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View Structure Prediction Details

Protein: BUD6
Organism: Saccharomyces cerevisiae
Length: 788 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for BUD6.

Description E-value Query
Range		 Subject
Range
MYH4_PIG - Myosin-4 OS=Sus scrofa GN=MYH4 PE=2 SV=1
 3.0E-96 [14..780] [1095..1855]
gi|8250661 - gi|8250661|gb|AAB29713.2| myosin heavy chain [Rattus sp.]
 5.0E-95 [14..780] [50..810]
MYH1 - myosin, heavy chain 1, skeletal muscle, adult
 7.0E-95 [14..780] [1097..1857]
MYH4_RABIT - Myosin-4 OS=Oryctolagus cuniculus GN=MYH4 PE=1 SV=1
 8.0E-95 [14..780] [1096..1856]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
 9.0E-94 [14..780] [94..854]
gi|6683485 - gi|6683485|dbj|BAA89233.1| skeletal myosin heavy chain [Gallus gallus]
 9.0E-94 [14..780] [1097..1857]

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Predicted Domain #1
Region A:
Residues: [1-79] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKMAVDDPTY GTPKIKRTAS SSSSIETTVT KLLMSTKHLL QVLTQWSKGT TSGRLVSDAY  60
   61 VQLGNDFKVV SKFFMHAKV

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score		 SCOP
Match		 SCOP Description
View Download 0.639 a.4.1 Homeodomain-like
View Download 0.639 a.4.1 Homeodomain-like
View Download 0.798 a.2.11 Fe,Mn superoxide dismutase (SOD), N-terminal domain
View Download 0.798 a.2.11 Fe,Mn superoxide dismutase (SOD), N-terminal domain
View Download 0.548 a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.576 a.30.1 ROP protein
View Download 0.576 a.30.1 ROP protein
View Download 0.579 a.2.8 Eukaryotic DNA topoisomerase I, dispensable insert domain
View Download 0.579 a.2.8 Eukaryotic DNA topoisomerase I, dispensable insert domain
View Download 0.578 a.2.11 Fe,Mn superoxide dismutase (SOD), N-terminal domain
View Download 0.545 a.23.1 HSC20 (HSCB), C-terminal oligomerisation domain
View Download 0.537 a.7.8 GAT domain
View Download 0.537 a.74.1 Cyclin-like
View Download 0.533 a.2.7 tRNA-binding arm
View Download 0.497 a.2.2 Ribosomal protein L29 (L29p)
View Download 0.494 a.74.1 Cyclin-like
View Download 0.492 a.8.3 Families 57/38 glycoside transferase middle domain
View Download 0.482 a.29.3 Acyl-CoA dehydrogenase C-terminal domain-like
View Download 0.477 a.13.1 alpha-2-Macroglobulin receptor associated protein (RAP) domain 1
View Download 0.472 a.30.2 Homodimeric domain of signal transducing histidine kinase
View Download 0.429 a.36.1 Signal peptide-binding domain
View Download 0.413 a.165.1 Myosin phosphatase inhibitor 17kDa protein, CPI-17
View Download 0.393 a.2.3 Chaperone J-domain
View Download 0.391 a.47.2 t-snare proteins
View Download 0.389 a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.378 a.7.1 Spectrin repeat
View Download 0.367 a.4.5 "Winged helix" DNA-binding domain
View Download 0.365 a.74.1 Cyclin-like
View Download 0.354 f.15.1 Small-conductance potassium channel
View Download 0.352 a.2.11 Fe,Mn superoxide dismutase (SOD), N-terminal domain
View Download 0.349 a.36.1 Signal peptide-binding domain
View Download 0.347 a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.337 a.30.2 Homodimeric domain of signal transducing histidine kinase
View Download 0.329 a.7.5 Tubulin chaperone cofactor A
View Download 0.323 a.25.1 Ferritin-like
View Download 0.321 a.46.1 Methionine synthase domain
View Download 0.314 a.2.6 Effector domain of the protein kinase pkn/prk1
View Download 0.311 a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.309 d.52.3 Prokaryotic type KH domain (KH-domain type II)
View Download 0.304 a.7.1 Spectrin repeat
View Download 0.301 a.24.3 Cytochromes
View Download 0.300 a.47.2 t-snare proteins
View Download 0.287 a.2.3 Chaperone J-domain
View Download 0.286 d.203.1 DsrC, the gamma subunit of dissimilatory sulfite reductase
View Download 0.282 a.7.7 BAG domain
View Download 0.280 a.46.2 Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain
View Download 0.278 a.2.7 tRNA-binding arm
View Download 0.272 a.29.4 RecG, N-terminal domain
View Download 0.270 d.120.1 Cytochrome b5
View Download 0.270 a.60.5 Barrier-to-autointegration factor, BAF
View Download 0.254 f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.240 d.42.1 POZ domain
View Download 0.239 a.4.13 Sigma3 and sigma4 domains of RNA polymerase sigma factors
View Download 0.234 a.22.1 Histone-fold
View Download 0.234 a.60.9 lambda integrase-like, N-terminal domain
View Download 0.232 a.56.1 CO dehydrogenase ISP C-domain like
View Download 0.232 a.4.13 Sigma3 and sigma4 domains of RNA polymerase sigma factors
View Download 0.230 a.7.3 Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain
View Download 0.220 a.26.1 4-helical cytokines
View Download 0.216 a.24.3 Cytochromes
View Download 0.215 d.58.44 Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
View Download 0.213 a.112.1 Description not found.
View Download 0.210 a.118.11 Cytochrome c oxidase subunit E
View Download 0.204 a.7.2 Enzyme IIa from lactose specific PTS, IIa-lac
View Download 0.203 a.112.1 Description not found.

Predicted Domain #2
Region A:
Residues: [80-279] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DMSDVGDVPM ALRRVLEVTL REPPSDETLN KHLPKIREII VTLLDKLKVK QAILKNMQQE  60
   61 HRISVKSHHQ QNPSFTSNLS LGSEGTREGT PLSSRKSSIV RDQRQSDSVE NSYGEKVNST 120
  121 STGTPSAQSA EATLTKPRTN IKQNLKSNNA PNASDDDDAL SQLKKGTNLQ RRASKRYSAY 180
  181 HMAKLTNQST TEAAAAAGLM

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 2.69897
Match: 1jchA_
Description: Ribonuclease domain of colicin E3; Colicin E3 translocation domain; Colicin E3 receptor domain
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [280-618] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TTPSPSMLHL EETVRKSKLY GNNNNDDDRN INSAENKGKS IDDVSKASPL AKTPLPIENV  60
   61 RASPRRLSSV VTTSPDKAMN GTCPVFLRIG DKTKKCHVQL PTTKNALRLL FIERFAYSPG 120
  121 ANSFPDIYIM DPQYGVFYEL EELNLLDIKE GFVIELKLEE NPNNTIKEFI DTVKMEISNS 180
  181 QNDIIRHLKE MSFGSAISGK QTEVLPQPGL EANKHDLVGQ NKKDDDKTIK DIQYELGKIK 240
  241 QVHNINRSNI NETIFNILRK VDNFKSLSFS AKNSSNRMYM EKSQTELGDL SDTLLSKVDD 300
  301 LQDVIEIMRK DVAERRSQPA KKKLETVSKD LENAQADVL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 14.69897
Match: 1i84S_
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [619-788] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KLQEFIDTEK PHWKKTWEAE LDKVCEEQQF LTLQEELILD LKEDLGKALE TFDLIKLCCE  60
   61 EQEKNPSRSK SNPILPIMRP GTFNQVREQV MVAVQSLNPD HDSRVEAIDK AEKMWEMERK 120
  121 LKASNEFDDE LENFVGNSNL KKSGGFEEVE RIRKQKDEAN LRAYFGPGFT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 7.522879
Match: 2tmaA_
Description: Tropomyosin
Matching Structure (courtesy of the PDB):
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle