YRC Public Data Repository - Protein Structure Prediction

Protein:	SPO1
Organism:	Saccharomyces cerevisiae
Length:	631 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPO1.

Description	E-value	Query Range	Subject Range
SPO1 - Meiosis-specific prospore protein; required for meiotic spindle pole body duplication and separation... SPO1_YEAST - Putative meiotic phospholipase SPO1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SPO1...	0.0	[1..631]	[1..631]
gi\|20258069 - gi\|20258069\|gb\|AAM16160.1\| phospholipase B [Candida glabrata]	0.0	[3..630]	[11..585]
PLB_KLULA - Lysophospholipase OS=Kluyveromyces lactis GN=PLB PE=1 SV=1 PLB_KLULA - Lysophospholipase OS=Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRR...	0.0	[3..631]	[17..585]
gi\|32420267, gi\|... - gi\|32420267\|ref\|XP_330577.1\| hypothetical protein ( (AF045574) lysophospholipase [Neurospora crassa]... gi\|85111965 - gi\|85111965\|ref\|XP_964190.1\| hypothetical protein ( (AF045574) lysophospholipase [Neurospora crassa ...	0.0	[13..631]	[34..590]
PLB1_ASPFC - Lysophospholipase 1 OS=Neosartorya fumigata (strain CEA10 / CBS 144.89 / FGSC A1163) GN=plb1 PE=1 SV... PLB1_ASPFU - Lysophospholipase 1 OS=Aspergillus fumigatus GN=plb1 PE=2 SV=1 PLB1_ASPFU - Lysophospholipase 1 OS=Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)...	0.0	[16..630]	[39..589]
PLB1_TORDE - Lysophospholipase OS=Torulaspora delbrueckii PE=1 SV=1	0.0	[11..631]	[21..580]

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Predicted Domain #1

Region A:
Residues: [1-631]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQKLLFVFSV LLTVVLATAP FQVQCPSSPL IREAKHELCP EETLYLKKKK IKTKNKLIQF  60
   61 LKSLTEAKFS SKFYKRVLKD PPKIGIAISG GGYRSMLVGT GFISQMNDYG LFEYSDYIAG 120
  121 LSGGSWILMD LVVQNFEVKS LLQEWDLEED LLLGIPEFDI SEEEIVTNAK KEYNDNDLKM 180
  181 KKRQGGSLIT SSSNFYEQIE EIMNSIEEIP EDYMITKRNL NPLARLKKIF FPNNTFTGTD 240
  241 AKIETFKKVL DFYKSLHLKI KPKKMEGFQI SFTDYWGKAI VQRLKKNFDD DPNHSFSFSK 300
  301 LVNSSKKFKE CSVPIPIFVA NCKNGLLSNV IFEFTPFEFG SWENILRLFV KLPYLGSKIV 360
  361 SGKAEKCINN FDDLGFITAT SSSIFNNVLI FIWNLASQSS REAMKALNMV MGIFGLGKEE 420
  421 IFSISKDSSR LETDYAVYQP NPFYLYPEKD NVLTNKNHLY LVDGGEDGEN IPLRTLVIPE 480
  481 RELDVIFVLD SSSDIDNYPN GSKLKRIFEK LDEENVHYQF PNNVKTFTHP IVIGCNATKR 540
  541 TGHDSFLPII IYHANANHGN ASNTSTFKIT YNQSEVSSML PTGRGVFSND YDLYYKNCLG 600
  601 CILTKRTMDR LPRKKKFSPF CLQCFKDYCY S

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	93.522879
Match:	1cjyA_
Description:	Domain from cytosolic phospholipase A2; Cytosolic phospholipase A2 catalytic domain
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [563-631]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NTSTFKITYN QSEVSSMLPT GRGVFSNDYD LYYKNCLGCI LTKRTMDRLP RKKKFSPFCL  60
   61 QCFKDYCYS

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	1.74
Match:	1cjyA
Description:	Domain from cytosolic phospholipase A2; Cytosolic phospholipase A2 catalytic domain
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits