YRC Public Data Repository - Protein Structure Prediction

Protein:	CEF1
Organism:	Saccharomyces cerevisiae
Length:	590 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CEF1.

Description	E-value	Query Range	Subject Range
CEF1 - Essential splicing factor; associated with Prp19p and the spliceosome, contains an N-terminal c-Myb ... CEF1_YEAST - Pre-mRNA-splicing factor CEF1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=CEF1 PE=1 ...	0.0	[1..590]	[1..590]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	8.0E-87	[6..412]	[104..526]
gi\|15375301 - gi\|15375301\|gb\|AAK54740.2\|AF371976_1 putative c-myb-like transcription factor MYB3R-5 [Arabidopsis t...	5.0E-86	[6..412]	[123..545]
gi\|220951728 - gi\|220951728\|gb\|ACL88407.1\| CG6905-PA [synthetic construct] CG6905-PA, CG6905-PB - This gene is referred to in FlyBase by the symbol Dmel\CG6905 (CG6905, FBgn0035136). It is a protein...	2.0E-80	[1..362]	[1..349]
CDC5L - CDC5 cell division cycle 5-like (S. pombe) gi\|123996277, gi... - gi\|123996277\|gb\|ABM85740.1\| CDC5 cell division cycle 5-like (S. pombe) [synthetic construct], gi\|123...	1.0E-78	[1..365]	[1..360]
CDC5L_RAT - Cell division cycle 5-like protein OS=Rattus norvegicus GN=Cdc5l PE=1 SV=2	7.0E-78	[1..365]	[1..360]

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Predicted Domain #1

Region A:
Residues: [1-61]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPPVPIYVKG GVWTNVEDQI LKAAVQKYGT HQWSKVASLL QKKTARQSEL RWNEYLNPKL  60
   61 N

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	144.927757
Match:	1mseC_
Description:	c-Myb, DNA-binding domain
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [62-117]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FTEFSKEEDA QLLDLARELP NQWRTIADMM ARPAQVCVER YNRLLESEDS GGAALS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	144.927757
Match:	1mseC_
Description:	c-Myb, DNA-binding domain
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [118-590]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TGVTDLKAGD INPNAETQMA RPDNGDLEDE EKEMLAEARA RLLNTQGKKA TRKIRERMLE  60
   61 ESKRIAELQK RRELKQAGIN VAIKKPKKKY GTDIDYNEDI VYEQAPMPGI YDTSTEDRQI 120
  121 KKKFEQFERK VNRKGLDGNK DKPSKKNKDK KRKHDENEHV EKAALGESTT LTDEYKKPKL 180
  181 ILSAPGTKQG KVTYKKKLES KRQKLIEAQA TGTVLTPKEL LPHDSGQEDN ERSNIKSGKQ 240
  241 LKSRIRKFLV QMFASLPSPK NDFEIVLSED EKEEDAEIAE YEKEFENERA MNEEDNFIEP 300
  301 PSQNDAPRVS LVAVPLAYST LPIPEFKNNP QSAIDNKYNL LVANAINKEP HMVPEDTVDF 360
  361 LKEVESRMQH ITQGRTSMKI QFKTAMPPTE VLLESIQSKV ESIEQLQRKL QHVQPLEQQN 420
  421 NEMCSTLCHH SLPALIEGQR KYYADYYAYR QEIRSLEGRR KRLQAMLNSS SSI

[Run NCBI BLAST on this sequence.]

Detection Method:	Pcons
Confidence:	1.74
Match:	1cii_
Description:	Colicin Ia; Colicin Ia, N-terminal domain
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits