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View Structure Prediction Details

Protein: YLR460C
Organism: Saccharomyces cerevisiae
Length: 376 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YLR460C.

Description E-value Query
Range		 Subject
Range
ADHX_SPAAU - Alcohol dehydrogenase class-3 OS=Sparus aurata PE=2 SV=1
 0.0 [2..371] [1..374]
gi|2570190 - gi|2570190|dbj|BAA22979.1| alcohol dehydrogenase [Arabidopsis thaliana]
 0.0 [2..371] [1..375]
ADH1_PEA - Alcohol dehydrogenase 1 OS=Pisum sativum PE=1 SV=1
 0.0 [1..371] [1..376]
gi|6684357 - gi|6684357|gb|AAF23539.1|AF110441_1 alcohol dehydrogenase [Halimolobos perplexa var. lemhiensis]
 0.0 [2..371] [1..375]
gi|2570182, gi|2... - gi|2570182|dbj|BAA22976.1| alcohol dehydrogenase [Arabidopsis halleri subsp. gemmifera], gi|2570176|...
 0.0 [2..371] [1..375]

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Predicted Domain #1
Region A:
Residues: [1-159] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQVAIPETMK AVVIEDGKAV VKEGIPIPEL EEGFVLIKTL AVAGNPTDWA HIDYKIGPQG  60
   61 SILGCDAAGQ IVKLGPAVNP KDFSIGDYIY GFIHGSSVRF PSNGAFAEYS AISTVVAYKS 120
  121 PNELKFLGED VLPAGPVRSL EGVATIPVSL TTAGLVLTY

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [304-376] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HEVPFGNITL PADSEARKAA IKFIKFINPK INDGQIRHIP VRVYKNGLCD VPHILKDIKY  60
   61 GKNSGEKLVA VLN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 113.0
Match: 1tehA_
Description: Alcohol dehydrogenase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
oxidoreductase activity 4.14217990101505 bayes_pls_golite062009
oxidoreductase activity, acting on CH-OH group of donors 2.13774251017711 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1.96417104841008 bayes_pls_golite062009
catalytic activity 1.79741889688267 bayes_pls_golite062009
alcohol dehydrogenase (NAD) activity 1.68027744358887 bayes_pls_golite062009
chaperone binding 0.983752799796442 bayes_pls_golite062009
alcohol dehydrogenase activity, zinc-dependent 0.839863523675468 bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity 0.527946013169731 bayes_pls_golite062009
binding 0.429102711245135 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [160-303] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NLGLDLKWEP STPQRKGPIL LWGGATAVGQ SLIQLANKLN GFTKIIVVAS RKHEKLLKEY  60
   61 GADELFDYHD IDVVEQIKHK YNNISYLVDC VANQDTLQQV YKCAADKQDA TIVELKNLTE 120
  121 ENVKKENRRQ NVTIDIIRLY SIGG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 113.0
Match: 1tehA_
Description: Alcohol dehydrogenase
Matching Structure (courtesy of the PDB):
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle