YRC Public Data Repository - Protein Structure Prediction

Protein:	VPS71
Organism:	Saccharomyces cerevisiae
Length:	280 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for VPS71.

Description	E-value	Query Range	Subject Range
gi\|190408202 - gi\|190408202\|gb\|EDV11467.1\| vacuolar protein sorting protein 71 [Saccharomyces cerevisiae RM11-1a] gi\|207342507 - gi\|207342507\|gb\|EDZ70255.1\| YML041Cp-like protein [Saccharomyces cerevisiae AWRI1631] VPS71_YEAST - Vacuolar protein sorting-associated protein 71 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S28... VPS71 - Nucleosome-binding component of the SWR1 complex, which exchanges histone variant H2AZ (Htz1p) for c... gi\|151946123 - gi\|151946123\|gb\|EDN64354.1\| vacuolar sorting protein [Saccharomyces cerevisiae YJM789]	0.0	[1..280]	[1..280]
gi\|49527538, gi\|... - gi\|50291589\|ref\|XP_448227.1\| unnamed protein product [Candida glabrata], gi\|49527538\|emb\|CAG61178.1\|... gi\|49527538, gi\|... - gi\|5901753\|gb\|AAD55397.1\| hypothetical protein [Candida glabrata], gi\|49527538\|emb\|CAG61178.1\| unnam...	1.0E-95	[5..280]	[7..271]
SPBC29A3.05 - chromatin remodeling complex subunit VPS71_SCHPO - SWR1 complex subunit vps71 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=vps71 PE=1 SV=2	3.0E-23	[196..277]	[62..134]
gi\|73957813 - gi\|73957813\|ref\|XP_536855.2\| PREDICTED: similar to Zinc finger HIT domain containing protein 1 (Cycl... ZNHI1_BOVIN - Zinc finger HIT domain-containing protein 1 OS=Bos taurus GN=ZNHIT1 PE=2 SV=1 ENSCJAT00000031181 - null ZNHIT1 - zinc finger, HIT type 1 CCDS5716.1_1 - null gi\|114615130 - gi\|114615130\|ref\|XP_527843.2\| PREDICTED: zinc finger, HIT domain containing 1 [Pan troglodytes] gi\|109066182 - gi\|109066182\|ref\|XP_001107951.1\| PREDICTED: zinc finger, HIT type 1 isoform 2 [Macaca mulatta] gi\|123982920, gi... - gi\|123997601\|gb\|ABM86402.1\| zinc finger, HIT type 1 [synthetic construct], gi\|123982920\|gb\|ABM83201.... gi\|149755986 - gi\|149755986\|ref\|XP_001504511.1\| PREDICTED: similar to Zinc finger HIT domain-containing protein 1 (...	3.0E-12	[186..277]	[66..149]
gi\|12848798, gi\|... - gi\|58037197\|ref\|NP_081594.1\| zinc finger, HIT domain containing 1 [Mus musculus], gi\|26348771\|dbj\|BA... tr\|D3ZNG9\|D3ZNG9_RAT - Uncharacterized protein OS=Rattus norvegicus GN=Znhit1	4.0E-12	[186..277]	[65..148]
SWC6_ARATH - SWR1 complex subunit 6 OS=Arabidopsis thaliana GN=SWC6 PE=1 SV=1	1.0E-11	[186..277]	[73..166]
gi\|12039342 - gi\|12039342\|gb\|AAG46129.1\|AC082644_11 hypothetical protein [Oryza sativa]	8.0E-11	[186..277]	[129..221]

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Predicted Domain #1

Region A:
Residues: [1-182]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKALVEEIDK KTYNPDIYFT SLDPQARRYT SKKINKQGTI STSRPVKRIN YSLADLEARL  60
   61 YTSRSEGDGN SISRQDDRNS KNSHSFEERY TQQEILQSDR RFMELNTENF SDLPNVPTLL 120
  121 SDLTGVPRDR IESTTKPISQ TSDGLSALMG GSSFVKEHSK YGHGWVLKPE TLREIQLSYK 180
  181 ST

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [183-280]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KLPKPKRKNT NRIVALKKVL SSKRNLHSFL DSALLNLMDK NVIYHNVYNK RYFKVLPLIT  60
   61 TCSICGGYDS ISSCVNCGNK ICSVSCFKLH NETRCRNR

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.396	0.698	Swr1 complex	b.1.1	Immunoglobulin
View	Download	0.396	0.641	Swr1 complex	b.1.1	Immunoglobulin
View	Download	0.390	0.148	Swr1 complex	a.39.1	EF-hand
View	Download	0.390	0.136	Swr1 complex	a.39.1	EF-hand
View	Download	0.477	0.025	Swr1 complex	a.100.1	6-phosphogluconate dehydrogenase C-terminal domain-like
View	Download	0.428	0.024	Swr1 complex	a.77.1	DEATH domain
View	Download	0.477	0.023	Swr1 complex	a.100.1	6-phosphogluconate dehydrogenase C-terminal domain-like
View	Download	0.428	0.022	Swr1 complex	a.77.1	DEATH domain
View	Download	0.551	0.006	Swr1 complex	a.80.1	DNA polymerase III clamp loader subunits, C-terminal domain
View	Download	0.551	0.006	Swr1 complex	a.80.1	DNA polymerase III clamp loader subunits, C-terminal domain
View	Download	0.388	N/A	N/A	a.74.1	Cyclin-like
View	Download	0.364	N/A	N/A	a.69.3	1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain
View	Download	0.359	N/A	N/A	a.24.7	FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)
View	Download	0.355	N/A	N/A	a.80.1	DNA polymerase III clamp loader subunits, C-terminal domain
View	Download	0.352	N/A	N/A	a.70.1	N-terminal domain of the delta subunit of the F1F0-ATP synthase
View	Download	0.336	N/A	N/A	d.53.1	Ribosomal protein S3 C-terminal domain
View	Download	0.334	N/A	N/A	c.78.2	Aspartate/glutamate racemase
View	Download	0.329	N/A	N/A	a.46.1	Methionine synthase domain
View	Download	0.326	N/A	N/A	a.39.2	Insect pheromon/odorant-binding proteins
View	Download	0.310	N/A	N/A	a.118.1	ARM repeat
View	Download	0.303	N/A	N/A	d.150.1	4'-phosphopantetheinyl transferase
View	Download	0.302	N/A	N/A	a.77.1	DEATH domain
View	Download	0.283	N/A	N/A	a.27.1	Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View	Download	0.281	N/A	N/A	a.118.1	ARM repeat
View	Download	0.280	N/A	N/A	a.49.1	C-terminal domain of B transposition protein
View	Download	0.271	N/A	N/A	d.17.1	Cystatin/monellin
View	Download	0.256	N/A	N/A	a.60.8	HRDC-like
View	Download	0.247	N/A	N/A	d.58.7	RNA-binding domain, RBD
View	Download	0.240	N/A	N/A	a.1.1	Globin-like
View	Download	0.229	N/A	N/A	a.88.1	LigA subunit of an aromatic-ring-opening dioxygenase LigAB
View	Download	0.226	N/A	N/A	d.15.6	Superantigen toxins, C-terminal domain
View	Download	0.223	N/A	N/A	a.3.1	Cytochrome c
View	Download	0.217	N/A	N/A	d.58.1	4Fe-4S ferredoxins

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits