YRC Public Data Repository - Protein Structure Prediction

Protein:	YMR315W
Organism:	Saccharomyces cerevisiae
Length:	349 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YMR315W.

Description	E-value	Query Range	Subject Range
YMR315W - Protein with NADP(H) oxidoreductase activity; transcription is regulated by Stb5p in response to NAD... YM94_YEAST - Uncharacterized protein YMR315W OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YMR315W ...	5.0E-70	[1..349]	[1..349]
gi\|25328435 - pir\|\|C84130 oxidoreductase BH3843 [imported] - Bacillus halodurans (strain C-125) gi\|15616405, gi\|... - gi\|15616405\|ref\|NP_244710.1\| oxidoreductase [Bacillus halodurans C-125], gi\|10176468\|dbj\|BAB07562.1\|...	9.0E-67	[4..345]	[5..334]
gi\|4981103, gi\|1... - gi\|4981103\|gb\|AAD35670.1\|AE001733_7 lipopolysaccharide biosynthesis protein BplA [Thermotoga maritim... gi\|7462872 - pir\|\|B72359 lipopolysaccharide biosynthesis protein BplA - Thermotoga maritima (strain MSB8)	4.0E-66	[3..347]	[2..346]
gi\|7429797 - pir\|\|D71201 hypothetical protein PH1881 - Pyrococcus horikoshii gi\|3258320, gi\|1... - gi\|3258320\|dbj\|BAA31003.1\| 371aa long hypothetical protein [Pyrococcus horikoshii OT3], gi\|14591627\|...	1.0E-65	[3..348]	[34..370]
gi\|14245984, gi\|... - gi\|15923207\|ref\|NP_370741.1\| NADH-dependent dehydrogenase [Staphylococcus aureus subsp. aureus Mu50]... gi\|156720682, gi... - gi\|156978547\|ref\|YP_001440806.1\| hypothetical protein SAHV_0216 [Staphylococcus aureus subsp. aureus...	1.0E-63	[1..340]	[1..353]
gi\|25506937 - pir\|\|E89784 hypothetical protein SA0210 [imported] - Staphylococcus aureus (strain N315) gi\|15925921, gi\|... - gi\|15925921\|ref\|NP_373454.1\| hypothetical protein SA0210 [Staphylococcus aureus subsp. aureus N315],... gi\|90582884, gi\|... - gi\|90582884\|ref\|ZP_01238646.1\| Oxidoreductase, N-terminal:Oxidoreductase, C-terminal [Staphylococcus... gi\|90584937, gi\|... - gi\|90584937\|ref\|ZP_01240649.1\| Oxidoreductase, N-terminal:Oxidoreductase, C-terminal [Staphylococcus...	2.0E-63	[1..340]	[1..353]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	9.0E-63	[2..349]	[9..348]
gi\|5459153, gi\|1... - gi\|5459153\|emb\|CAB50639.1\| NADH dependent dyhydrogenase related protein [Pyrococcus abyssi GE5], gi\|... gi\|5459153, gi\|7... - pir\|\|A75025 NADH-dependent dyhydrogenase related protein PAB1138 - Pyrococcus abyssi (strain Orsay),...	1.0E-62	[3..348]	[4..340]
SPAC26H5.09c - GFO /IDH /MocA family oxidoreductase YEG9_SCHPO - Uncharacterized oxidoreductase C26H5.09c OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=S...	1.0E-62	[1..339]	[1..361]

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Predicted Domain #1

Region A:
Residues: [1-127]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSPLNVGIVG TGIFARDRHL PSYQEFPDKF KVIAAFNRHK AKALDFAKVA DIPENKVYDN  60
   61 LDEILNDPHV DYIDALLPAQ FNADIVEKAV KAGKPVILEK PIAANLDQAK EIVKIAESTP 120
  121 LPVGVAE

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [296-322]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GVNAEFLNFH EAVSKKDKSL YLGTPRT

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	167.29073
Match:	1evjA_
Description:	Glucose-fructose oxidoreductase, N-terminal domain; Glucose-fructose oxidoreductase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	2.54843319568228	bayes_pls_golite062009
oxidoreductase activity	1.02788681172101	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [128-295]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NWLYLPCIKI AKEQIEKIGP VVAFTHNSTG PFVTQNKYLT TTWRQKPEHI GGFLSDGGVH  60
   61 QLALVISLLG EFGSVSALTR QVRERSGADD IVFATVQLKN KEVIGSFTYG SAFGATEKSV 120
  121 FLKVYGKNGT VTVDLSDKKD PVVKVKLGGS AEDNGDEQIF KVDNDESF

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [323-349]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AFHHLACVDA FLKSSAKNGD YVKIEQP

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	167.29073
Match:	1evjA_
Description:	Glucose-fructose oxidoreductase, N-terminal domain; Glucose-fructose oxidoreductase
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: