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View Structure Prediction Details

Protein: MFT1
Organism: Saccharomyces cerevisiae
Length: 392 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MFT1.

Description E-value Query
Range
Subject
Range
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
4.0E-46 [4..392] [70..470]
MFT1_YEAST - THO complex subunit MFT1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MFT1 PE=1 SV=1
MFT1 - Subunit of the THO complex, which is a nuclear complex comprised of Hpr1p, Mft1p, Rlr1p, and Thp2p, ...
gi|190408181 - gi|190408181|gb|EDV11446.1| mitochondrial targeting protein [Saccharomyces cerevisiae RM11-1a]
gi|207342546 - gi|207342546|gb|EDZ70282.1| YML062Cp-like protein [Saccharomyces cerevisiae AWRI1631]
1.0E-44 [1..392] [1..392]
SPCC737.08 - midasin
MDN1_SCHPO - Midasin OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=mdn1 PE=1 SV=1
3.0E-43 [40..392] [3921..4228]
CG13185-PB - This gene is referred to in FlyBase by the symbol Dmel\CG13185 (CG13185, FBgn0033661). It is a prote...
4.0E-43 [29..382] [4376..4781]
MYO7_ARATH - Myosin-7 OS=Arabidopsis thaliana GN=XI-A PE=3 SV=1
1.0E-37 [40..369] [880..1217]
gi|15212037 - gi|15212037|emb|CAC51118.1| putative bifunctional autolysin [Staphylococcus xylosus]
8.0E-34 [4..388] [70..467]
NCKX1_RAT - Sodium/potassium/calcium exchanger 1 OS=Rattus norvegicus GN=Slc24a1 PE=2 SV=1
2.0E-32 [74..368] [651..930]

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Predicted Domain #1
Region A:
Residues: [1-72]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPLSQKQIDQ VRTKVHYSEV DTPFNKYLDI LGKVTKLTGS IINGTLSNDD SKIEKLTEQN  60
   61 ISQLKESAHL RF

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.540 0.118 DNA recombination a.60.2 RuvA domain 2-like
View Download 0.537 0.023 RNA elongation from RNA polymerase II promoter a.144.1 PABC (PABP) domain
View Download 0.619 0.021 RNA elongation from RNA polymerase II promoter a.7.7 BAG domain
View Download 0.680 0.006 RNA elongation from RNA polymerase II promoter a.13.1 alpha-2-Macroglobulin receptor associated protein (RAP) domain 1
View Download 0.518 0.004 RNA elongation from RNA polymerase II promoter a.144.2 Ribosomal protein L20
View Download 0.513 N/A N/A a.48.3 Conserved domain common to transcription factors TFIIS, elongin A, CRSP70
View Download 0.501 N/A N/A a.2.8 Eukaryotic DNA topoisomerase I, dispensable insert domain
View Download 0.480 N/A N/A a.60.6 DNA polymerase beta, N-terminal domain-like
View Download 0.478 N/A N/A a.60.11 Hypothetical protein YjbJ
View Download 0.471 N/A N/A a.16.1 S15/NS1 RNA-binding domain
View Download 0.430 N/A N/A f.17.1 F1F0 ATP synthase subunit C
View Download 0.423 N/A N/A a.56.1 CO dehydrogenase ISP C-domain like
View Download 0.408 N/A N/A d.94.1 HPr-like
View Download 0.405 N/A N/A a.13.1 alpha-2-Macroglobulin receptor associated protein (RAP) domain 1
View Download 0.404 N/A N/A a.3.1 Cytochrome c
View Download 0.381 N/A N/A a.144.1 PABC (PABP) domain
View Download 0.372 N/A N/A a.126.1 Serum albumin-like
View Download 0.368 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.367 N/A N/A a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.365 N/A N/A a.60.2 RuvA domain 2-like
View Download 0.359 N/A N/A a.144.1 PABC (PABP) domain
View Download 0.329 N/A N/A a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.327 N/A N/A a.24.3 Cytochromes
View Download 0.321 N/A N/A a.144.2 Ribosomal protein L20
View Download 0.317 N/A N/A a.23.4 Mitochondrial import receptor subunit Tom20
View Download 0.313 N/A N/A a.60.6 DNA polymerase beta, N-terminal domain-like
View Download 0.311 N/A N/A a.118.1 ARM repeat
View Download 0.300 N/A N/A a.12.1 Kix domain of CBP (creb binding protein)
View Download 0.299 N/A N/A a.4.8 Ribosomal protein S18
View Download 0.298 N/A N/A a.7.6 Ribosomal protein S20
View Download 0.297 N/A N/A a.60.2 RuvA domain 2-like
View Download 0.282 N/A N/A a.126.1 Serum albumin-like
View Download 0.281 N/A N/A a.16.1 S15/NS1 RNA-binding domain
View Download 0.280 N/A N/A a.23.1 HSC20 (HSCB), C-terminal oligomerisation domain
View Download 0.279 N/A N/A a.8.1 Bacterial immunoglobulin/albumin-binding domains
View Download 0.273 N/A N/A a.24.17 Group V grass pollen allergen
View Download 0.264 N/A N/A a.74.1 Cyclin-like
View Download 0.260 N/A N/A d.15.1 Ubiquitin-like
View Download 0.253 N/A N/A d.120.1 Cytochrome b5
View Download 0.253 N/A N/A a.2.3 Chaperone J-domain
View Download 0.251 N/A N/A a.60.1 SAM/Pointed domain
View Download 0.248 N/A N/A c.102.1 Cell-division inhibitor MinC, N-terminal domain
View Download 0.246 N/A N/A a.29.4 RecG, N-terminal domain
View Download 0.244 N/A N/A a.29.4 RecG, N-terminal domain
View Download 0.240 N/A N/A a.156.1 S13-like H2TH domain
View Download 0.231 N/A N/A c.10.2 L domain-like
View Download 0.231 N/A N/A a.5.3 N-terminal domain of phosphatidylinositol transfer protein sec14p
View Download 0.228 N/A N/A a.2.1 GreA transcript cleavage protein, N-terminal domain
View Download 0.227 N/A N/A a.144.1 PABC (PABP) domain
View Download 0.226 N/A N/A a.2.9 C-terminal UvrC-binding domain of UvrB
View Download 0.222 N/A N/A a.35.1 lambda repressor-like DNA-binding domains
View Download 0.222 N/A N/A a.2.7 tRNA-binding arm
View Download 0.220 N/A N/A a.47.2 t-snare proteins
View Download 0.218 N/A N/A a.81.1 N-terminal domain of DnaB helicase
View Download 0.215 N/A N/A a.5.2 UBA-like
View Download 0.213 N/A N/A a.13.1 alpha-2-Macroglobulin receptor associated protein (RAP) domain 1
View Download 0.212 N/A N/A a.2.11 Fe,Mn superoxide dismutase (SOD), N-terminal domain
View Download 0.212 N/A N/A a.39.1 EF-hand
View Download 0.210 N/A N/A a.144.1 PABC (PABP) domain
View Download 0.206 N/A N/A a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.206 N/A N/A a.7.2 Enzyme IIa from lactose specific PTS, IIa-lac
View Download 0.206 N/A N/A a.65.1 Annexin
View Download 0.205 N/A N/A a.2.7 tRNA-binding arm
View Download 0.205 N/A N/A a.60.11 Hypothetical protein YjbJ
View Download 0.203 N/A N/A a.144.1 PABC (PABP) domain
View Download 0.203 N/A N/A f.14.1 Voltage-gated potassium channels
View Download 0.201 N/A N/A a.48.3 Conserved domain common to transcription factors TFIIS, elongin A, CRSP70

Predicted Domain #2
Region A:
Residues: [73-202]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LDLQSSIDTK KVADENWETC QQETLAKLEN LKDKLPDIKS IHSKLLLRIG KLQGLYDSVQ  60
   61 VINREVEGLS EGRTSLVVTR AEWEKELGTD LVKFLIEKNY LKLVDPGLKK DSSEERYRIY 120
  121 DDFSKGPKEL 

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 7.5
Match: 1l8mA
Description: No description for 1l8mA was found.

Predicted Domain #3
Region A:
Residues: [203-281]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ESINASMKSD IENVRQEVSS YKEKWLRDAE IFGKITSIFK EELLKRDGLL NEAEGDNIDE  60
   61 DYESDEDEER KERFKRQRS

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 7.5
Match: 1l8mA
Description: No description for 1l8mA was found.

Predicted Domain #4
Region A:
Residues: [282-392]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVEVNTIENV DEKEESDHEY DDQEDEENEE EDDMEVDVED IKEDNEVDGE SSQQEDNSRQ  60
   61 GNNEETDKET GVIEEPDAVN DAEEADSDHS SRKLGGTTSD FSASSSVEEV K

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 7.5
Match: 1l8mA
Description: No description for 1l8mA was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle