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View Structure Prediction Details

Protein: RCE1
Organism: Saccharomyces cerevisiae
Length: 315 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RCE1.

Description E-value Query
Range
Subject
Range
RCE1 - Type II CAAX prenyl protease involved in the proteolysis and maturation of Ras and the a-factor mati...
gi|190408500 - gi|190408500|gb|EDV11765.1| protease [Saccharomyces cerevisiae RM11-1a]
RCE1_YEAST - CAAX prenyl protease 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RCE1 PE=1 SV=1
0.0 [1..315] [1..315]
SPAC1687.02 - CAAX prenyl protease
RCE1_SCHPO - Probable CAAX prenyl protease 2 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPAC1687.0...
1.0E-69 [7..296] [4..246]
RCE1 - RCE1 homolog, prenyl protein peptidase (S. cerevisiae)
2.0E-66 [11..257] [43..270]
FACE2_MOUSE - CAAX prenyl protease 2 OS=Mus musculus GN=Rce1 PE=2 SV=1
9.0E-65 [11..257] [43..270]
Sras-PA - The gene severas is referred to in FlyBase by the symbol Dmel\Sras (CG4852, FBgn0029121). It is a pr...
gi|220954262, gi... - gi|220954262|gb|ACL89674.1| Sras-PA [synthetic construct], gi|220944384|gb|ACL84735.1| Sras-PA [synt...
6.0E-61 [11..257] [35..254]

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Predicted Domain #1
Region A:
Residues: [1-89]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLQFSTFLVL LYISISYVLP LYATSQPEGS KRDNPRTIKS RMQKLTIMLI SNLFLVPFLQ  60
   61 SQLSSTTSHI SFKDAFLGLG IIPGYYAAL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [90-315]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PNPWQFSQFV KDLTKCVAML LTLYCGPVLD FVLYHLLNPK SSILEDFYHE FLNIWSFRNF  60
   61 IFAPITEEIF YTSMLLTTYL NLIPHSQLSY QQLFWQPSLF FGLAHAHHAY EQLQEGSMTT 120
  121 VSILLTTCFQ ILYTTLFGGL TKFVFVRTGG NLWCCIILHA LCNIMGFPGP SRLNLHFTVV 180
  181 DKKAGRISKL VSIWNKCYFA LLVLGLISLK DTLQTLVGTP GYRITL

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 30.958607
Match: PF02517
Description: CAAX amino terminal protease family

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term Confidence Notes
succinate dehydrogenase activity 1.20204086283202 bayes_pls_golite062009
binding 1.05108618626228 bayes_pls_golite062009
catalytic activity 0.916346296983561 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle