gb\|E... gi\|220948056, gi... - gi\|220957264\|gb\|ACL91175.1\| CG17737-PA [synthetic construct], gi\|220948056\|gb\|ACL86571.1\| CG17737-PA... gi\|194128264, gi... - gi\|195337106\|ref\|XP_002035171.1\| GM14550 [Drosophila sechellia], gi\|194128264\|gb\|EDW50307.1\| GM14550... gi\|194141875, gi... - gi\|195402981\|ref\|XP_002060077.1\| GJ15457 [Drosophila virilis], gi\|194141875\|gb\|EDW58288.1\| GJ15457 [... gi\|195428650, gi... - gi\|195428650\|ref\|XP_002062382.1\| GK17510 [Drosophila willistoni], gi\|194158467\|gb\|EDW73368.1\| GK1751... gi\|194195475, gi... - gi\|195587432\|ref\|XP_002083466.1\| GD13742 [Drosophila simulans], gi\|194195475\|gb\|EDX09051.1\| GD13742 ... gi\|194748795, gi... - gi\|194748795\|ref\|XP_001956828.1\| GF10123 [Drosophila ananassae], gi\|190624110\|gb\|EDV39634.1\| GF10123... gi\|194866032, gi... - gi\|194866032\|ref\|XP_001971723.1\| GG15115 [Drosophila erecta], gi\|190653506\|gb\|EDV50749.1\| GG15115 [D... gi\|195491363, gi... - gi\|38048569\|gb\|AAR10187.1\| similar to Drosophila melanogaster CG17737 [Drosophila yakuba], gi\|195491... gi\|195011583, gi... - gi\|195011583\|ref\|XP_001983218.1\| GH15775 [Drosophila grimshawi], gi\|193896700\|gb\|EDV95566.1\| GH15775... CG17737-PA - This gene is referred to in FlyBase by the symbol Dmel\CG17737 (CG17737, FBgn0035423). It is a prote... gi\|193918732, gi... - gi\|195125309\|ref\|XP_002007123.1\| GI12554 [Drosophila mojavensis], gi\|193918732\|gb\|EDW17599.1\| GI1255...	2.0E-33	[1..108]	[1..110]
gi\|157835180, gi... - gi\|5107727\|pdb\|2IF1\| Chain , Human Translation Initiation Factor Eif1, Nmr, 29 Structures, gi\|1578...	6.0E-33	[2..108]	[16..126]
gi\|226371892, gi... - gi\|226372304\|gb\|ACO51777.1\| Eukaryotic translation initiation factor 1b [Rana catesbeiana], gi\|22637... gi\|18656840, gi\|... - gi\|54311175\|gb\|AAH84740.1\| SUI1 protein [Xenopus laevis], gi\|32450007\|gb\|AAH54139.1\| Gc20-pending-pr... gi\|45360683, gi\|... - gi\|45360683\|ref\|NP_989015.1\| suppressor of initiator codon mutations, related sequence 1 [Xenopus (S...	3.0E-32	[2..108]	[3..113]
tr\|G3HLU5\|G3HLU5... - Eukaryotic translation initiation factor 1 OS=Cricetulus griseus GN=I79_011689 PE=4 SV=1 gi\|149054211, gi... - gi\|166797081\|gb\|AAI59407.1\| Eukaryotic translation initiation factor 1 [Rattus norvegicus], gi\|15778... EIF1_MOUSE - Eukaryotic translation initiation factor 1 OS=Mus musculus GN=Eif1 PE=1 SV=2	4.0E-32	[2..108]	[3..113]

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Predicted Domain #1

Region A:
Residues: [1-108]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSIENLKSFD PFADTGDDET ATSNYIHIRI QQRNGRKTLT TVQGVPEEYD LKRILKVLKK  60
   61 DFACNGNIVK DPEMGEIIQL QGDQRAKVCE FMISQLGLQK KNIKIHGF

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	323.69897
Match:	2if1__
Description:	Eukaryotic translation initiation factor eIF-1 (SUI1)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
translation initiation factor activity	6.56930940751046	bayes_pls_golite062009
nucleic acid binding	2.96971687610169	bayes_pls_golite062009
binding	2.42849959483419	bayes_pls_golite062009
translation regulator activity	2.27579767245564	bayes_pls_golite062009
translation factor activity, nucleic acid binding	2.25914933413253	bayes_pls_golite062009
protein binding	0.420735403363425	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: