YRC Public Data Repository - Protein Structure Prediction

Protein:	MDG1
Organism:	Saccharomyces cerevisiae
Length:	366 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MDG1.

Description	E-value	Query Range	Subject Range
MDG1_YEAST - Signal transduction protein MDG1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MDG1 PE... MDG1 - Plasma membrane protein involved in G-protein mediated pheromone signaling pathway; overproduction s... MDG1_YEAS8 - Signal transduction protein MDG1 OS=Saccharomyces cerevisiae (strain Lalvin EC1118 / Prise de mousse...	0.0	[1..366]	[1..366]
gi\|5702015 - gi\|5702015\|emb\|CAB52141.1\| GAL83 protein [Solanum tuberosum]	3.0E-44	[11..155]	[109..250]
gi\|4099129, gi\|4... - gi\|4099424\|gb\|AAD00625.1\| AMP-activated protein kinase beta subunit [Homo sapiens], gi\|4099129\|gb\|AA...	3.0E-44	[10..154]	[82..234]
AAKB1_MOUSE - 5'-AMP-activated protein kinase subunit beta-1 OS=Mus musculus GN=Prkab1 PE=1 SV=2	3.0E-42	[10..154]	[82..234]
AAKB1_RAT - 5'-AMP-activated protein kinase subunit beta-1 OS=Rattus norvegicus GN=Prkab1 PE=1 SV=4	4.0E-42	[10..154]	[82..234]

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Predicted Domain #1

Region A:
Residues: [1-366]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQSSLPQFTF KWPKGPEAII LTGTFDDWKG TLPMVKDPSG AFEITLPVTF DSPSSKFYFK  60
   61 FIVDGQWLPS KDYKVNIDEG VENNFITEED VIKQRENGSS TLVPESAGLA VSKNAPLIEP 120
  121 EAEKRAKKLR KFKIKRVIKT NKQTGERSIF SQEVVELPDS EDETQQVNKT GKNADGLSGT 180
  181 TTIIENNVGV NEEKAIKPYE ENHPKVNLVK SEGYVTDGLG KTQSSESRLY ELSAEDLEKE 240
  241 EEEEDEDKGG GKDTSTSADA EASEDQNKEP LSKSAKFEKP EEKVPVSSIT SHAKETSVKP 300
  301 TGKVATETQT YETKQGAPTA AAKKIEAKKA TRPSKPKGTK ETPNKGVQKN PAKNGGFFKK 360
  361 LAQLLK

[Run NCBI BLAST on this sequence.]

Detection Method:	ORFEUS
Confidence:	13.44
Match:	1m2vB
Description:	Sec24
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits