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View Structure Prediction Details

Protein: PRE8
Organism: Saccharomyces cerevisiae
Length: 250 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PRE8.

Description E-value Query
Range		 Subject
Range
PSA2_NEUCR - Probable proteasome subunit alpha type-2 OS=Neurospora crassa GN=B14D6.510 PE=3 SV=1
PSA2_NEUCR - Probable proteasome subunit alpha type-2 OS=Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS ...
 3.0E-82 [1..250] [1..249]
PSA_PYRAB - Proteasome subunit alpha OS=Pyrococcus abyssi (strain GE5 / Orsay) GN=psmA PE=3 SV=1
PSMA_PYRAB - Proteasome subunit alpha OS=Pyrococcus abyssi GN=psmA PE=3 SV=1
 2.0E-79 [3..247] [8..234]
PSA_PYRHO - Proteasome subunit alpha OS=Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC ...
PSMA_PYRHO - Proteasome subunit alpha OS=Pyrococcus horikoshii GN=psmA PE=3 SV=1
 7.0E-79 [3..248] [8..235]
gi|207342584 - gi|207342584|gb|EDZ70309.1| YML092Cp-like protein [Saccharomyces cerevisiae AWRI1631]
gi|190408154 - gi|190408154|gb|EDV11419.1| proteasome component Y7 [Saccharomyces cerevisiae RM11-1a]
PRE8 - Alpha 2 subunit of the 20S proteasome
PSA2_YEAST - Proteasome subunit alpha type-2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PRE8 PE=...
 2.0E-78 [1..250] [1..250]
PSA_PYRFU - Proteasome subunit alpha OS=Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1) GN=p...
PSMA_PYRFU - Proteasome subunit alpha OS=Pyrococcus furiosus GN=psmA PE=3 SV=1
 5.0E-78 [3..247] [8..234]
PSA7L_MOUSE - Proteasome subunit alpha type-7-like OS=Mus musculus GN=Psma8 PE=1 SV=1
 4.0E-77 [1..241] [1..240]
PSA7_CARAU - Proteasome subunit alpha type-7 OS=Carassius auratus GN=psma7 PE=2 SV=1
 2.0E-76 [1..233] [1..232]
PSA_THEK1 - Proteasome subunit alpha OS=Thermococcus sp. (strain JCM 11816 / KS-1) GN=psmA PE=3 SV=1
PSA_THEK1, PSMA_... - Proteasome subunit alpha OS=Thermococcus sp. (strain KS-1) GN=psmA PE=3 SV=1, Proteasome subunit alp...
gi|11265988 - pir||T43887 proteasome alpha chain [imported] - Thermococcus sp
 5.0E-76 [3..245] [8..232]
gi|7435881 - pir||D69191 proteasome, alpha subunit - Methanobacterium thermoautotrophicum (strain Delta H)
PSA_METTH - Proteasome subunit alpha OS=Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / J...
 1.0E-75 [2..250] [6..238]

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Predicted Domain #1
Region A:
Residues: [1-250] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTDRYSFSLT TFSPSGKLGQ IDYALTAVKQ GVTSLGIKAT NGVVIATEKK SSSPLAMSET  60
   61 LSKVSLLTPD IGAVYSGMGP DYRVLVDKSR KVAHTSYKRI YGEYPPTKLL VSEVAKIMQE 120
  121 ATQSGGVRPF GVSLLIAGHD EFNGFSLYQV DPSGSYFPWK ATAIGKGSVA AKTFLEKRWN 180
  181 DELELEDAIH IALLTLKESV EGEFNGDTIE LAIIGDENPD LLGYTGIPTD KGPRFRKLTS 240
  241 QEINDRLEAL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1469.30103
Match: 1fntP_
Description: CRYSTAL STRUCTURE OF THE 20S PROTEASOME FROM YEAST IN COMPLEX WITH THE PROTEASOME ACTIVATOR PA26 FROM TRYPANOSOME BRUCEI AT 3.2 ANGSTROMS RESOLUTION
Matching Structure (courtesy of the PDB):
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle