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View Structure Prediction Details

Protein: INP52
Organism: Saccharomyces cerevisiae
Length: 1183 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for INP52.

Description E-value Query
Range
Subject
Range
gi|929847 - gi|929847|emb|CAA90520.1| ORF N2160 [Saccharomyces cerevisiae]
1165.0 [0..1] [1101..1]
SYNJ2_MOUSE - Synaptojanin-2 OS=Mus musculus GN=Synj2 PE=1 SV=2
1034.0 [0..30] [1171..32]
gi|16647984 - gi|16647984|gb|AAK61722.1| synaptojanin 2B1 [Rattus norvegicus]
1025.0 [0..30] [1171..32]
gi|2702321 - gi|2702321|gb|AAC51921.1| synaptojanin [Homo sapiens]
1004.0 [0..15] [1178..21]

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Predicted Domain #1
Region A:
Residues: [1-475]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKILLSKQQT RKIAIVSETH GLVFRPINSK NSRRSTCAVE LVPKAELNGN GFRRLSNHEI  60
   61 YGFIGLIEIE GLMFIATITG KSKVAQPIPN KTVNKIYAVD FFCLNNSKWD FMDIDSSGYP 120
  121 IVTNDGDFAI SSPPSISTHS SRSSLRSSSS RSLNAQEQAP KHPCHELRKL LSNGSFYYST 180
  181 DFDLTCTLQK RGFTEHSLSF DDFDREFMWN SFLMDEIITY RDRLDVTAKE LLDQRGFLTT 240
  241 VIRGFAETIF SYINRLKVGL TIISRQSWKR AGTRFNARGI DDDGHVANFV ETEMIMYSSQ 300
  301 YCYAFTQIRG SLPIFWEQDT SLISPKIQIT RSVEATQPTF DEHFIRLFKK YGPVHIINLL 360
  361 STKSSEIQLS RRYKEQLKNS EKMKIGRDVF LTSFDFHRET SQDGFAAASR IIPKIRNTIL 420
  421 DAGYFSYDVK EGRLISEQDG VFRTNCLDCL DRTNLIQQTI SLAVFKLFLE DFRLV

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 183.337242
Match: PF02383
Description: SacI homology domain

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [476-559]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KPSSFIDDNE FVQKVNALWA DNGDQISQIY TGTNALKSSY SRKGKMSFSG ALSDATKSVS  60
   61 RMYINNFVDK GKQQNIDTLL GKLP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.833 a.8.11 Description not found.
View Download 0.813 a.7.6 Ribosomal protein S20
View Download 0.791 a.7.6 Ribosomal protein S20
View Download 0.763 a.7.6 Ribosomal protein S20
View Download 0.729 d.51.1 Eukaryotic type KH-domain (KH-domain type I)
View Download 0.722 a.29.10 Description not found.
View Download 0.671 a.133.1 Phospholipase A2, PLA2
View Download 0.668 f.17.1 F1F0 ATP synthase subunit C
View Download 0.668 f.17.1 F1F0 ATP synthase subunit C
View Download 0.663 a.7.6 Ribosomal protein S20

Predicted Domain #3
Region A:
Residues: [560-938]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HQQVVELYDP ICEYVNERLL ESEEKFTTHS NINLFVGTFN VNGNSRRADL SKWLFPIGDK  60
   61 FKPDVVVLGL QEVIELTAGS ILNADYTKSS FWETMVTDCL NQYEEKYLLL RVEQMSSLLI 120
  121 LFFARSDRAY NIKEVGGSTK KTGFGGITGN KGAVAIRFDY GATSFCFVNT HLSAGASNID 180
  181 ERRNDYNNIY RNITFPRSKT IPHHDSLFWL GDLNYRITLT NDEVRRELRA QKDGYIDRLL 240
  241 QYDQLTQEIN EGVVFQGFKE PTLQFRPTYK YDYGTDNYDT SEKARTPSWT DRIIYKGENL 300
  301 HPLAYSDAPL KISDHKPVYA AYRANVKFVD EKEKLNLVEK LYAEYKNTHP EALTTGPDEL 360
  361 SHARMEKQKE SIPLDATVQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 904.9897
Match: 1i9yA
Description: Synaptojanin, IPP5C domain
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [939-1183]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SAGIKLIDLD DTSSCVSPLL SGPSPQPSVV GPGGLSNVSP DKSKLNVLPP PPPTSRHNKE  60
   61 PSSKLLSPTK EISIVSVSPR KGESNLPALE RHSTPKPLPP VPALSLSKPV SLQKSSSELQ 120
  121 HAKETIDNGK IVPRPCPPIR RKSSTAPDEI STSTKNSGVS TTEDPEPAKA STKPEKPPVV 180
  181 KKPHYLSVAA NKLNTSQEHS IKVSPSNSKS EEELPCKKKS KPKVPAKNPE LEKLSVHPLK 240
  241 PCDPN

[Run NCBI BLAST on this sequence.]

Detection Method: ab initio
Confidence: 11.26
Match:
Description: No description for 1deqA was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle