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View Structure Prediction Details

Protein: CMP2
Organism: Saccharomyces cerevisiae
Length: 604 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CMP2.

Description E-value Query
Range
Subject
Range
PP2B2_YEAST - Serine/threonine-protein phosphatase 2B catalytic subunit A2 OS=Saccharomyces cerevisiae (strain ATC...
CMP2 - Calcineurin A; one isoform (the other is CNA1) of the catalytic subunit of calcineurin, a Ca++/calmo...
0.0 [1..604] [1..604]
gi|14495188 - gi|14495188|dbj|BAB60952.1| calcineurin A [Aspergillus oryzae]
0.0 [59..603] [1..503]
gi|85101677 - gi|85101677|ref|XP_961193.1| phosphoprotein phosphatase 3-alpha catalytic chain [MIPS] [Neurospora c...
gi|11595623, gi|... - gi|32404984|ref|XP_323105.1| phosphoprotein phosphatase 3-alpha catalytic chain [MIPS] [Neurospora c...
0.0 [59..604] [1..507]
PP2B_EMENI, P2B_... - Serine/threonine-protein phosphatase 2B catalytic subunit (EC 3.1.3.16) (Calmodulin-dependent calcin...
0.0 [59..603] [1..506]
gi|447739 - gi|447739|prf||1915304A nylB upstream ORF
0.0 [59..603] [1..506]
gi|17978561 - gi|17978561|gb|AAL47191.1| calcineurin [Exophiala dermatitidis]
0.0 [50..603] [16..526]
ppb1 - calcineurin catalytic subunit Ppb1
PP2B_SCHPO - Serine/threonine-protein phosphatase 2B catalytic subunit OS=Schizosaccharomyces pombe (strain 972 /...
0.0 [28..595] [1..535]

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Predicted Domain #1
Region A:
Residues: [1-604]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSDAIRNTE QINAAIKIIE NKTERPQSST TPIDSKASTV AAANSTATET SRDLTQYTLD  60
   61 DGRVVSTNRR IMNKVPAITS HVPTDEELFQ PNGIPRHEFL RDHFKREGKL SAAQAARIVT 120
  121 LATELFSKEP NLISVPAPIT VCGDIHGQYF DLLKLFEVGG DPATTSYLFL GDYVDRGSFS 180
  181 FECLIYLYSL KLNFNDHFWL LRGNHECKHL TSYFTFKNEM LHKYNLDIYE KCCESFNNLP 240
  241 LAALMNGQYL CVHGGISPEL NSLQDINNLN RFREIPSHGL MCDLLWADPI EEYDEVLDKD 300
  301 LTEEDIVNSK TMVPHHGKMA PSRDMFVPNS VRGCSYAFTY RAACHFLQET GLLSIIRAHE 360
  361 AQDAGYRMYK NTKTLGFPSL LTLFSAPNYL DTYNNKAAIL KYENNVMNIR QFNMTPHPYW 420
  421 LPDFMDVFTW SLPFVGEKVT EMLVAILNIC TEDELENDTP VIEELVGTDK KLPQAGKSEA 480
  481 TPQPATSASP KHASILDDEH RRKALRNKIL AVAKVSRMYS VLREETNKVQ FLKDHNSGVL 540
  541 PRGALSNGVK GLDEALSTFE RARKHDLINE KLPPSLDELK NENKKYYEKV WQKVHEHDAK 600
  601 NDSK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1724.0
Match: 1auiA_
Description: Protein phosphatase-2B (PP-2B, calcineurin A subunit)
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle