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View Structure Prediction Details

Protein: CIK1
Organism: Saccharomyces cerevisiae
Length: 594 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CIK1.

Description E-value Query
Range		 Subject
Range
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
 2.0E-62 [2..512] [204..725]
gi|45383668, gi|... - gi|9800486|gb|AAF99314.1|AF272033_1 fast myosin heavy chain isoform 2 [Gallus gallus], gi|45383668|r...
 2.0E-62 [2..512] [1193..1714]
MYH1 - myosin, heavy chain 1, skeletal muscle, adult
 9.0E-62 [2..512] [1189..1710]
gi|8250661 - gi|8250661|gb|AAB29713.2| myosin heavy chain [Rattus sp.]
 1.0E-61 [2..512] [142..663]

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Predicted Domain #1
Region A:
Residues: [1-362] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNNSKIPKLS FHSDPNNVTR DFPKTKRQKV QKREMDMILT PNNNKLNILH SSGSGIRRCY  60
   61 TDDTSATYTK KLTFGGDPKI IERVKNNERK VRKDIDSLLN AISEIEKESV RIHARELPAI 120
  121 TLELDAKVKA CRELQNEIDG LSTEMDLKDN QCDLQRKNVE LSSKNIVSMH AVKVQEFEND 180
  181 LEEELSNAKR EWTYKLMEVE NLKPDERLTD EMRQLKTEFE EVNRKLFILQ NENENECKNY 240
  241 KKELDKKFEI FKKVKNDARI ELDGEQERLS KVLKDLQDTH GELKENIKTC RDEFNDFEKR 300
  301 IGEAEVNFHS MELAVVPLKK KLASTSQALT QVQEEKKQVE GEANNWKKKY VNELEKVQQE 360
  361 LY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 13.69897
Match: 1i84S_
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [363-406] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TRQNLATSIE EIKGYTRCFA YANERQMPDE FHINYVDRCI CENS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 9.30103
Match: 2tmaA_
Description: Tropomyosin
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [407-523] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GEKRVQVFDR VVLEEIHKDH KRLYNECIPF LEKYISKLIN CSIIVVSQQP TAPMKKTLLK  60
   61 QLIEQYGENY KMTLNILHLD GSIKHSDVGL DNPTEIRDLS QDEECMNILT LDTKLGK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 9.30103
Match: 2tmaA_
Description: Tropomyosin
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [524-594] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DEESHSMNIY IGSMSTVQLN RELDDAPSVL SHILTKTKQC FVFKINAGEN IEKALALAGK  60
   61 LKRTITLPQL D

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score		 SCOP
Match		 SCOP Description
View Download 0.663 d.68.3 SirA-like
View Download 0.643 d.68.4 YhbY-like
View Download 0.642 d.68.3 SirA-like
View Download 0.608 c.102.1 Cell-division inhibitor MinC, N-terminal domain
View Download 0.567 d.68.3 SirA-like
View Download 0.555 d.15.1 Ubiquitin-like
View Download 0.543 c.102.1 Cell-division inhibitor MinC, N-terminal domain
View Download 0.533 c.55.4 Translational machinery components
View Download 0.532 d.68.3 SirA-like
View Download 0.524 d.68.3 SirA-like
View Download 0.523 c.59.1 MurD-like peptide ligases, peptide-binding domain
View Download 0.514 d.68.3 SirA-like
View Download 0.511 d.15.1 Ubiquitin-like
View Download 0.499 d.15.1 Ubiquitin-like
View Download 0.495 d.68.3 SirA-like
View Download 0.494 d.15.1 Ubiquitin-like
View Download 0.491 d.68.4 YhbY-like
View Download 0.468 d.15.1 Ubiquitin-like
View Download 0.466 c.58.1 Aminoacid dehydrogenase-like, N-terminal domain
View Download 0.458 d.15.2 CAD & PB1 domains
View Download 0.446 d.15.2 CAD & PB1 domains
View Download 0.444 c.9.1 Barstar (barnase inhibitor)
View Download 0.436 c.13.2 Anti-sigma factor antagonist SpoIIaa
View Download 0.422 d.68.6 DNA-binding protein Sso10b (AlbA)
View Download 0.421 d.68.3 SirA-like
View Download 0.419 d.68.6 DNA-binding protein Sso10b (AlbA)
View Download 0.417 d.68.3 SirA-like
View Download 0.415 d.74.2 C-terminal domain of arginine repressor
View Download 0.410 d.68.3 SirA-like
View Download 0.401 d.15.1 Ubiquitin-like
View Download 0.401 d.74.2 C-terminal domain of arginine repressor
View Download 0.395 d.15.2 CAD & PB1 domains
View Download 0.394 d.15.2 CAD & PB1 domains
View Download 0.393 d.15.3 MoaD/ThiS
View Download 0.382 d.15.1 Ubiquitin-like
View Download 0.382 b.71.1 Glycosyl hydrolase domain
View Download 0.381 d.15.1 Ubiquitin-like
View Download 0.378 d.68.3 SirA-like
View Download 0.378 d.15.7 Immunoglobulin-binding domains
View Download 0.378 d.15.7 Immunoglobulin-binding domains
View Download 0.375 d.15.7 Immunoglobulin-binding domains
View Download 0.373 c.102.1 Cell-division inhibitor MinC, N-terminal domain
View Download 0.367 c.59.1 MurD-like peptide ligases, peptide-binding domain
View Download 0.361 d.15.2 CAD & PB1 domains
View Download 0.360 d.15.2 CAD & PB1 domains
View Download 0.359 a.4.1 Homeodomain-like
View Download 0.357 d.15.2 CAD & PB1 domains
View Download 0.356 c.102.1 Cell-division inhibitor MinC, N-terminal domain
View Download 0.349 c.58.1 Aminoacid dehydrogenase-like, N-terminal domain
View Download 0.348 d.15.1 Ubiquitin-like
View Download 0.346 d.15.1 Ubiquitin-like
View Download 0.345 d.15.1 Ubiquitin-like
View Download 0.342 c.102.1 Cell-division inhibitor MinC, N-terminal domain
View Download 0.339 d.68.4 YhbY-like
View Download 0.338 d.15.7 Immunoglobulin-binding domains
View Download 0.337 d.15.7 Immunoglobulin-binding domains
View Download 0.337 d.15.7 Immunoglobulin-binding domains
View Download 0.335 d.15.2 CAD & PB1 domains
View Download 0.331 c.46.1 Rhodanese/Cell cycle control phosphatase
View Download 0.331 c.102.1 Cell-division inhibitor MinC, N-terminal domain
View Download 0.329 d.15.2 CAD & PB1 domains
View Download 0.324 d.15.1 Ubiquitin-like
View Download 0.323 d.15.7 Immunoglobulin-binding domains
View Download 0.315 c.55.4 Translational machinery components
View Download 0.305 c.58.1 Aminoacid dehydrogenase-like, N-terminal domain
View Download 0.304 d.15.2 CAD & PB1 domains
View Download 0.304 d.15.2 CAD & PB1 domains
View Download 0.302 c.37.1 P-loop containing nucleoside triphosphate hydrolases
View Download 0.302 c.2.1 NAD(P)-binding Rossmann-fold domains
View Download 0.301 c.30.1 PreATP-grasp domain
View Download 0.294 d.15.7 Immunoglobulin-binding domains
View Download 0.292 d.169.1 C-type lectin-like
View Download 0.289 d.15.3 MoaD/ThiS
View Download 0.288 d.15.2 CAD & PB1 domains
View Download 0.287 b.71.1 Glycosyl hydrolase domain
View Download 0.286 c.102.1 Cell-division inhibitor MinC, N-terminal domain
View Download 0.285 b.71.1 Glycosyl hydrolase domain
View Download 0.282 d.68.6 DNA-binding protein Sso10b (AlbA)
View Download 0.281 c.9.1 Barstar (barnase inhibitor)
View Download 0.276 c.102.1 Cell-division inhibitor MinC, N-terminal domain
View Download 0.274 c.55.4 Translational machinery components
View Download 0.273 c.48.1 TK C-terminal domain-like
View Download 0.272 d.15.7 Immunoglobulin-binding domains
View Download 0.269 c.58.1 Aminoacid dehydrogenase-like, N-terminal domain
View Download 0.267 c.59.1 MurD-like peptide ligases, peptide-binding domain
View Download 0.266 d.37.1 CBS-domain
View Download 0.265 c.55.4 Translational machinery components
View Download 0.262 d.68.3 SirA-like
View Download 0.260 c.59.1 MurD-like peptide ligases, peptide-binding domain
View Download 0.259 a.11.1 Acyl-CoA binding protein
View Download 0.253 c.13.2 Anti-sigma factor antagonist SpoIIaa
View Download 0.248 d.94.1 HPr-like
View Download 0.246 d.37.1 CBS-domain
View Download 0.246 d.94.1 HPr-like
View Download 0.244 c.78.2 Aspartate/glutamate racemase
View Download 0.243 d.15.2 CAD & PB1 domains
View Download 0.243 c.37.1 P-loop containing nucleoside triphosphate hydrolases
View Download 0.243 d.109.1 Actin depolymerizing proteins
View Download 0.242 c.102.1 Cell-division inhibitor MinC, N-terminal domain
View Download 0.240 c.58.1 Aminoacid dehydrogenase-like, N-terminal domain
View Download 0.234 c.55.7 Methylated DNA-protein cysteine methyltransferase domain
View Download 0.232 b.1.18 E set domains
View Download 0.230 d.76.1 GYF domain
View Download 0.229 c.3.1 FAD/NAD(P)-binding domain
View Download 0.227 c.30.1 PreATP-grasp domain
View Download 0.226 c.97.1 Cytidine deaminase-like
View Download 0.225 d.68.3 SirA-like
View Download 0.224 c.46.1 Rhodanese/Cell cycle control phosphatase
View Download 0.223 d.68.4 YhbY-like
View Download 0.223 d.15.1 Ubiquitin-like
View Download 0.223 c.10.2 L domain-like
View Download 0.223 c.13.2 Anti-sigma factor antagonist SpoIIaa
View Download 0.220 d.109.1 Actin depolymerizing proteins
View Download 0.219 d.58.3 Protease propeptides/inhibitors
View Download 0.216 c.52.1 Restriction endonuclease-like
View Download 0.216 c.102.1 Cell-division inhibitor MinC, N-terminal domain
View Download 0.215 d.94.1 HPr-like
View Download 0.213 c.13.2 Anti-sigma factor antagonist SpoIIaa
View Download 0.212 c.23.6 Cobalamin (vitamin B12)-binding domain
View Download 0.209 c.5.1 MurCD N-terminal domain
View Download 0.208 d.94.1 HPr-like
View Download 0.205 c.10.2 L domain-like
View Download 0.202 c.13.2 Anti-sigma factor antagonist SpoIIaa
View Download 0.202 b.1.2 Fibronectin type III
View Download 0.202 c.102.1 Cell-division inhibitor MinC, N-terminal domain

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle