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View Structure Prediction Details

Protein: TAP42
Organism: Saccharomyces cerevisiae
Length: 366 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TAP42.

Description E-value Query
Range
Subject
Range
gi|190408266 - gi|190408266|gb|EDV11531.1| protein TAP42 [Saccharomyces cerevisiae RM11-1a]
TAP42 - Essential protein involved in the TOR signaling pathway; physically associates with the protein phos...
TAP42_YEAST - Type 2A phosphatase-associated protein 42 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) G...
0.0 [1..366] [1..366]
gi|61359007, gi|... - gi|61359015|gb|AAX41655.1| immunoglobulin binding protein 1 [synthetic construct], gi|61359007|gb|AA...
IGBP1 - immunoglobulin (CD79A) binding protein 1
0.0 [16..366] [23..339]
IGBP1_RAT - Immunoglobulin-binding protein 1 OS=Rattus norvegicus GN=Igbp1 PE=2 SV=2
0.0 [14..366] [22..340]
IGBP1_MOUSE - Immunoglobulin-binding protein 1 OS=Mus musculus GN=Igbp1 PE=1 SV=1
0.0 [14..366] [22..340]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
4.0E-79 [23..361] [44..372]
TAP46_ARATH - PP2A regulatory subunit TAP46 OS=Arabidopsis thaliana GN=TAP46 PE=1 SV=2
9.0E-75 [25..361] [25..398]
YCJ5_SCHPO - Uncharacterized protein C63.05 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPCC63.05 P...
SPCC63.05 - TAP42 family protein
2.0E-72 [13..366] [3..323]

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Predicted Domain #1
Region A:
Residues: [1-90]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASVTEQFND IISLYSTKLE HTSLRQDSPE YQGLLLSTIK KLLNLKTAIF DRLALFSTNE  60
   61 TIDDVSTASI KFLAVDYYLG LLISRRQSND 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.943 N/A N/A a.7.2 Enzyme IIa from lactose specific PTS, IIa-lac
View Download 0.807 N/A N/A a.23.1 HSC20 (HSCB), C-terminal oligomerisation domain
View Download 0.797 N/A N/A a.24.12 Outer surface protein C (OspC)
View Download 0.792 N/A N/A a.7.3 Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain
View Download 0.754 N/A N/A a.47.2 t-snare proteins
View Download 0.733 N/A N/A a.13.1 alpha-2-Macroglobulin receptor associated protein (RAP) domain 1
View Download 0.720 N/A N/A a.47.2 t-snare proteins
View Download 0.689 N/A N/A a.7.3 Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain
View Download 0.670 N/A N/A f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.649 N/A N/A a.24.2 Aspartate receptor, ligand-binding domain
View Download 0.646 N/A N/A a.4.9 Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3
View Download 0.642 N/A N/A a.24.9 alpha-catenin/vinculin
View Download 0.635 N/A N/A a.24.4 Hemerythrin
View Download 0.604 N/A N/A a.22.1 Histone-fold
View Download 0.602 N/A N/A a.2.7 tRNA-binding arm
View Download 0.594 N/A N/A a.22.1 Histone-fold
View Download 0.588 N/A N/A f.15.1 Small-conductance potassium channel
View Download 0.572 N/A N/A a.22.1 Histone-fold
View Download 0.562 N/A N/A a.7.1 Spectrin repeat
View Download 0.561 N/A N/A a.7.1 Spectrin repeat
View Download 0.544 N/A N/A a.2.11 Fe,Mn superoxide dismutase (SOD), N-terminal domain
View Download 0.540 N/A N/A a.25.1 Ferritin-like
View Download 0.510 N/A N/A a.47.2 t-snare proteins
View Download 0.507 N/A N/A f.13.1 Family A G protein-coupled receptor-like
View Download 0.481 N/A N/A a.7.8 GAT domain
View Download 0.466 N/A N/A a.22.1 Histone-fold
View Download 0.457 N/A N/A a.19.1 Fertilization protein
View Download 0.449 N/A N/A a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.443 N/A N/A a.30.2 Homodimeric domain of signal transducing histidine kinase
View Download 0.442 N/A N/A f.14.1 Voltage-gated potassium channels
View Download 0.427 N/A N/A a.7.7 BAG domain
View Download 0.425 N/A N/A f.17.1 F1F0 ATP synthase subunit C
View Download 0.424 N/A N/A a.24.3 Cytochromes
View Download 0.420 N/A N/A a.2.6 Effector domain of the protein kinase pkn/prk1
View Download 0.412 N/A N/A a.24.9 alpha-catenin/vinculin
View Download 0.411 N/A N/A a.7.5 Tubulin chaperone cofactor A
View Download 0.410 N/A N/A a.7.7 BAG domain
View Download 0.400 N/A N/A a.2.11 Fe,Mn superoxide dismutase (SOD), N-terminal domain
View Download 0.398 N/A N/A a.2.7 tRNA-binding arm
View Download 0.393 N/A N/A a.156.1 S13-like H2TH domain
View Download 0.386 N/A N/A a.46.1 Methionine synthase domain
View Download 0.386 N/A N/A f.34.1 Mechanosensitive channel protein MscS (YggB), transmembrane region
View Download 0.385 N/A N/A a.24.3 Cytochromes
View Download 0.384 N/A N/A a.24.16 Nucleotidyltransferase substrate binding subunit/domain
View Download 0.380 N/A N/A a.2.11 Fe,Mn superoxide dismutase (SOD), N-terminal domain
View Download 0.379 N/A N/A d.6.1 Prion-like
View Download 0.379 N/A N/A a.28.3 Retrovirus capsid protein C-terminal domain
View Download 0.372 N/A N/A a.63.1 Apolipophorin-III
View Download 0.371 N/A N/A f.35.1 Multidrug efflux transporter AcrB transmembrane domain
View Download 0.365 N/A N/A a.30.1 ROP protein
View Download 0.362 N/A N/A f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.361 N/A N/A i.11.1 Computational models partly based on NMR data
View Download 0.359 N/A N/A f.31.1 Photosystem I reaction center subunit XI, PsaL
View Download 0.340 N/A N/A a.39.1 EF-hand
View Download 0.340 N/A N/A a.39.1 EF-hand
View Download 0.339 N/A N/A a.79.1 Antitermination factor NusB
View Download 0.331 N/A N/A f.1.3 delta-Endotoxin (insectocide), N-terminal domain
View Download 0.317 N/A N/A f.28.1 Nonheme 11 kDa protein of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)
View Download 0.316 N/A N/A a.60.8 HRDC-like
View Download 0.306 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.305 N/A N/A a.121.1 Tetracyclin repressor-like, C-terminal domain
View Download 0.296 N/A N/A a.24.17 Group V grass pollen allergen
View Download 0.294 N/A N/A a.24.14 FAT domain of focal adhesion kinase
View Download 0.290 N/A N/A a.30.2 Homodimeric domain of signal transducing histidine kinase
View Download 0.285 N/A N/A c.55.1 Actin-like ATPase domain
View Download 0.280 N/A N/A a.29.3 Acyl-CoA dehydrogenase C-terminal domain-like
View Download 0.280 N/A N/A a.19.1 Fertilization protein
View Download 0.278 N/A N/A f.16.1 Gated mechanosensitive channel
View Download 0.269 N/A N/A a.2.1 GreA transcript cleavage protein, N-terminal domain
View Download 0.269 N/A N/A a.135.1 Tetraspanin
View Download 0.268 N/A N/A a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.266 N/A N/A c.55.4 Translational machinery components
View Download 0.265 N/A N/A a.26.1 4-helical cytokines
View Download 0.265 N/A N/A a.142.1 PTS-regulatory domain, PRD
View Download 0.264 N/A N/A a.11.1 Acyl-CoA binding protein
View Download 0.263 N/A N/A a.121.1 Tetracyclin repressor-like, C-terminal domain
View Download 0.261 N/A N/A a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.259 N/A N/A a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.256 N/A N/A a.7.1 Spectrin repeat
View Download 0.254 N/A N/A d.49.1 Signal recognition particle alu RNA binding heterodimer, SRP9/14
View Download 0.253 N/A N/A a.29.3 Acyl-CoA dehydrogenase C-terminal domain-like
View Download 0.250 N/A N/A a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.244 N/A N/A a.74.1 Cyclin-like
View Download 0.243 N/A N/A d.150.1 4'-phosphopantetheinyl transferase
View Download 0.242 N/A N/A a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.241 N/A N/A a.4.1 Homeodomain-like
View Download 0.239 N/A N/A a.3.1 Cytochrome c
View Download 0.235 N/A N/A a.24.15 FAD-dependent thiol oxidase
View Download 0.235 N/A N/A a.39.1 EF-hand
View Download 0.235 N/A N/A c.2.1 NAD(P)-binding Rossmann-fold domains
View Download 0.234 N/A N/A a.3.1 Cytochrome c
View Download 0.233 N/A N/A a.74.1 Cyclin-like
View Download 0.232 N/A N/A a.39.1 EF-hand
View Download 0.227 N/A N/A a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.226 N/A N/A a.181.1 Antibiotic binding domain of TipA-like multidrug resistance regulators
View Download 0.225 N/A N/A a.130.1 Chorismate mutase II
View Download 0.221 N/A N/A a.16.1 S15/NS1 RNA-binding domain
View Download 0.220 N/A N/A a.2.10 Epsilon subunit of F1F0-ATP synthase C-terminal domain
View Download 0.217 N/A N/A a.24.9 alpha-catenin/vinculin
View Download 0.216 N/A N/A a.54.1 Domain of early E2A DNA-binding protein, ADDBP
View Download 0.213 N/A N/A a.24.9 alpha-catenin/vinculin
View Download 0.210 N/A N/A a.100.1 6-phosphogluconate dehydrogenase C-terminal domain-like
View Download 0.207 N/A N/A a.24.3 Cytochromes
View Download 0.205 N/A N/A a.26.1 4-helical cytokines
View Download 0.201 N/A N/A d.87.1 FAD/NAD-linked reductases, dimerisation (C-terminal) domain

Predicted Domain #2
Region A:
Residues: [91-366]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SDVAQRQSMK LIYLKKSVES FINFLTLLQD YKLLDPLVGE KLGNFKDRYN PQLSELYAQP  60
   61 KNNKDLSGAQ LKRKEKIELF QRNKEISTKL HCLELELKNN DEDHDHDELL RELYLMRLHH 120
  121 FSLDTINNIE QNLFECEMLS NFLKNSVHEV KSSGTQIRKE SNDDDSTGFT DKLENINKPL 180
  181 IDKKGQVLRN FTLVDKRQQL QQKVRGYGQY GPTMSVEEFL DKEFEEGRVL QGGEEPEQAP 240
  241 DEENMDWQDR ETYKAREWDE FKESHAKGSG NTMNRG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.564 a.61.1 Retroviral matrix proteins
View Download 0.359 a.24.17 Group V grass pollen allergen
View Download 0.310 a.60.6 DNA polymerase beta, N-terminal domain-like
View Download 0.284 a.74.1 Cyclin-like
View Download 0.283 a.60.6 DNA polymerase beta, N-terminal domain-like


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle