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View Structure Prediction Details

Protein: LAP2
Organism: Saccharomyces cerevisiae
Length: 671 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for LAP2.

Description E-value Query
Range
Subject
Range
ANPEP - alanyl (membrane) aminopeptidase
0.0 [17..665] [24..730]
AMPN_RABIT - Aminopeptidase N OS=Oryctolagus cuniculus GN=ANPEP PE=1 SV=4
0.0 [16..667] [23..731]
AMPN_RAT - Aminopeptidase N OS=Rattus norvegicus GN=Anpep PE=1 SV=2
0.0 [17..665] [24..729]
gi|627700 - pir||A53984 membrane alanyl aminopeptidase (EC 3.4.11.2) - pig
AMPN_PIG - Aminopeptidase N OS=Sus scrofa GN=ANPEP PE=1 SV=3
0.0 [17..667] [24..729]
gi|4100305 - gi|4100305|gb|AAD09272.1| aminopeptidase N [Felis catus]
0.0 [5..667] [5..732]
gi|3452126 - gi|3452126|gb|AAC32754.1| aminopeptidase N [Pseudopleuronectes americanus]
0.0 [16..666] [23..738]
gi|26252164, gi|... - gi|26252164|gb|AAH40792.1| Anpep protein [Mus musculus], gi|16877511|gb|AAH17011.1| Anpep protein [M...
0.0 [17..665] [24..737]

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Predicted Domain #1
Region A:
Residues: [1-253]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFLLPFVIRH SSSIYLPTLR FRGLLTVISR NIHISTPHKM LPLSIEQRRP SRSPEYDQST  60
   61 LSNYKDFAVL HTDLNLSVSF EKSAISGSVT FQLKKLHEGK NKSDELHLDT SYLDVQEVHI 120
  121 DGSKADFQIE QRKEPLGSRL VINNASCNDN FTLNIQFRTT DKCTALQWLN SKQTKGGKPY 180
  181 VFSQLEAIHA RSLFPCFDTP SVKSTFTASI ESPLPVVFSG IRIEDTSKDT NIYRFEQKVP 240
  241 IPAYLIGIAS GDL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1330.0
Match: 1hs6A_
Description: Leukotriene A4 hydrolase C-terminal domain; Leukotriene A4 hydrolase N-terminal domain; Leukotriene A4 hydrolase catalytic domain
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [254-338]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSAPIGPRST VYTEPFRLKD CQWEFENDVE KFIQTAEKII FEYEWGTYDI LVNVDSYPYG  60
   61 GMESPNMTFA TPTLIAHDRS NIDVI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1330.0
Match: 1hs6A_
Description: Leukotriene A4 hydrolase C-terminal domain; Leukotriene A4 hydrolase N-terminal domain; Leukotriene A4 hydrolase catalytic domain
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [339-508]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AHELAHSWSG NLVTNCSWNH FWLNEGWTVY LERRIIGAIH GEPTRHFSAL IGWSDLQNSI  60
   61 DSMKDPERFS TLVQNLNDNT DPDDAFSTVP YEKGFNLLFH LETILGGKAE FDPFIRHYFK 120
  121 KFAKKSLDTF QFLDTLYEFY PEKKEILDSV DWETWLYKPG MPPRPHFITA 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1330.0
Match: 1hs6A_
Description: Leukotriene A4 hydrolase C-terminal domain; Leukotriene A4 hydrolase N-terminal domain; Leukotriene A4 hydrolase catalytic domain
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [509-671]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LADNVYQLAD KWVEMAQHLK TTEDFRSEFN AIDIKDFNSN QLVLFLETLT QNGHSNKKPK  60
   61 DFDWAKFPVA SRALLDIYQD NIVKSQNAEV VFKMFKFQIF AKLQEEYKHL ADWLGTVGRM 120
  121 KFVRPGYRLL NSVDRRLALA TFDKFKDTYH PICKALVKQD LGL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1330.0
Match: 1hs6A_
Description: Leukotriene A4 hydrolase C-terminal domain; Leukotriene A4 hydrolase N-terminal domain; Leukotriene A4 hydrolase catalytic domain
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle