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View Structure Prediction Details

Protein: CHS1
Organism: Saccharomyces cerevisiae
Length: 1131 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CHS1.

Description E-value Query
Range
Subject
Range
CHS1 - Chitin synthase I, requires activation from zymogenic form in order to catalyze the transfer of N-ac...
0.0 [1..1131] [1..1131]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [203..1126] [9..916]
gi|83774827, gi|... - gi|83774827|dbj|BAE64950.1| unnamed protein product [Aspergillus oryzae], gi|19071965|dbj|BAB85684.1...
gi|169783242 - gi|169783242|ref|XP_001826083.1| hypothetical protein [Aspergillus oryzae RIB40]
0.0 [191..1128] [13..920]
gi|9082308 - gi|9082308|gb|AAF82801.1|AF276826_1 class I chitin synthase [Coccidioides posadasii]
0.0 [163..1126] [17..912]
CHS3_NEUCR - Chitin synthase 3 OS=Neurospora crassa GN=chs-3 PE=3 SV=2
CHS3_NEUCR - Chitin synthase 3 OS=Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGS...
0.0 [217..1128] [2..888]
CHS2_EXODE - Chitin synthase 2 OS=Exophiala dermatitidis GN=CHS2 PE=3 SV=2
0.0 [172..1126] [3..919]
gi|6176510 - gi|6176510|gb|AAF05595.1|AF188934_1 chitin synthase [Blumeria graminis]
0.0 [361..1128] [2..760]
gi|19068022 - gi|19068022|gb|AAL23717.1| chitin synthase A [Glomerella graminicola]
0.0 [188..1128] [2..899]
CHSA_AMPQU - Chitin synthase A OS=Ampelomyces quisqualis GN=CHSA PE=3 SV=1
0.0 [228..1126] [2..900]

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Predicted Domain #1
Region A:
Residues: [1-142]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDQNNRSRN EYHSNRKNEP SYELQNAHSG LFHSSNEELT NRNQRYTNQN ASMGSFTPVQ  60
   61 SLQFPEQSQQ TNMLYNGDDG NNNTINDNER DIYGGFVNHH RQRPPPATAE YNDVFNTNSQ 120
  121 QLPSEHQYNN VPSYPLPSIN VI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 2.69897
Match: 1deqA_
Description: Fibrinogen
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [143-409]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QTTPELIHNG SQTMATPIER PFFNENDYYY NNRNSRTSPS IASSSDGYAD QEARPILEQP  60
   61 NNNMNSGNIP QYHDQPFGYN NGYHGLQAKD YYDDPEGGYI DQRGDDYQIN SYLGRNGEMV 120
  121 DPYDYENSLR HMTPMERREY LHDDSRPVND GKEELDSVKS GYSHRDLGEY DKDDFSRDDE 180
  181 YDDLNTIDKL QFQANGVPAS SSVSSIGSKE SDIIVSNDNL TANRALKRSG TEIRKFKLWN 240
  241 GNFVFDSPIS KTLLDQYATT TENANTL

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 14.32
Match: 1k83A
Description: RBP1
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [410-488]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PNEFKFMRYQ AVTCEPNQLA EKNFTVRQLK YLTPRETELM LVVTMYNEDH ILLGRTLKGI  60
   61 MDNVKYMVKK KNSSTWGPD

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.451 d.26.1 FKBP-like
View Download 0.579 d.80.1 Tautomerase/MIF
View Download 0.633 d.68.1 Translation initiation factor IF3, C-terminal domain
View Download 0.350 c.13.2 Anti-sigma factor antagonist SpoIIaa
View Download 0.360 c.102.1 Cell-division inhibitor MinC, N-terminal domain
View Download 0.304 d.56.1 GroEL-intermediate domain like
View Download 0.300 c.110.1 D-Tyr tRNAtyr deacylase, DTD
View Download 0.298 d.51.1 Eukaryotic type KH-domain (KH-domain type I)
View Download 0.296 c.25.1 Ferredoxin reductase-like, C-terminal NADP-linked domain
View Download 0.291 d.58.19 Bacterial exopeptidase dimerisation domain
View Download 0.281 d.6.1 Prion-like
View Download 0.249 d.14.1 Ribosomal protein S5 domain 2-like
View Download 0.246 d.58.13 Anticodon-binding domain of PheRS
View Download 0.244 a.4.9 Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3
View Download 0.236 c.58.1 Aminoacid dehydrogenase-like, N-terminal domain
View Download 0.235 c.26.2 Adenine nucleotide alpha hydrolases-like
View Download 0.235 a.46.1 Methionine synthase domain
View Download 0.226 c.2.1 NAD(P)-binding Rossmann-fold domains
View Download 0.222 a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.220 d.68.4 YhbY-like
View Download 0.219 d.15.11 Doublecortin (DC)
View Download 0.204 c.1.8 (Trans)glycosidases
View Download 0.204 a.29.4 RecG, N-terminal domain
View Download 0.204 a.24.7 FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)
View Download 0.202 d.56.1 GroEL-intermediate domain like
View Download 0.202 d.109.1 Actin depolymerizing proteins
View Download 0.200 c.37.1 P-loop containing nucleoside triphosphate hydrolases

Predicted Domain #4
Region A:
Residues: [489-565]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AWKKIVVCII SDGRSKINER SLALLSSLGC YQDGFAKDEI NEKKVAMHVY EHTTMINITN  60
   61 ISESEVSLEC NQGTVPI

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [696-855]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YGEIMENEGF HFFSSNMYLA EDRILCFEVV TKKNCNWILK YCRSSYASTD VPERVPEFIL  60
   61 QRRRWLNGSF FASVYSFCHF YRVWSSGHNI GRKLLLTVEF FYLFFNTLIS WFSLSSFFLF 120
  121 FRILTVSIAL AYHSAFNVLS VIFLWLYGIC TLSTFILSLG 

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 7.7
Match: 1dioA
Description: Diol dehydratase, alpha subunit
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [566-695]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QLLFCLKEQN QKKINSHRWA FEGFAELLRP NIVTLLDAGT MPGKDSIYQL WREFRNPNVG  60
   61 GACGEIRTDL GKRFVKLLNP LVASQNFEYK MSNILDKTTE SNFGFITVLP GAFSAYRFEA 120
  121 VRGQPLQKYF 

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 7.7
Match: 1dioA
Description: Diol dehydratase, alpha subunit
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transferase activity, transferring hexosyl groups 2.23446625487311 bayes_pls_golite062009
UDP-glycosyltransferase activity 1.84596125277114 bayes_pls_golite062009
catalytic activity 1.73979371332125 bayes_pls_golite062009
transferase activity 1.18156663897445 bayes_pls_golite062009
acetylgalactosaminyltransferase activity 0.823843077041128 bayes_pls_golite062009
cytidylyltransferase activity 0.666765511953956 bayes_pls_golite062009
nucleotidyltransferase activity 0.641710647713692 bayes_pls_golite062009
binding 0.61043334112269 bayes_pls_golite062009
polypeptide N-acetylgalactosaminyltransferase activity 0.600389101620522 bayes_pls_golite062009
transferase activity, transferring glycosyl groups 0.539883035270389 bayes_pls_golite062009
glucuronosyltransferase activity 0.510390802401046 bayes_pls_golite062009
mannosyltransferase activity 0.505948108814334 bayes_pls_golite062009
glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity 0.360354014290234 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.301396160525425 bayes_pls_golite062009
UDP-N-acetylglucosamine diphosphorylase activity 0.0309517682490415 bayes_pls_golite062009

Predicted Domain #6
Region A:
Residues: [856-908]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NKPKSTEKFY VLTCVIFAVM MIYMIFCSIF MSVKSFQNIL KNDTISFEGL ITT

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.408 a.4.5 "Winged helix" DNA-binding domain
View Download 0.417 a.4.1 Homeodomain-like
View Download 0.475 a.2.10 Epsilon subunit of F1F0-ATP synthase C-terminal domain
View Download 0.432 g.2.2 Neurotoxin B-IV
View Download 0.370 a.2.9 C-terminal UvrC-binding domain of UvrB
View Download 0.368 a.4.1 Homeodomain-like
View Download 0.362 a.157.1 Skp1 dimerisation domain-like
View Download 0.356 a.108.1 Ribosomal protein L7/12, oligomerisation (N-terminal) domain
View Download 0.352 a.144.2 Ribosomal protein L20
View Download 0.351 a.4.5 "Winged helix" DNA-binding domain
View Download 0.346 a.16.1 S15/NS1 RNA-binding domain
View Download 0.338 a.2.10 Epsilon subunit of F1F0-ATP synthase C-terminal domain
View Download 0.331 a.5.1 DNA helicase RuvA subunit, C-terminal domain
View Download 0.324 f.13.1 Family A G protein-coupled receptor-like
View Download 0.317 a.32.1 Transcription factor IIA (TFIIA), alpha-helical domain
View Download 0.315 a.30.1 ROP protein
View Download 0.301 a.32.1 Transcription factor IIA (TFIIA), alpha-helical domain
View Download 0.275 a.2.7 tRNA-binding arm
View Download 0.271 g.2.1 Heat-stable enterotoxin B
View Download 0.265 a.8.1 Bacterial immunoglobulin/albumin-binding domains
View Download 0.257 a.2.2 Ribosomal protein L29 (L29p)
View Download 0.255 a.4.5 "Winged helix" DNA-binding domain
View Download 0.247 a.46.2 Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain
View Download 0.213 a.112.1 Description not found.
View Download 0.212 g.34.1 HIV-1 VPU cytoplasmic domain
View Download 0.208 a.46.2 Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain
View Download 0.206 a.5.6 Hypothetical protein MTH1615
View Download 0.205 a.64.1 Saposin

Predicted Domain #7
Region A:
Residues: [909-1131]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EAFRDIVISL GSTYCLYLIS SIIYLQPWHM LTSFIQYILL SPSYINVLNI YAFCNVHDLS  60
   61 WGTKGAMANP LGKINTTEDG TFKMEVLVSS SEIQANYDKY LKVLNDFDPK SESRPTEPSY 120
  121 DEKKTGYYAN VRSLVIIFWV ITNFIIVAVV LETGGIADYI AMKSISTDDT LETAKKAEIP 180
  181 LMTSKASIYF NVILWLVALS ALIRFIGCSI YMIVRFFKKV TFR

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle