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View Structure Prediction Details

Protein: USA1
Organism: Saccharomyces cerevisiae
Length: 838 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for USA1.

Description E-value Query
Range
Subject
Range
USA1_YEAST - U1 SNP1-associating protein 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=USA1 PE=1 ...
USA1 - Protein involved in ER-associated protein degradation (ERAD); component of the Hrd1p complex; intera...
gi|190408211 - gi|190408211|gb|EDV11476.1| U1 SNP1-associating protein 1 [Saccharomyces cerevisiae RM11-1a]
gi|207342497 - gi|207342497|gb|EDZ70248.1| YML029Wp-like protein [Saccharomyces cerevisiae AWRI1631]
0.0 [1..838] [1..838]

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Predicted Domain #1
Region A:
Residues: [1-838]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSEYLAQTPC KFTIWSSEID LIRTNLLVNA HPLSTVGRLL QYIHYQIYKQ LRAIYQPEEQ  60
   61 CTNSEIPHTP LNSINTYFLS YEGRELSATC LLKDITSSSH PDSNHFIRLQ LEKRTSPSGS 120
  121 AFDLEYDMEG EFNSMNIQFE INTLSSQRIF NSMEPNLPIG TTLARLEKLA LERIKDFEKS 180
  181 AGNLCGIKED HSVSDLQGFI IKGKQTPMFL NYGSDSDYYK DLNLVDLIGI DFAPAHNSFF 240
  241 TFLFKMNHEQ NSHIANDEER FVLEFISDAT LSITQMNVKP DTTVKQVKDF ICSVYTHSLN 300
  301 LRRNDIKLIY KGQLLHENNF AGNSSKISEY IKEPHEVKVH VQINQEYTES GPGFWNEVFN 360
  361 NPNIFQFMPP DTRSQSPVSF APTQGRSPAA IRGEERGIPY VTESGNDIVP TDELYRKCII 420
  421 NGDEVVFIPV SELNPQSSYL SVIKGDYGEI KIPISSNDYR INGDNILLSP SAIEQLESAL 480
  481 NFKIERPRDS TLLHPSGEHV RAADNTSSAN DNNTVENDES AWNRRVVRPL RNSFPLLLVL 540
  541 IRTFYLIGYN SLVPFFIILE FGSFLPWKYI ILLSLLFIFR TVWNTQEVWN LWRDYLHLNE 600
  601 IDEVKFSQIK EFINSNSLTL NFYKKCKDTQ SAIDLLMIPN LHEQRLSVYS KYDIEYDTNT 660
  661 PDVGQLNLLF IKVLSGEIPK DALDELFKEF FELYETTRNM NTLYPQDSLN ELLLMIWKES 720
  721 QKKDINTLPK YRRWFQTLCS QIAEHNVLDV VLRYIIPDPV NDRVITAVIK NFVLFWVTLL 780
  781 PYVKEKLDDI VAQRARDREQ PAPSAQQQEN EDEALIIPDE EEPTATGAQP HLYIPDED

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [215-369]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DSDYYKDLNL VDLIGIDFAP AHNSFFTFLF KMNHEQNSHI ANDEERFVLE FISDATLSIT  60
   61 QMNVKPDTTV KQVKDFICSV YTHSLNLRRN DIKLIYKGQL LHENNFAGNS SKISEYIKEP 120
  121 HEVKVHVQIN QEYTESGPGF WNEVFNNPNI FQFMP

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.06
Match: 1se9A
Description: Structure of At3g01050, a ubiquitin-fold protein from Arabidopsis thaliana
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [370-518]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PDTRSQSPVS FAPTQGRSPA AIRGEERGIP YVTESGNDIV PTDELYRKCI INGDEVVFIP  60
   61 VSELNPQSSY LSVIKGDYGE IKIPISSNDY RINGDNILLS PSAIEQLESA LNFKIERPRD 120
  121 STLLHPSGEH VRAADNTSSA NDNNTVEND

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.496 b.29.1 Concanavalin A-like lectins/glucanases
View Download 0.374 d.24.1 Pili subunits
View Download 0.358 a.1.1 Globin-like
View Download 0.314 a.4.3 ARID-like
View Download 0.289 a.1.1 Globin-like

Predicted Domain #4
Region A:
Residues: [519-721]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ESAWNRRVVR PLRNSFPLLL VLIRTFYLIG YNSLVPFFII LEFGSFLPWK YIILLSLLFI  60
   61 FRTVWNTQEV WNLWRDYLHL NEIDEVKFSQ IKEFINSNSL TLNFYKKCKD TQSAIDLLMI 120
  121 PNLHEQRLSV YSKYDIEYDT NTPDVGQLNL LFIKVLSGEI PKDALDELFK EFFELYETTR 180
  181 NMNTLYPQDS LNELLLMIWK ESQ

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [722-838]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KKDINTLPKY RRWFQTLCSQ IAEHNVLDVV LRYIIPDPVN DRVITAVIKN FVLFWVTLLP  60
   61 YVKEKLDDIV AQRARDREQP APSAQQQENE DEALIIPDEE EPTATGAQPH LYIPDED

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.407 d.58.26 GHMP Kinase, C-terminal domain
View Download 0.315 a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.311 a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.293 a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.254 a.100.1 6-phosphogluconate dehydrogenase C-terminal domain-like


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle