YRC Public Data Repository - Protein Structure Prediction

Protein:	YNL108C
Organism:	Saccharomyces cerevisiae
Length:	270 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YNL108C.

Description	E-value	Query Range	Subject Range
gi\|190409096 - gi\|190409096\|gb\|EDV12361.1\| hypothetical protein SCRG_03243 [Saccharomyces cerevisiae RM11-1a] YNK8_YEAST - Uncharacterized protein YNL108C OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YNL108C ... YNL108C - Putative protein of unknown function with similarity to Tfc7p and prokaryotic phosphotransfer enzyme... gi\|151944427 - gi\|151944427\|gb\|EDN62705.1\| conserved protein [Saccharomyces cerevisiae YJM789]	1.0E-60	[1..270]	[1..270]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	4.0E-51	[1..226]	[1..240]
gi\|109090155, gi... - gi\|109149555\|ref\|XP_001082818.1\| PREDICTED: phosphoglycerate mutase 1 (brain) isoform 2 [Macaca mula... gi\|67970637 - gi\|67970637\|dbj\|BAE01661.1\| unnamed protein product [Macaca fascicularis] gi\|194041793 - gi\|194041793\|ref\|XP_001928786.1\| PREDICTED: similar to Phosphoglycerate mutase 1 (Phosphoglycerate m... gi\|114632193 - gi\|114632193\|ref\|XP_507959.2\| PREDICTED: phosphoglycerate mutase 1 (brain) isoform 3 [Pan troglodyte... PGAM1 - phosphoglycerate mutase 1 (brain) ENSCJAT00000032245 - null gi\|123992778, gi... - gi\|123999524\|gb\|ABM87317.1\| phosphoglycerate mutase 1 (brain) [synthetic construct], gi\|123992778\|gb...	5.0E-51	[1..226]	[1..240]
gi\|8248819 - gi\|8248819\|gb\|AAB19888.2\| phosphoglycerate mutase type B subunit [Rattus sp.]	8.0E-51	[1..226]	[1..240]
gi\|12844989 - gi\|12844989\|dbj\|BAB26576.1\| unnamed protein product [Mus musculus]	2.0E-50	[1..226]	[1..240]
PGAM2_RAT - Phosphoglycerate mutase 2 OS=Rattus norvegicus GN=Pgam2 PE=1 SV=2	3.0E-49	[1..226]	[1..240]

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Predicted Domain #1

Region A:
Residues: [1-270]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAIENIYIAR HGYRSNWLPK GPYPPPPTGI DNDVPLSEHG VEQAHELANY ISKLDVKPEM  60
   61 IFSSPFYRCL ETSKPTVEAL KIPLYVDRGV GEWYKPDRPI IPEPATHEVM SKFFPSMISP 120
  121 DWEPSIIPSN KGETEEDIFE RCHKFWPVFI DRVERKFPNV KTIMIVTHAA TKSALGMNLL 180
  181 KFSSAKEPID NKGTFIRNGS CAIDKFELVK GENESIPFEE REWKLTMNGN TSFLTNGEEM 240
  241 NWTFMNAFEA GSDADIKARR AAESGKLKME

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	77.980454
Match:	1bif__
Description:	6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, kinase domain; 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits