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View Structure Prediction Details

Protein: CNM67
Organism: Saccharomyces cerevisiae
Length: 581 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CNM67.

Description E-value Query
Range
Subject
Range
MYH4_PIG - Myosin-4 OS=Sus scrofa GN=MYH4 PE=2 SV=1
6.0E-69 [6..576] [798..1378]
gi|14250231, gi|... - ref|NP_659210.1| myosin, heavy polypeptide 2, skeletal muscle, adult [Mus musculus], gi|14250231|gb...
1.0E-67 [6..576] [803..1383]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
2.0E-67 [6..576] [12..592]
MYH2_BOVIN - Myosin-2 OS=Bos taurus GN=MYH2 PE=2 SV=1
2.0E-67 [6..576] [801..1381]
gi|12053672 - gi|12053672|emb|CAC20413.1| beta-myosin heavy chain [Homo sapiens]
3.0E-67 [6..576] [796..1376]

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Predicted Domain #1
Region A:
Residues: [1-357]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTDFDLMNFP FHERLDSPVS ENGEIKDGEP IPQNWLNENH VGKSILPLFV NPEDVINCNF  60
   61 SNARDSYEEN KSPSMDQMNY ARNTSYQESP GLQERPKNEK DKSPIGTDVH KKDVPNFIHS 120
  121 TPRENSSKHF TRANEQASAQ PTDEHTSPDI SIEDCNGAKI FLQNSLSKED FRMLENVILG 180
  181 YQKKVIELGR DNLRQEERAN SLQKELEAAT KSNDKTLDNK KKIEEQTVLI ENLTKDLSLN 240
  241 KEMLEKANDT IQTKHTALLS LTDSLRKAEL FEIPIGILFF DLYDSEENSS KLDHILQEKY 300
  301 PNIKGFLCAS QQEELSRISQ RFKNAKAEAE DLRNELENKK IEIQTMREKN NTLIGTN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 30.30103
Match: 1i84S_
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [358-464]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KTLSKQNKIL CDKFDKLTID EKEILKGCNE EIKIKLERLN ERLGSWEKSK EKYETSLKDK  60
   61 EKMLADAEKK TNTLSKELDN LRSRFGNLEG NTSERITIKN ILQSRPD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 12.045757
Match: 1c1gA_
Description: Tropomyosin
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [465-581]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ISAEECNFLM VEQIDSANLT TLQNTVKEIV LAVGIPYPKL RRKIPLLAIK LKYENIMLSN  60
   61 FAQRLHRQVY SQEMNLKKFT DQAYYDFMST RRMDSIDHHL ERCLDHLYDH ILEKMVK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.534 0.118 microtubule nucleation a.74.1 Cyclin-like
View Download 0.396 0.114 microtubule nucleation a.21.1 HMG-box
View Download 0.381 0.076 microtubule nucleation a.73.1 Retrovirus capsid protein, N-terminal core domain
View Download 0.374 N/A N/A a.73.1 Retrovirus capsid protein, N-terminal core domain
View Download 0.361 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.359 N/A N/A a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.336 N/A N/A a.74.1 Cyclin-like
View Download 0.319 N/A N/A a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.312 N/A N/A d.56.1 GroEL-intermediate domain like
View Download 0.290 N/A N/A a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.276 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.274 N/A N/A a.60.9 lambda integrase-like, N-terminal domain
View Download 0.274 N/A N/A d.58.44 Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
View Download 0.265 N/A N/A a.24.17 Group V grass pollen allergen
View Download 0.258 N/A N/A c.51.2 TolB, N-terminal domain
View Download 0.257 N/A N/A a.70.1 N-terminal domain of the delta subunit of the F1F0-ATP synthase
View Download 0.246 N/A N/A a.40.1 Calponin-homology domain, CH-domain
View Download 0.245 N/A N/A a.133.1 Phospholipase A2, PLA2
View Download 0.243 N/A N/A a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.236 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.234 N/A N/A d.236.1 DNA-binding protein Tfx
View Download 0.233 N/A N/A a.61.1 Retroviral matrix proteins
View Download 0.230 N/A N/A a.69.3 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain
View Download 0.227 N/A N/A a.91.1 Regulator of G-protein signalling, RGS
View Download 0.226 N/A N/A a.39.1 EF-hand
View Download 0.225 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.220 N/A N/A a.91.1 Regulator of G-protein signalling, RGS
View Download 0.213 N/A N/A c.51.1 Anticodon-binding domain of Class II aaRS
View Download 0.202 N/A N/A d.15.1 Ubiquitin-like
View Download 0.201 N/A N/A a.64.1 Saposin


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle