YRC Public Data Repository - Protein Structure Prediction

Protein:	MSG5
Organism:	Saccharomyces cerevisiae
Length:	489 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MSG5.

Description	E-value	Query Range	Subject Range
gi\|459243 - gi\|459243\|dbj\|BAA04485.1\| protein-tyrosine phosphatase [Saccharomyces cerevisiae]	0.0	[1..489]	[1..489]
gi\|24586675, gi\|... - gi\|24586675\|ref\|NP_060327.2\| slingshot homolog 3 [Homo sapiens], gi\|18677034\|dbj\|BAB85080.1\| unnamed...	3.0E-68	[92..484]	[185..575]
gi\|9309340 - gi\|9309340\|dbj\|BAB03234.1\| protein-tyrosine phosphatase [Candida tropicalis]	9.0E-63	[12..376]	[158..573]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	3.0E-58	[12..376]	[155..580]
PTPX_CANAL - Probable tyrosine-protein phosphatase OS=Candida albicans GN=CPP1 PE=3 SV=1	2.0E-57	[12..376]	[155..580]
gi\|18485490, gi\|... - gi\|18485490\|ref\|NP_569714.1\| dual specificity phosphatase 16 isoform 1 [Mus musculus], gi\|13625393\|g...	2.0E-54	[194..473]	[123..409]

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Predicted Domain #1

Region A:
Residues: [1-216]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQFHSDKQHL DSKTDIDFKP NSPRSLQNRN TKNLSLDIAA LHPLMEFSSP SQDVPGSVKF  60
   61 PSPTPLNLFM KPKPIVLEKC PPKVSPRPTP PSLSMRRSEA SIYTLPTSLK NRTVSPSVYT 120
  121 KSSTVSSISK LSSSSPLSSF SEKPHLNRVH SLSVKTKDLK LKGIRGRSQT ISGLETSTPI 180
  181 SSTREGTLDS TDVNRFSNQK NMQTTLIFPE EDSDLN

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [217-403]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IDMVHAEIYQ RTVYLDGPLL VLPPNLYLYS EPKLEDILSF DLVINVAKEI PNLEFLIPPE  60
   61 MAHKIKYYHI EWTHTSKIVK DLSRLTRIIH TAHSQGKKIL VHCQCGVSRS ASLIVAYIMR 120
  121 YYGLSLNDAY NKLKGVAKDI SPNMGLIFQL MEWGTMLSKN SPGEEGETVH MPEEDDIGNN 180
  181 EVSSTTK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	122.502279
Match:	1mkp__
Description:	Mapk phosphatase
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [404-489]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SYSSASFRSF PMVTNLSSSP NDSSVNSSEV TPRTPATLTG ARTALATERG EDDEHCKSLS  60
   61 QPADSLEASV DNESISTAPE QMMFLP

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.851	0.035	protein amino acid dephosphorylation	a.24.13	Domain of the SRP/SRP receptor G-proteins

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits