YRC Public Data Repository - Protein Structure Prediction

Protein:	TIF11
Organism:	Saccharomyces cerevisiae
Length:	153 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TIF11.

Description	E-value	Query Range	Subject Range
gi\|222092845, gi... - gi\|223633892\|ref\|NP_001138651.1\| eukaryotic translation initiation factor 1A, X-linked [Ovis aries],... gi\|81674702 - gi\|81674702\|gb\|AAI09651.1\| Eukaryotic translation initiation factor 1A, X-linked [Bos taurus] gi\|60654937, gi\|... - gi\|60654939\|gb\|AAX32034.1\| eukaryotic translation initiation factor 1A [synthetic construct], gi\|606... ENSCJAT00000010387 - null IF1AX_PONAB - Eukaryotic translation initiation factor 1A, X-chromosomal OS=Pongo abelii GN=EIF1AX PE=2 SV=3 IF1AX_PONPY - Eukaryotic translation initiation factor 1A, X-chromosomal - Pongo pygmaeus (Orangutan) gi\|49257578, gi\|... - gi\|49257578\|gb\|AAH74155.1\| MGC81905 protein [Xenopus laevis], gi\|46250212\|gb\|AAH68786.1\| MGC81333 pr... gi\|49257921, gi\|... - gi\|89269515\|emb\|CAJ82618.1\| eukaryotic translation initiaion factor 1a [Xenopus tropicalis], gi\|5234... IF1AX_MOUSE - Eukaryotic translation initiation factor 1A, X-chromosomal OS=Mus musculus GN=Eif1ax PE=2 SV=3 tr\|M3XFD6\|M3XFD6... - Eukaryotic translation initiation factor 1A, X-linked OS=Felis catus GN=EIF1AX PE=3 SV=1 gi\|109130143 - gi\|109130143\|ref\|XP_001086305.1\| PREDICTED: similar to eukaryotic translation initiation factor 1A, ... gi\|74007185 - gi\|74007185\|ref\|XP_854509.1\| PREDICTED: similar to eukaryotic translation initiation factor 1A, Y-li... EIF1AX - eukaryotic translation initiation factor 1A, X-linked gi\|27708964, gi\|... - gi\|27708964\|ref\|XP_217622.1\| PREDICTED: similar to eukaryotic translation initiation factor 1A, Y-li...	6.0E-43	[1..131]	[1..131]
tif11 - translation initiation factor eIF1A IF1A_SCHPO - Eukaryotic translation initiation factor 1A OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) G...	6.0E-43	[1..137]	[1..137]
tr\|G3HTM9\|G3HTM9... - Eukaryotic translation initiation factor 1A OS=Cricetulus griseus GN=I79_014257 PE=3 SV=1 IF1A_RAT - Eukaryotic translation initiation factor 1A OS=Rattus norvegicus GN=Eif1a PE=2 SV=3 IF1A_MOUSE - Eukaryotic translation initiation factor 1A OS=Mus musculus GN=Eif1a PE=2 SV=3	1.0E-42	[1..131]	[1..131]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	2.0E-42	[1..131]	[1..131]
IF1A_ONOVI - Eukaryotic translation initiation factor 1A OS=Onobrychis viciifolia PE=2 SV=2	4.0E-42	[1..149]	[1..143]
gi\|7546514 - gi\|7546514\|pdb\|1D7Q\|B Chain B, Human Translation Initiation Factor Eif1a	4.0E-42	[2..131]	[1..130]
gi\|55241489, gi\|... - gi\|58383799\|ref\|XP_312806.2\| AGAP003119-PA [Anopheles gambiae str. PEST], gi\|55241489\|gb\|EAA08471.2\|... gi\|5690414 - gi\|5690414\|gb\|AAD47075.1\|AF164151_1 translation initiation factor 4C (1A) [Anopheles gambiae]	8.0E-42	[1..144]	[1..143]
gi\|14190445, gi\|... - gi\|15450561\|gb\|AAK96458.1\| At2g04520/T1O3.7 [Arabidopsis thaliana], gi\|14190445\|gb\|AAK55703.1\|AF3789...	3.0E-41	[1..149]	[1..143]
IF1A_RABIT - Eukaryotic translation initiation factor 1A OS=Oryctolagus cuniculus GN=EIF1A PE=1 SV=2	3.0E-41	[1..131]	[1..131]

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Predicted Domain #1

Region A:
Residues: [1-153]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGKKNTKGGK KGRRGKNDSD GPKRELIYKE EGQEYAQITK MLGNGRVEAS CFDGNKRMAH  60
   61 IRGKLRKKVW MGQGDIILVS LRDFQDDQCD VVHKYNLDEA RTLKNQGELP ENAKINETDN 120
  121 FGFESDEDVN FEFGNADEDD EEGEDEELDI DDI

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	427.927757
Match:	1d7qA_
Description:	Translation initiation factor-1a, eIF1a
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	0.141433535514844	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: