YRC Public Data Repository - Protein Structure Prediction

Protein:	SNO1
Organism:	Saccharomyces cerevisiae
Length:	224 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SNO1.

Description	E-value	Query Range	Subject Range
gi\|190408324 - gi\|190408324\|gb\|EDV11589.1\| conserved hypothetical protein [Saccharomyces cerevisiae RM11-1a] gi\|207342337 - gi\|207342337\|gb\|EDZ70128.1\| YMR095Cp-like protein [Saccharomyces cerevisiae AWRI1631] SNO1 - Protein of unconfirmed function, involved in pyridoxine metabolism; expression is induced during sta... SNO1_YEAST - Pyridoxal 5'-phosphate synthase subunit SNO1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c...	3.0E-45	[1..224]	[1..224]
PYRG_CLOAB - CTP synthase OS=Clostridium acetobutylicum GN=pyrG PE=3 SV=1 PYRG_CLOAB - CTP synthase OS=Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-...	4.0E-40	[7..222]	[285..527]
PYRG_BACHD - CTP synthase OS=Bacillus halodurans GN=pyrG PE=3 SV=1 PYRG_BACHD - CTP synthase OS=Bacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125)...	1.0E-38	[6..224]	[284..529]
PYRG_LISMO - CTP synthase OS=Listeria monocytogenes GN=pyrG PE=3 SV=1 gi\|224500487 - gi\|224500487\|ref\|ZP_03668836.1\| CTP synthetase [Listeria monocytogenes Finland 1988] gi\|224503651 - gi\|224503651\|ref\|ZP_03671958.1\| CTP synthetase [Listeria monocytogenes FSL R2-561] gi\|153192239, gi... - gi\|153192239\|ref\|ZP_01939259.1\| CTP synthase [Listeria monocytogenes J2818], gi\|127764299\|gb\|EBA2483... gi\|133729042, gi... - gi\|153175829\|ref\|ZP_01931116.1\| CTP synthase [Listeria monocytogenes FSL N3-165], gi\|133729042\|gb\|EB... gi\|254938185, gi... - gi\|254938185\|ref\|ZP_05269882.1\| CTP synthetase [Listeria monocytogenes F6900], gi\|153180671\|ref\|ZP_0... gi\|47097102, gi\|... - gi\|47097102\|ref\|ZP_00234671.1\| CTP synthase [Listeria monocytogenes str. 1/2a F6854], gi\|47014507\|gb... PYRG_LISMO - CTP synthase OS=Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e) GN=pyrG PE=3 SV=1 gi\|254900990 - gi\|254900990\|ref\|ZP_05260914.1\| CTP synthetase [Listeria monocytogenes J0161]	1.0E-38	[5..224]	[282..531]
PYRG_CLOPE - CTP synthase OS=Clostridium perfringens GN=pyrG PE=3 SV=1 gi\|170662852, gi... - gi\|170662852\|gb\|EDT15535.1\| CTP synthase [Clostridium perfringens E str. JGS1987], gi\|168205555\|ref\|... gi\|168210137, gi... - gi\|170711780\|gb\|EDT23962.1\| CTP synthase [Clostridium perfringens B str. ATCC 3626], gi\|168210137\|re... gi\|170714836, gi... - gi\|170714836\|gb\|EDT27018.1\| CTP synthase [Clostridium perfringens CPE str. F4969], gi\|168213688\|ref\|... PYRG_CLOP1 - CTP synthase OS=Clostridium perfringens (strain ATCC 13124 / DSM 756 / JCM 1290 / NCIMB 6125 / NCTC ... PYRG_CLOPS - CTP synthase OS=Clostridium perfringens (strain SM101 / Type A) GN=pyrG PE=3 SV=1 PYRG_CLOPE - CTP synthase OS=Clostridium perfringens (strain 13 / Type A) GN=pyrG PE=3 SV=1 gi\|169297657, gi... - gi\|169344199\|ref\|ZP_02865181.1\| CTP synthase [Clostridium perfringens C str. JGS1495], gi\|169297657\|...	4.0E-38	[5..221]	[285..528]
PYRG_LISIN - CTP synthase OS=Listeria innocua GN=pyrG PE=3 SV=1 PYRG_LISIN - CTP synthase OS=Listeria innocua serovar 6a (strain CLIP 11262) GN=pyrG PE=3 SV=1	2.0E-37	[5..221]	[282..525]
PYRG_STAA9 - CTP synthase OS=Staphylococcus aureus (strain JH9) GN=pyrG PE=3 SV=1 PYRG_STAA1 - CTP synthase OS=Staphylococcus aureus (strain Mu3 / ATCC 700698) GN=pyrG PE=3 SV=1 PYRG_STAAE - CTP synthase OS=Staphylococcus aureus (strain Newman) GN=pyrG PE=3 SV=1 PYRG_STAAC - CTP synthase OS=Staphylococcus aureus (strain COL) GN=pyrG PE=3 SV=1 PYRG_STAAM - CTP synthase OS=Staphylococcus aureus (strain Mu50 / ATCC 700699) GN=pyrG PE=3 SV=1 PYRG_STAAN - CTP synthase OS=Staphylococcus aureus (strain N315) GN=pyrG PE=1 SV=1 PYRG_STAAW - CTP synthase OS=Staphylococcus aureus (strain MW2) GN=pyrG PE=3 SV=1 gi\|255006915 - gi\|255006915\|ref\|ZP_05145516.2\| CTP synthetase [Staphylococcus aureus subsp. aureus Mu50-omega] gi\|253733039, gi... - gi\|253733039\|ref\|ZP_04867204.1\| CTP synthetase [Staphylococcus aureus subsp. aureus TCH130], gi\|2537... gi\|253731035, gi... - gi\|253731035\|ref\|ZP_04865200.1\| CTP synthetase [Staphylococcus aureus subsp. aureus USA300_TCH959], ... gi\|253315796 - gi\|253315796\|ref\|ZP_04839009.1\| CTP synthetase [Staphylococcus aureus subsp. aureus str. CF-Marseill... gi\|251812302, gi... - gi\|251812302\|ref\|ZP_04826775.1\| CTP synthetase [Staphylococcus aureus subsp. aureus TCH70], gi\|25180... gi\|227899529, gi... - gi\|227899529\|ref\|ZP_04017334.1\| CTP synthetase [Staphylococcus aureus subsp. aureus TCH60], gi\|22785... PYRG_STAAS - CTP synthase OS=Staphylococcus aureus (strain MSSA476) GN=pyrG PE=3 SV=1 gi\|227558785, gi... - gi\|227558785\|ref\|ZP_03988832.1\| CTP synthetase [Staphylococcus aureus subsp. aureus MN8], gi\|2272447... gi\|25293724 - pir\|\|D90006 CTP synthase [imported] - Staphylococcus aureus (strain N315) PYRG_STAAR - CTP synthase OS=Staphylococcus aureus (strain MRSA252) GN=pyrG PE=3 SV=1 PYRG_STAA3 - CTP synthase OS=Staphylococcus aureus (strain USA300) GN=pyrG PE=3 SV=1 PYRG_STAAB - CTP synthase OS=Staphylococcus aureus (strain bovine RF122 / ET3-1) GN=pyrG PE=3 SV=1 gi\|269203763\|ref... - CTP synthetase [Staphylococcus aureus subsp. aureus ED98] PYRG_STAAT - CTP synthase OS=Staphylococcus aureus (strain USA300 / TCH1516) GN=pyrG PE=3 SV=1 gi\|221137025 - gi\|221137025\|ref\|ZP_03561836.1\| CTP synthetase [Staphylococcus aureus subsp. aureus str. JKD6008] gi\|221141646 - gi\|221141646\|ref\|ZP_03566139.1\| CTP synthetase [Staphylococcus aureus subsp. aureus str. JKD6009] gi\|87126527\|gb\|A... - CTP synthase [Staphylococcus aureus subsp. aureus USA300], CTP synthase [Staphylococcus aureus subsp... PYRG_STAA2 - CTP synthase OS=Staphylococcus aureus (strain JH1) GN=pyrG PE=3 SV=1	5.0E-37	[2..224]	[280..529]
PYRG_LACLA - CTP synthase OS=Lactococcus lactis subsp. lactis GN=pyrG PE=3 SV=1 PYRG_LACLA - CTP synthase OS=Lactococcus lactis subsp. lactis (strain IL1403) GN=pyrG PE=3 SV=1	2.0E-36	[7..222]	[285..528]
PYRG_ANAVT - CTP synthase OS=Anabaena variabilis (strain ATCC 29413 / PCC 7937) GN=pyrG PE=3 SV=1 PYRG_NOSS1 - CTP synthase OS=Nostoc sp. (strain PCC 7120 / UTEX 2576) GN=pyrG PE=3 SV=1 gi\|25293734 - pir\|\|AH2430 CTP synthetase [imported] - Nostoc sp. (strain PCC 7120)	2.0E-36	[1..221]	[274..525]
PYRG_ARCFU - CTP synthase OS=Archaeoglobus fulgidus GN=pyrG PE=3 SV=1 PYRG_ARCFU - CTP synthase OS=Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 10012...	2.0E-36	[6..222]	[280..521]

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Predicted Domain #1

Region A:
Residues: [1-224]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHKTHSTMSG KSMKVIGVLA LQGAFLEHTN HLKRCLAEND YGIKIEIKTV KTPEDLAQCD  60
   61 ALIIPGGEST SMSLIAQRTG LYPCLYEFVH NPEKVVWGTC AGLIFLSAQL ENESALVKTL 120
  121 GVLKVDVRRN AFGRQAQSFT QKCDFSNFIP GCDNFPATFI RAPVIERILD PIAVKSLYEL 180
  181 PVNGKDVVVA ATQNHNILVT SFHPELADSD TRFHDWFIRQ FVSN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	34.0
Match:	1gpmA_
Description:	GMP synthetase; GMP synthetase, central domain; GMP synthetase C-terminal dimerisation domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.30391542469987	bayes_pls_golite062009
binding	0.799270855996775	bayes_pls_golite062009
ligase activity	0.606811845310629	bayes_pls_golite062009
anthranilate synthase activity	0.198608229600186	bayes_pls_golite062009
protein binding	0.0152024556625711	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: