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View Structure Prediction Details

Protein: ADH2
Organism: Saccharomyces cerevisiae
Length: 348 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ADH2.

Description E-value Query
Range
Subject
Range
ADH2 - Glucose-repressible alcohol dehydrogenase II, catalyzes the conversion of ethanol to acetaldehyde; i...
ADH2_YEAST - Alcohol dehydrogenase 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ADH2 PE=1 SV=3
0.0 [1..348] [1..348]
gi|7248741 - gi|7248741|gb|AAF43645.1|AF218309_1 alcohol dehydrogenase isozyme 3; Adh3 [Saccharomyces kluyveri]
0.0 [2..348] [27..373]
ADH1_KLULA - Alcohol dehydrogenase 1 OS=Kluyveromyces lactis GN=ADH1 PE=3 SV=1
ADH1_KLULA - Alcohol dehydrogenase 1 OS=Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267...
0.0 [2..348] [4..350]
ADH1_KLUMA - Alcohol dehydrogenase 1 OS=Kluyveromyces marxianus GN=ADH1 PE=3 SV=1
0.0 [1..348] [1..348]

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Predicted Domain #1
Region A:
Residues: [1-153]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSIPETQKAI IFYESNGKLE HKDIPVPKPK PNELLINVKY SGVCHTDLHA WHGDWPLPTK  60
   61 LPLVGGHEGA GVVVGMGENV KGWKIGDYAG IKWLNGSCMA CEYCELGNES NCPHADLSGY 120
  121 THDGSFQEYA TADAVQAAHI PQGTDLAEVA PIL

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [315-348]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KSPIKVVGLS SLPEIYEKME KGQIAGRYVV DTSK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 284.156545
Match: 1e3jA_
Description: Ketose reductase (sorbitol dehydrogenase)
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [154-314]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 CAGITVYKAL KSANLRAGHW AAISGAAGGL GSLAVQYAKA MGYRVLGIDG GPGKEELFTS  60
   61 LGGEVFIDFT KEKDIVSAVV KATNGGAHGI INVSVSEAAI EASTRYCRAN GTVVLVGLPA 120
  121 GAKCSSDVFN HVVKSISIVG SYVGNRADTR EALDFFARGL V

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 284.156545
Match: 1e3jA_
Description: Ketose reductase (sorbitol dehydrogenase)
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle