| Protein: | ESC1 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 1658 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ESC1.
| Description | E-value | Query Range |
Subject Range |
|
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0.0 | [94..1172] | [848..1930] |
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0.0 | [94..1172] | [849..1931] |
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0.0 | [94..1182] | [849..1941] |
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0.0 | [94..1172] | [848..1930] |
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0.0 | [94..1172] | [849..1931] |
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|
0.0 | [94..1172] | [847..1929] |
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Region A: Residues: [1-72] |
1 11 21 31 41 51
| | | | | |
1 MSKKKETFTP RANKLKLTTP RRKLKILSSL LDADEDSKMK DQHGYSRVHN DKYRVAKPTQ 60
61 HSTLHESISS RR
|
| Detection Method: |  |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.551 | 0.977 | chromatin silencing at telomere | a.4.1 | Homeodomain-like |
| View | Download | 0.399 | 0.977 | chromatin silencing at telomere | a.56.1 | CO dehydrogenase ISP C-domain like |
| View | Download | 0.378 | 0.977 | chromatin silencing at telomere | a.144.1 | PABC (PABP) domain |
| View | Download | 0.304 | 0.977 | chromatin silencing at telomere | a.46.2 | Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain |
| View | Download | 0.385 | 0.977 | chromatin silencing at telomere | a.60.9 | lambda integrase-like, N-terminal domain |
| View | Download | 0.650 | 0.977 | chromatin silencing at telomere | a.56.1 | CO dehydrogenase ISP C-domain like |
| View | Download | 0.548 | 0.977 | chromatin silencing at telomere | a.159.2 | FF domain |
| View | Download | 0.425 | 0.977 | chromatin silencing at telomere | a.56.1 | CO dehydrogenase ISP C-domain like |
| View | Download | 0.378 | 0.977 | chromatin silencing at telomere | d.40.1 | CI-2 family of serine protease inhibitors |
| View | Download | 0.337 | 0.977 | chromatin silencing at telomere | a.4.6 | C-terminal effector domain of the bipartite response regulators |
| View | Download | 0.277 | 0.977 | chromatin silencing at telomere | a.35.1 | lambda repressor-like DNA-binding domains |
| View | Download | 0.275 | 0.977 | chromatin silencing at telomere | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.273 | 0.977 | chromatin silencing at telomere | c.78.2 | Aspartate/glutamate racemase |
| View | Download | 0.269 | 0.977 | chromatin silencing at telomere | a.4.1 | Homeodomain-like |
| View | Download | 0.267 | 0.977 | chromatin silencing at telomere | a.4.1 | Homeodomain-like |
| View | Download | 0.264 | 0.977 | chromatin silencing at telomere | a.70.1 | N-terminal domain of the delta subunit of the F1F0-ATP synthase |
| View | Download | 0.253 | 0.977 | chromatin silencing at telomere | d.15.1 | Ubiquitin-like |
| View | Download | 0.242 | 0.977 | chromatin silencing at telomere | a.8.3 | Families 57/38 glycoside transferase middle domain |
| View | Download | 0.236 | 0.977 | chromatin silencing at telomere | a.52.1 | Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin |
| View | Download | 0.230 | 0.977 | chromatin silencing at telomere | a.28.3 | Retrovirus capsid protein C-terminal domain |
| View | Download | 0.229 | 0.977 | chromatin silencing at telomere | a.159.2 | FF domain |
| View | Download | 0.225 | 0.977 | chromatin silencing at telomere | a.48.3 | Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 |
| View | Download | 0.220 | 0.977 | chromatin silencing at telomere | a.60.1 | SAM/Pointed domain |
| View | Download | 0.213 | 0.977 | chromatin silencing at telomere | d.58.4 | Dimeric alpha+beta barrel |
| View | Download | 0.209 | 0.977 | chromatin silencing at telomere | a.60.2 | RuvA domain 2-like |
| View | Download | 0.208 | 0.977 | chromatin silencing at telomere | a.35.1 | lambda repressor-like DNA-binding domains |
| View | Download | 0.208 | 0.977 | chromatin silencing at telomere | a.60.2 | RuvA domain 2-like |
| View | Download | 0.206 | 0.977 | chromatin silencing at telomere | a.48.3 | Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 |
| View | Download | 0.206 | 0.977 | chromatin silencing at telomere | a.74.1 | Cyclin-like |
| View | Download | 0.201 | 0.977 | chromatin silencing at telomere | a.4.13 | Sigma3 and sigma4 domains of RNA polymerase sigma factors |
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Region A: Residues: [73-155] |
1 11 21 31 41 51
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1 SSHIHNKSLH EDSARALSWV DSLINRGKSI LTTLEKEDAL FERSLEEERQ RFQLHDSLMN 60
61 KYTGNSKSHQ RLIDLRKSQY GTD
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| Detection Method: | |
| Confidence: | 7.0 |
| Match: | 1c1gA_ |
| Description: | Tropomyosin |
Matching Structure (courtesy of the PDB): |
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Region A: Residues: [156-498] |
1 11 21 31 41 51
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1 TSFQNNDEIP LDSFISSPLP DAEDESSSNI DSDKDEDLEG KQSLIKDFDL ENDEYELSEE 60
61 EKNSDGQSSP SIMILSDEEY AEEGALQDVS NDEYAEEEGQ VERKNIGQEQ ANVENATQIS 120
121 SSDSSEGQNY SEGVEMELED DIDVESDAEK DESQGAEGTE HSVDFSKYMQ PRTDNTKIPV 180
181 IEKYESDEHK VHQRYSEDGA FDFGSVNISV DDESEDEESQ AESYSANAEN VYHHNEHELD 240
241 DKELIEDIES SDSESQSAQE SEQGSEDDFE YKMKNEKSTS EETENTSESR DQGFAKDAYT 300
301 KNKVEQQEND EEPEKDDIIR SSLDKNFHGN NNKSEYSENV LEN
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| Detection Method: | |
| Confidence: | 19.221849 |
| Match: | 1i84S_ |
| Description: | Heavy meromyosin subfragment |
Matching Structure (courtesy of the PDB): |
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Region A: Residues: [499-571] |
1 11 21 31 41 51
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1 ETDPAIVERE NQINDVEGYD VTGKSVESDL HEHSPDNLYD LAARAMLQFQ QSRNSNCPQK 60
61 EEQVSESYLG HSN
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| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
|
Region A: Residues: [572-629] |
1 11 21 31 41 51
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1 GSNLSGRSLD ESEEQIPLKD FTGENNNNLK TDRGDLSSSV EIEVEKVSEK KLDGSTEK
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| Detection Method: | |
| Confidence: | 7.30103 |
| Match: | 2tmaA_ |
| Description: | Tropomyosin |
Matching Structure (courtesy of the PDB): |
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Region A: Residues: [630-711] |
1 11 21 31 41 51
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1 ELVPLSTDTT INNSSLGNED SIYYSLDDAD AISENLTDVP LMEIKTTPKY EVVISESVYS 60
61 STSYEDNTVA MPPQVEYTSP FM
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| Detection Method: | |
| Confidence: | 7.30103 |
| Match: | 2tmaA_ |
| Description: | Tropomyosin |
| Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [712-773] |
1 11 21 31 41 51
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1 NDPFNSLNDD YEKKHDLLKS TLAALAPAFT KKDAEFVEAG VTKSCLTSTS GHTNIFHTSK 60
61 ET
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| Detection Method: | |
| Confidence: | 7.30103 |
| Match: | 2tmaA_ |
| Description: | Tropomyosin |
| Matching Structure (courtesy of the PDB): |
|
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Region A: Residues: [774-856] |
1 11 21 31 41 51
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1 KQVSDLDEST ENVTFENENT GDENKNQSKN FPGVANSTDK STEDNTDEKY FSAINYTNVT 60
61 GDSSCEDIIE TASNVEENLR YCE
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| Detection Method: | |
| Confidence: | 7.30103 |
| Match: | 2tmaA_ |
| Description: | Tropomyosin |
| Matching Structure (courtesy of the PDB): |
|
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Region A: Residues: [857-1197] |
1 11 21 31 41 51
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1 KDMNEAEMSS GDECVKQNDD GSKTQISFST DSPDNFQESN DNTEFSSTKY KVRNSDLEDD 60
61 ESLKKELTKA EVVDKLDEEE SEDSYEQDYA DPEPGNDEGS NENIVKGTKK DTLGIVEPEN 120
121 EKVNKVHEEE TLFEANVSSS VNVQNKDMHT DVINQEAQAN YEAGERKYYI QNTDTEEAHI 180
181 SIIERIDENA IGNNMEIPER SCVEKTHNEV LFERRATTIE NTKALENNTN MHDQVSQACS 240
241 DSDRDQDSTA EKNVEGSAKH NLDIRVSSSE IESVEPLKPE SDRSNIFSSP IRVIGAVVKG 300
301 VGKVVDVAES FVKKIDVMDS ESDDNVDIGD YNQDIFNKSN S
|
| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
|
Region A: Residues: [1198-1273] |
1 11 21 31 41 51
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1 TDASVNMKSV SSKERDSDED EAVILGGVTA EAHNDNGNNS RVINIDPTTN GAYEEDSEVF 60
61 RQQVKDKENL HKSEEP
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.768 | d.58.17 | Metal-binding domain |
| View | Download | 0.681 | d.58.4 | Dimeric alpha+beta barrel |
| View | Download | 0.721 | d.58.17 | Metal-binding domain |
| View | Download | 0.677 | d.50.2 | Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain |
| View | Download | 0.660 | d.58.3 | Protease propeptides/inhibitors |
| View | Download | 0.658 | d.129.2 | Phosphoglucomutase, C-terminal domain |
| View | Download | 0.639 | a.112.1 | Description not found. |
| View | Download | 0.627 | d.16.1 | FAD-linked reductases, C-terminal domain |
| View | Download | 0.614 | b.114.1 | N-utilization substance G protein NusG, insert domain |
| View | Download | 0.614 | d.16.1 | FAD-linked reductases, C-terminal domain |
| View | Download | 0.589 | d.93.1 | SH2 domain |
| View | Download | 0.581 | d.58.3 | Protease propeptides/inhibitors |
| View | Download | 0.568 | d.58.4 | Dimeric alpha+beta barrel |
| View | Download | 0.558 | d.58.17 | Metal-binding domain |
| View | Download | 0.556 | d.52.3 | Prokaryotic type KH domain (KH-domain type II) |
| View | Download | 0.541 | d.58.17 | Metal-binding domain |
| View | Download | 0.536 | d.58.44 | Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains |
| View | Download | 0.528 | b.55.1 | PH domain-like |
| View | Download | 0.522 | d.58.7 | RNA-binding domain, RBD |
| View | Download | 0.519 | d.58.44 | Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains |
| View | Download | 0.519 | d.16.1 | FAD-linked reductases, C-terminal domain |
| View | Download | 0.496 | d.58.44 | Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains |
| View | Download | 0.493 | d.10.1 | DNA-binding domain |
| View | Download | 0.492 | c.47.2 | RNA 3'-terminal phosphate cyclase, RPTC, insert domain |
| View | Download | 0.484 | b.36.1 | PDZ domain-like |
| View | Download | 0.477 | b.84.2 | Rudiment single hybrid motif |
| View | Download | 0.465 | d.58.12 | eEF-1beta-like |
| View | Download | 0.462 | d.51.1 | Eukaryotic type KH-domain (KH-domain type I) |
| View | Download | 0.456 | d.58.40 | D-ribose-5-phosphate isomerase (RpiA), lid domain |
| View | Download | 0.448 | d.58.3 | Protease propeptides/inhibitors |
| View | Download | 0.448 | d.129.2 | Phosphoglucomutase, C-terminal domain |
| View | Download | 0.445 | d.58.12 | eEF-1beta-like |
| View | Download | 0.431 | d.129.2 | Phosphoglucomutase, C-terminal domain |
| View | Download | 0.429 | d.58.17 | Metal-binding domain |
| View | Download | 0.412 | d.10.1 | DNA-binding domain |
| View | Download | 0.395 | c.55.7 | Methylated DNA-protein cysteine methyltransferase domain |
| View | Download | 0.394 | d.56.1 | GroEL-intermediate domain like |
| View | Download | 0.392 | d.58.24 | CheY-binding domain of CheA |
| View | Download | 0.391 | d.16.1 | FAD-linked reductases, C-terminal domain |
| View | Download | 0.390 | d.58.17 | Metal-binding domain |
| View | Download | 0.387 | b.1.14 | Invasin/intimin cell-adhesion fragments |
| View | Download | 0.377 | d.58.12 | eEF-1beta-like |
| View | Download | 0.376 | d.52.3 | Prokaryotic type KH domain (KH-domain type II) |
| View | Download | 0.376 | d.129.2 | Phosphoglucomutase, C-terminal domain |
| View | Download | 0.374 | d.129.2 | Phosphoglucomutase, C-terminal domain |
| View | Download | 0.371 | d.129.2 | Phosphoglucomutase, C-terminal domain |
| View | Download | 0.369 | d.16.1 | FAD-linked reductases, C-terminal domain |
| View | Download | 0.368 | d.58.18 | Regulatory domain in the aminoacid metabolism |
| View | Download | 0.368 | d.50.2 | Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain |
| View | Download | 0.364 | b.36.1 | PDZ domain-like |
| View | Download | 0.363 | d.54.1 | Enolase N-terminal domain-like |
| View | Download | 0.362 | c.102.1 | Cell-division inhibitor MinC, N-terminal domain |
| View | Download | 0.351 | b.55.1 | PH domain-like |
| View | Download | 0.349 | b.40.6 | MOP-like |
| View | Download | 0.349 | d.58.44 | Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains |
| View | Download | 0.348 | d.58.12 | eEF-1beta-like |
| View | Download | 0.342 | d.58.8 | Viral DNA-binding domain |
| View | Download | 0.342 | d.58.8 | Viral DNA-binding domain |
| View | Download | 0.341 | d.52.4 | YhbC-like, N-terminal domain |
| View | Download | 0.341 | d.58.18 | Regulatory domain in the aminoacid metabolism |
| View | Download | 0.340 | d.93.1 | SH2 domain |
| View | Download | 0.340 | d.16.1 | FAD-linked reductases, C-terminal domain |
| View | Download | 0.332 | b.1.2 | Fibronectin type III |
| View | Download | 0.327 | d.87.2 | CO dehydrogenase flavoprotein C-terminal domain-like |
| View | Download | 0.325 | d.93.1 | SH2 domain |
| View | Download | 0.320 | c.55.4 | Translational machinery components |
| View | Download | 0.320 | d.9.2 | Description not found. |
| View | Download | 0.317 | d.9.1 | Interleukin 8-like chemokines |
| View | Download | 0.315 | c.55.4 | Translational machinery components |
| View | Download | 0.314 | d.87.2 | CO dehydrogenase flavoprotein C-terminal domain-like |
| View | Download | 0.313 | d.58.18 | Regulatory domain in the aminoacid metabolism |
| View | Download | 0.312 | d.58.7 | RNA-binding domain, RBD |
| View | Download | 0.312 | d.16.1 | FAD-linked reductases, C-terminal domain |
| View | Download | 0.312 | d.16.1 | FAD-linked reductases, C-terminal domain |
| View | Download | 0.312 | b.55.1 | PH domain-like |
| View | Download | 0.311 | b.59.1 | XRCC4, N-terminal domain |
| View | Download | 0.308 | d.129.1 | TATA-box binding protein-like |
| View | Download | 0.307 | d.52.3 | Prokaryotic type KH domain (KH-domain type II) |
| View | Download | 0.306 | d.58.44 | Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains |
| View | Download | 0.303 | b.40.2 | Bacterial enterotoxins |
| View | Download | 0.299 | d.93.1 | SH2 domain |
| View | Download | 0.294 | c.47.2 | RNA 3'-terminal phosphate cyclase, RPTC, insert domain |
| View | Download | 0.293 | d.129.2 | Phosphoglucomutase, C-terminal domain |
| View | Download | 0.287 | c.55.4 | Translational machinery components |
| View | Download | 0.284 | d.222.1 | YbaB-like |
| View | Download | 0.278 | d.58.44 | Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains |
| View | Download | 0.278 | b.55.1 | PH domain-like |
| View | Download | 0.277 | d.214.1 | Hypothetical protein MTH1880 |
| View | Download | 0.277 | b.43.4 | Riboflavin synthase domain-like |
| View | Download | 0.271 | d.58.10 | Acylphosphatase-like |
| View | Download | 0.266 | d.58.18 | Regulatory domain in the aminoacid metabolism |
| View | Download | 0.263 | d.204.1 | Ribosome binding protein Y (YfiA homologue) |
| View | Download | 0.263 | d.10.1 | DNA-binding domain |
| View | Download | 0.259 | b.55.1 | PH domain-like |
| View | Download | 0.256 | b.3.5 | B repeat unit of collagen binding surface protein (cna) |
| View | Download | 0.256 | d.58.43 | Mechanosensitive channel protein MscS (YggB), C-terminal domain |
| View | Download | 0.252 | c.47.1 | Thioredoxin-like |
| View | Download | 0.248 | b.55.1 | PH domain-like |
| View | Download | 0.246 | d.129.2 | Phosphoglucomutase, C-terminal domain |
| View | Download | 0.245 | d.74.1 | Pterin-4a-carbinolamine dehydratase (PCD)/dimerization cofactor of HNF1 (DCoH) |
| View | Download | 0.243 | d.129.2 | Phosphoglucomutase, C-terminal domain |
| View | Download | 0.241 | d.129.2 | Phosphoglucomutase, C-terminal domain |
| View | Download | 0.239 | d.58.12 | eEF-1beta-like |
| View | Download | 0.237 | b.1.1 | Immunoglobulin |
| View | Download | 0.233 | d.192.1 | YlxR-like |
| View | Download | 0.229 | d.58.18 | Regulatory domain in the aminoacid metabolism |
| View | Download | 0.226 | g.41.3 | Zinc beta-ribbon |
| View | Download | 0.225 | d.16.1 | FAD-linked reductases, C-terminal domain |
| View | Download | 0.223 | d.58.2 | Aspartate carbamoyltransferase, Regulatory-chain, N-terminal domain |
| View | Download | 0.222 | c.51.3 | B12-dependend dehydatases associated subunit |
| View | Download | 0.220 | d.58.12 | eEF-1beta-like |
| View | Download | 0.219 | b.40.2 | Bacterial enterotoxins |
| View | Download | 0.218 | b.1.14 | Invasin/intimin cell-adhesion fragments |
| View | Download | 0.212 | d.93.1 | SH2 domain |
| View | Download | 0.210 | d.110.4 | SNARE-like |
| View | Download | 0.208 | d.41.3 | Pyrimidine nucleoside phosphorylase C-terminal domain |
| View | Download | 0.208 | d.58.10 | Acylphosphatase-like |
| View | Download | 0.207 | d.93.1 | SH2 domain |
| View | Download | 0.205 | d.93.1 | SH2 domain |
| View | Download | 0.201 | d.58.42 | N-utilization substance G protein NusG, N-terminal domain |
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Region A: Residues: [1274-1342] |
1 11 21 31 41 51
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1 LVEGLQSEQH FEKKDHSENE EEFDTIYGDI TSANIHSNAP DDIKRQQLLK NLSDLENYSQ 60
61 RLIEDSRRG
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| Detection Method: | |
| Confidence: | 14.86 |
| Match: | 1l8mA |
| Description: | No description for 1l8mA was found. |
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Region A: Residues: [1343-1658] |
1 11 21 31 41 51
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1 KNQEESDEVN TSRERDLTFE KSVNEKYAGA IEEDTFSELD ISIQHPEHEE DLDLSNNQER 60
61 SIEELNSEPE EAELYELEIE GPTETAASSK MNDDERQRGN IPSTDLPSDP PSDKEEVTDS 120
121 YPYSNSENIT AEKSAPTSPE VYEIFSDTPN EVPMEINDEI PATTLEKHDK TNVTSVLDDR 180
181 SEHLSSHDVD NEPHDNSINI KVNEGEEPEH QAVDIPVKVE VKEEQEEMPS KSVLEEQKPS 240
241 MELINDKSSP ENNNDEETNR EKDKTKAKKK SRKRNYNSRR RKRKITEGSS AASNTKRRRG 300
301 HEPKSRGQNT HPSVDK
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| Detection Method: | |
| Confidence: | 9.71 |
| Match: | 1m2vB |
| Description: | Sec24 |
Matching Structure (courtesy of the PDB): |
|
