YRC Public Data Repository - Protein Structure Prediction

Protein:	FMS1
Organism:	Saccharomyces cerevisiae
Length:	508 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FMS1.

Description	E-value	Query Range	Subject Range
FMS1_YEAST - Polyamine oxidase FMS1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=FMS1 PE=1 SV=1 FMS1 - Polyamine oxidase, converts spermine to spermidine, which is required for the essential hypusination... gi\|190408259 - gi\|190408259\|gb\|EDV11524.1\| FMS1 [Saccharomyces cerevisiae RM11-1a]	9.0E-99	[1..508]	[1..508]
gi\|8918484 - gi\|8918484\|dbj\|BAA97653.1\| acetylspermidine oxidase [Candida boidinii]	8.0E-64	[4..504]	[1..501]
gi\|31981608, gi\|... - gi\|31981608\|ref\|NP_598653.2\| L-amino acid oxidase 1 [Mus musculus], gi\|17160846\|gb\|AAH17599.1\| L-ami...	3.0E-62	[5..503]	[54..508]
CRTI_ESCVU - Phytoene desaturase (lycopene-forming) OS=Escherichia vulneris GN=crtI PE=3 SV=1 CRTI_ERWHE, CRTI... - (P22871) Phytoene dehydrogenase (EC 1.14.99.-) (Phytoene desaturase), (P22871) Phytoene dehydrogenas...	4.0E-62	[9..507]	[2..491]
gi\|13517069 - gi\|13517069\|dbj\|BAB40417.1\| putative monoamine oxidase A [Cavia porcellus]	2.0E-61	[3..507]	[8..463]
gi\|2244987, gi\|1... - pir\|\|F71429 hypothetical protein - Arabidopsis thaliana, gi\|7268380\|emb\|CAB78673.1\| hypothetical pr...	4.0E-61	[8..508]	[617..1088]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	5.0E-61	[1..507]	[1..477]
gi\|9368354 - gi\|9368354\|emb\|CAB98166.1\| putative corticosteroid binding protein [Brassica napus]	8.0E-61	[8..508]	[578..1053]
CBP1_CANAL - Corticosteroid-binding protein OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=CBP1 PE=1 SV=2 gi\|238880304 - gi\|238880304\|gb\|EEQ43942.1\| conserved hypothetical protein [Candida albicans WO-1] CBP1_CANAL - Corticosteroid-binding protein OS=Candida albicans GN=CBP1 PE=1 SV=2	9.0E-61	[1..507]	[1..477]

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Predicted Domain #1

Region A:
Residues: [1-89]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNTVSPAKKK VIIIGAGIAG LKAASTLHQN GIQDCLVLEA RDRVGGRLQT VTGYQGRKYD  60
   61 IGASWHHDTL TNPLFLEEAQ LSLNDGRTR

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [102-295]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EERGRVDHDK ELLLEIVDNE MSKFAELEFH QHLGVSDCSF FQLVMKYLLQ RRQFLTNDQI  60
   61 RYLPQLCRYL ELWHGLDWKL LSAKDTYFGH QGRNAFALNY DSVVQRIAQS FPQNWLKLSC 120
  121 EVKSITREPS KNVTVNCEDG TVYNADYVII TVPQSVLNLS VQPEKNLRGR IEFQPPLKPV 180
  181 IQDAFDKIHF GALG

[Run NCBI BLAST on this sequence.]

Region C:
Residues: [439-508]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NWTRDPYSRG AYSACFPGDD PVDMVVAMSN GQDSRIRFAG EHTIMDGAGC AYGAWESGRR  60
   61 EATRISDLLK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	177.67837
Match:	1b37A_
Description:	Polyamine oxidase
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [90-101]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FVFDDDNFIY ID

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [296-438]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KVIFEFEECC WSNESSKIVT LANSTNEFVE IVRNAENLDE LDSMLEREDS QKHTSVTCWS  60
   61 QPLFFVNLSK STGVASFMML MQAPLTNHIE SIREDKERLF SFFQPVLNKI MKCLDSEDVI 120
  121 DGMRPIENIA NANKPVLRNI IVS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	177.67837
Match:	1b37A_
Description:	Polyamine oxidase
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits